CAS 14197-60-5

Ginsenoside Rg3

Descrizione:

Ginsenoside Rg3 è un composto naturale classificato come una saponina triterpenoide, trovato principalmente nel ginseng, in particolare nel Panax ginseng. È noto per le sue potenziali proprietà farmacologiche, inclusi effetti antinfiammatori, antiossidanti e anticancro. Ginsenoside Rg3 esiste in due forme isomeriche, Rg3(S) e Rg3(R), che possono mostrare diverse attività biologiche. Il composto ha una struttura molecolare complessa caratterizzata da uno scheletro simile a uno steroide con più gruppi idrossilici, contribuendo alla sua solubilità e reattività. Ginsenoside Rg3 è spesso studiato per il suo ruolo nel migliorare la funzione immunitaria e i suoi potenziali effetti neuroprotettivi. Inoltre, è stato indagato per la sua capacità di modulare diverse vie di segnalazione, rendendolo un argomento di interesse sia nella medicina tradizionale che nella farmacologia moderna. Il suo profilo di sicurezza e il potenziale terapeutico continuano a essere esplorati in studi clinici e preclinici, evidenziando la sua rilevanza nella salute e nel benessere.

Formula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1

InChI key: InChIKey=RWXIFXNRCLMQCD-JBVRGBGGSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Sinonimi:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20(S)-Ginsenoside-Rg₃
• 20(S)-Rg3
• 20S-Ginsenoside Rg3
• 3-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranosyldammar-24-ene-3β,12β,20S-triol
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Eta-D-Glucopyranosyl-
• Ginsenoside 20-Rg3
• Ginsenoside Rg3s
• Ginsenoside Rg₃
• Opyransoyl)Oxy)-
• S-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-
• Dammarane, β-D-glucopyranoside deriv.
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 785.03

Ref: 3B-G0568

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside Rg3 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₂H₇₂O₁₃

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 785.03

Ref: 11-0152S

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3

Purezza: ≥98%

Peso molecolare: 785.01g/mol

Ref: 54-BUP13475

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells, and the mechanism of their antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity.

Formula: C₄₂H₇₂O₁₃

Purezza: 95%~99%

Colore e forma: White powder

Peso molecolare: 785.025

Ref: BP-BP0666

Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Peso molecolare: 785.03

Ref: 4Z-G-157004

Ginsenoside Rg3-d6

CAS: 14197-60-5

Formula: C₄₂H₆₆D₆O₁₃

Peso molecolare: 791.06

Ref: 4Z-G-157008

Ginsenoside Rg3

CAS: 14197-60-5

Formula: C₄₂H₇₂O₁₃

Purezza: ≥ 98.0%

Colore e forma: White to beige powder

Peso molecolare: 785.01

Ref: 7W-GC4250

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.

Formula: C₄₂H₇₂O₁₃

Purezza: 98.11% - 99.93%

Colore e forma: Solid

Peso molecolare: 785.01

Ref: TM-T3402

Ginsenoside rg3

CAS: 14197-60-5

Natural glycoside

Formula: C₄₂H₇₂O₁₃

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 785.03

Ref: 5G-89681

Ginsenoside Rg3

Prodotto controllato

CAS: 14197-60-5

Applications Ginsenoside Rg3 shows a synergistic antitumor effect with cisplatin in cisplatin-resistant bladder tumor cell lines and is considered to be an anti-tumor agent.
References Lee, Y; et al.: Onc. Rep., 32, 1803 (2014); Ge, X. et al.: J. Int. Med. Res., 42, 628 (2014)

Formula: C₄₂H₇₂O₁₃

Colore e forma: Neat

Peso molecolare: 785.01

Ref: TR-G387590

(20S)-Ginsenoside Rg3

CAS: 14197-60-5

(20S)-Ginsenoside Rg3 is a bioactive saponin compound derived from the root of Panax ginseng. It is a naturally occurring component in ginseng, a traditional medicinal plant extensively studied for its diverse health benefits. The mode of action of (20S)-Ginsenoside Rg3 primarily involves the modulation of cellular pathways, such as the inhibition of tumor growth through apoptosis induction and anti-angiogenic effects. Additionally, it interacts with various signaling molecules, leading to its anti-inflammatory, antioxidant, and neuroprotective activities.

Formula: C₄₂H₇₂O₁₃

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 785.01 g/mol

Ref: 3D-OG09291