CAS 141136-84-7

H-Phe-Leu-Leu-Arg-Asn-OH

Descrizione:

La sostanza chimica con il nome "H-Phe-Leu-Leu-Arg-Asn-OH" e numero CAS "141136-84-7" è un peptide, specificamente un pentapeptide composto da cinque amminoacidi: fenilalanina (Phe), leucina (Leu), arginina (Arg) e asparagina (Asn). Questo peptide è caratterizzato dalla sua sequenza, che influenza la sua attività biologica e le proprietà. La presenza degli amminoacidi contribuisce alle sue caratteristiche idrofobiche e idrofili, influenzando la solubilità e l'interazione con le membrane biologiche. La "H" terminale indica che è nella sua forma di acido libero, mentre "OH" suggerisce un gruppo acido carbossilico alla fine della catena peptidica. Peptidi come questo possono svolgere ruoli significativi in vari processi biologici, comprese le vie di segnalazione e le risposte immunitarie. Possono anche avere potenziali applicazioni terapeutiche, come nello sviluppo di farmaci o come biomarcatori. Le proprietà specifiche, come stabilità, reattività e attività biologica, possono variare in base alla struttura del peptide e all'ambiente in cui viene studiato.

Formula: C₃₁H₅₁N₉O₇

InChI: InChI=1/C31H51N9O7/c1-17(2)13-22(38-26(42)20(32)15-19-9-6-5-7-10-19)29(45)39-23(14-18(3)4)28(44)37-21(11-8-12-36-31(34)35)27(43)40-24(30(46)47)16-25(33)41/h5-7,9-10,17-18,20-24H,8,11-16,32H2,1-4H3,(H2,33,41)(H,37,44)(H,38,42)(H,39,45)(H,40,43)(H,46,47)(H4,34,35,36)

SMILES: CC(C)CC(C(=NC(CC(C)C)C(=NC(CCCNC(=N)N)C(=NC(CC(=N)O)C(=O)O)O)O)O)N=C(C(Cc1ccccc1)N)O

Sinonimi:

• H 8325
• Fllrn
• Phe-leu-leu-arg-asn
• Phenylalanyl-leucyl-leucyl-arginyl-asparagine
• L-Asparagine, N2-(N2-(N-(N-L-phenylalanyl-L-leucyl)-L-leucyl)-L-arginyl)-

FLLRN

CAS: 141136-84-7

FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.

Formula: C₃₁H₅₁N₉O₇

Colore e forma: Solid

Peso molecolare: 661.79

Ref: TM-T78545

H-Phe-Leu-Leu-Arg-Asn-OH

CAS: 141136-84-7

H-Phe-Leu-Leu-Arg-Asn-OH is a β-amino acid that has been shown to have antioxidant properties. It acts as a competitive inhibitor of the enzyme collagenase and has been shown to inhibit the development of atherosclerotic lesions in mice. The amide form of H-Phe-Leu-Leu-Arg-Asn has also been shown to have site specific activity on ventricular myocardium cells, which may be related to its ability to induce cytosolic calcium release. HPLR also has protease activity that can be inhibited by urea nitrogen and β amino acid. Basophilic leukemia cells produce HPLR at high levels and it is thought that this is due to an increased requirement for the production of collagen in these cells. HPLR has been shown to activate thrombin receptors, which are found on the surface of platelets and endothelial cells. Activated thrombin

Formula: C₃₁H₅₁N₉O₇

Purezza: Min. 95%

Peso molecolare: 661.81 g/mol

Ref: 3D-PAR-3944-PI

TRAP-6 (2-6) trifluoroacetate salt

CAS: 141136-84-7

TRAP-6 (2-6) is a monoclonal antibody that binds to the enzyme collagenase, which is an important factor in tumor invasion and metastasis. The antibody binds to the active site of collagenase, thereby inhibiting its activity. TRAP-6 (2-6) has been shown to reduce the growth of cancer cells by inhibiting the production of β-amino acids and zymogens, which are required for tumor cell proliferation. It also inhibits serine proteases, such as thrombin receptor, which play an important role in tumor invasion and metastasis. TRAP-6 (2-6) also has anti-inflammatory properties and can be used for the treatment of basophilic leukemia.

Formula: C₃₁H₅₁N₉O₇

Purezza: Min. 95%

Peso molecolare: 661.79 g/mol

Ref: 3D-FT110302