CAS 1416799-28-4

AMG-333

CAS: 1416799-28-4

Formula: C₂₀H₁₂F₅N₃O₄

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 453.3190

Ref: IN-DA01LRLX

AMG 333

CAS: 1416799-28-4

AMG 333

Purezza: ≥98%

Peso molecolare: 453.32g/mol

Ref: 54-BUP04902

AMG 333

CAS: 1416799-28-4

AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.

Formula: C₂₀H₁₂F₅N₃O₄

Purezza: 99.95%

Colore e forma: Solid

Peso molecolare: 453.32

Ref: TM-T5479

AMG 333

CAS: 1416799-28-4

AMG 333 is a synthetic, non-selective acetylcholinesterase inhibitor that has been shown to be safe and effective in the treatment of Alzheimer's disease. It selectively blocks the enzyme acetylcholinesterase, which is responsible for breaking down the neurotransmitter acetylcholine. This inhibition allows more acetylcholine to remain active in synapses, resulting in better memory and cognitive function. AMG 333 is highly selective for cholinergic neurons, with minimal activity on other populations such as erythrocytes or skeletal muscle cells. AMG 333 has a pharmacokinetic profile with a half-life of approximately 3 hours and a distribution volume of 0.15 L/kg. Pharmacokinetic studies have found that this drug is rapidly absorbed after oral administration and eliminated primarily by metabolism through the liver and kidneys.
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Formula: C₂₀H₁₂F₅N₃O₄

Purezza: Min. 95%

Peso molecolare: 453.32 g/mol

Ref: 3D-RGC79928