CAS 1415558-82-5

2-Keto Crizotinib

CAS: 1415558-82-5

Formula: C₂₁H₂₀Cl₂FN₅O₂

Colore e forma: Off-White Solid

Peso molecolare: 464.32

Ref: 4Z-C-123003

2-Keto Crizotinib

CAS: 1415558-82-5

2-Keto Crizotinib is an active lactam metabolite of crizotinib.

Formula: C₂₁H₂₀Cl₂FN₅O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 464.32

Ref: TM-T19510

2-Keto Crizotinib

Prodotto controllato

CAS: 1415558-82-5

Applications 2-Keto Crizotinib is an impurity of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₂₁H₂₀Cl₂FN₅O₂

Colore e forma: Neat

Peso molecolare: 464.32

Ref: TR-K186500

2-Keto crizotinib

CAS: 1415558-82-5

2-Keto crizotinib is a potent inhibitor of the tyrosine kinase enzyme, which blocks cancer cell growth. It binds to the ATP site of the enzyme and prevents the phosphorylation of tyrosine residues on cellular proteins, thereby inhibiting protein synthesis. 2-Keto crizotinib has been shown to inhibit receptors that are involved in angiogenesis and metastasis. This agent is also a competitive antagonist at the epidermal growth factor receptor (EGFR) and blocks activation by binding to its extracellular domain. 2-Keto crizotinib also has immunosuppressive effects, which may be due to its ability to block antibody production.

Formula: C₂₁H₂₀Cl₂FN₅O₂

Purezza: Min. 95%

Peso molecolare: 464.3 g/mol

Ref: 3D-QGC55882

2-Keto Crizotinib

CAS: 1415558-82-5

Formula: C₂₁H₂₀Cl₂FN₅O₂

Peso molecolare: 464.3

Ref: ST-EA-CP-C101006