CAS 1421-65-4

L-3,4-diidrossifenilalanina metil*estere cloridrato

Descrizione:

L-3,4-diidrossifenilalanina metilestere cloridrato, comunemente noto come metilestere L-DOPA, è un derivato dell'aminoacido L-DOPA, che è un precursore di neurotrasmettitori come la dopamina. Questo composto è caratterizzato dai suoi gruppi idrossilici sul anello benzenico, che contribuiscono alla sua reattività e solubilità in solventi polari. La presenza del gruppo estere metilico aumenta la sua lipofilia rispetto a L-DOPA, potenzialmente influenzando la sua assorbimento e biodisponibilità. Come sale cloridrato, è tipicamente più stabile e solubile in soluzioni acquose, rendendolo adatto per varie applicazioni farmaceutiche. L-DOPA e i suoi derivati sono studiati principalmente per il loro ruolo nel trattamento di condizioni come il morbo di Parkinson, dove la carenza di dopamina è una preoccupazione significativa. Le proprietà farmacologiche del composto, inclusa la sua capacità di attraversare la barriera emato-encefalica, lo rendono un focus critico nella neurofarmacologia. Inoltre, la sua sintesi e caratterizzazione sono di interesse nella chimica medicinale per lo sviluppo di nuovi agenti terapeutici.

Formula: C₁₀H₁₄ClNO₄

InChI: InChI=1/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H

InChI key: InChIKey=WFGNJLMSYIJWII-FJXQXJEOSA-N

SMILES: C([C@@H](C(OC)=O)N)C1=CC(O)=C(O)C=C1.Cl

Sinonimi:

• (S)-Dopa methyl ester hydrochloride
• (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• 3,4-Dihydroxyphenyl-<span class="text-smallcaps">L</span>-alanine methyl ester hydrochloride
• 3-Hydroxy-<span class="text-smallcaps">L</span>-tyrosine methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Dopa methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• L-DOPA Me ester hydrochloride
• Levodopa methyl ester hydrochloride
• Methyl 3-Hydroxytyrosinate
• Methyl 3-Hydroxytyrosinate Hydrochloride (1:1)
• Methyl <span class="text-smallcaps">L</span>-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• St 41769
• methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1)
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• 3,4-Dihydroxyphenyl-L-alanine methyl ester hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, L-
• L-3,4-Dihydroxyphenylalanine methyl ester
• Methyl L-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• -3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• Dihydroxyphenylalanine Methyl ester hydrochloride
• TIANFUCHEM--1421-65-4--High purity L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE in stock
• Nsc295453
• LevoMet Hydrochloride
• L-3,4-DIHYDROXYPHENYLALANINE METHYLESTER HYDROCHLO
• 3-Hydroxy-L-tyrosine Methyl Ester Hydrochloride
• L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride,>95%
• Melevodopa Hydrochloride
• H-PHE(3,4-DI-HYDROXY)-OME HCL
• METHYL L-DOPA HYDROCHLORIDE
• 3,4-
• Methyl 3-Hydroxy-L-tyrosine Hydrochloride
• [(2S)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]azanium
• 3-hydroxy- L-Tyrosine methyl ester, hydrochloride (1:1)
• Levodopa Impurity 10
• Melevodopa
• L-DOPA Methyl Ester Hydrochloride
• -Methyl 2-amino-3-(3,4-dihydroxyphenyl)
• methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• H-TYR(3-HYDROXY)-OME HCL
• methyldopa hydrochloride
• 3-(3,4-Dihydroxyphenyl)alanine Methyl Ester Hydrochloride
• 2-Amino-3-(3,4-dihydroxyphenyl)-propanoic acid methylester hydrochloride
• L
• 4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE
• 3,4-DIHYDROXY PHENYLALANINE METHYL ESTER HYDROCHLORIDE
• -
• 3,4-Dihydroxy-L-phenylalanine Methyl Ester Hydrochloride
• (S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride
• L-3,4-dihydroxyphenylalanine methyl*ester hydroch
• Dopamine, methyl ester

L-Dopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₃NO₄·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 247.68

Ref: 3B-D6060

L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)

CAS: 1421-65-4

Formula: C₁₀H₁₄ClNO₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 247.6755

Ref: IN-DA001HT2

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

CAS: 1421-65-4

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

Purezza: 98%

Peso molecolare: 247.68g/mol

Ref: 54-OR1013624

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₃NO₄·HCl

Purezza: ≥ 98.0%

Colore e forma: Conflicting attributes defined

Peso molecolare: 247.68

Ref: 7W-GK2381

Levodopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Colore e forma: Neat

Ref: 86-MM0262.18

L-DOPA methyl ester (hydrochloride)

CAS: 1421-65-4

L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.

Formula: C₁₀H₁₄ClNO₄

Purezza: 98.69% - 99.81%

Colore e forma: White Solid

Peso molecolare: 247.675

Ref: TM-T7654

L-DOPA Methyl Ester Hydrochloride

Prodotto controllato

CAS: 1421-65-4

Applications L-DOPA Methyl Ester Hydrochloride is a selective Dopamine D1 receptor agonist (1,2,3).
References (1) Astradsson, A., et al.: Neurobiol. Dis., 35, 348 (2009)(2) Garcia-Molina, F., et al.: J. Agric. Food Chem., 57, 1143 (2009) (3) Giorgioni, G., et al.: Bioorg. Med. Chem., 18, 1834 (2010)

Formula: C₁₀H₁₃NO₄·ClH

Colore e forma: Neat

Peso molecolare: 247.68

Ref: TR-D533770

L-DOPA methyl ester hydrochloride

Prodotto controllato

CAS: 1421-65-4

L-DOPA methyl ester hydrochloride is a form of L-dopa that is used to treat Parkinson's disease. It is a prodrug of L-dopa, which has been shown to have a pharmacokinetic profile similar to that of levodopa. L-DOPA methyl ester hydrochloride is administered orally and is released slowly into the blood stream over time. This drug has been shown to interact with other drugs, such as antidepressants and antipsychotics, through its effects on neurotransmitters. In addition, this drug may cause locomotor activity in animals and can cause an increase in levels of dehydroascorbic acid in patients with chronic oral administration.

Formula: C₁₀H₁₃NO₄•HCl

Purezza: Min. 96 Area-%

Colore e forma: Powder

Peso molecolare: 247.68 g/mol

Ref: 3D-FD22596

(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

CAS: 1421-65-4

Formula: C₁₀H₁₄ClNO₄

Purezza: 98%

Colore e forma: Liquid, No data available.

Peso molecolare: 247.68

Ref: 10-F223023