CAS 142217-77-4

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxi)-9H-purina-9-il)-3-(benzyloxi)-2-(benzyloximetil)cilopentanolo

Descrizione:

La sostanza chimica con il nome "(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxi)-9H-purina-9-il)-3-(benzyloxi)-2-(benzyloximetil)cilopentanolo" e numero CAS "142217-77-4" è un composto organico complesso caratterizzato dai suoi gruppi multifunzionali e dalla stereochimica. Presenta un nucleo di ciclopentanol, che è un alcol ciclico a cinque membri, ed è sostituito da più gruppi benzyloxi, aumentando la sua lipofilia e il potenziale di attività biologica. La presenza di un gruppo amminico e di un derivato della purina suggerisce che questo composto possa mostrare proprietà rilevanti per la chimica degli acidi nucleici o fungere da potenziale agente farmaceutico. La stereochimica specifica indicata dalla configurazione (1S,2S,3S,5S) implica che il composto ha disposizioni spaziali definite, che possono influenzare significativamente la sua reattività e interazione con obiettivi biologici. In generale, la complessità strutturale di questo composto e i suoi gruppi funzionali suggeriscono potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di terapie mirate a processi legati agli acidi nucleici.

Formula: C₃₂H₃₃N₅O₄

InChI: InChI=1/C32H33N5O4/c33-32-35-30-28(31(36-32)41-19-24-14-8-3-9-15-24)34-21-37(30)26-16-27(40-18-23-12-6-2-7-13-23)25(29(26)38)20-39-17-22-10-4-1-5-11-22/h1-15,21,25-27,29,38H,16-20H2,(H2,33,35,36)/t25-,26+,27+,29+/m1/s1

Sinonimi:

• (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cydopentanol
• Entecavir intermediate N4
• (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((4-methylbenzyloxy)methyl)cyclopentanol
• Ent-4
• Intermediate of Entecavir 2
• (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxyl)-9H-purin-9yl)-3-(benzyloxymethyl)cyclopentanol
• (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)  cyclopentanol

Cyclopentanol, 5-[2-amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)-

CAS: 142217-77-4

Formula: C₃₂H₃₃N₅O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 551.6355

Ref: IN-DA001HZM

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

CAS: 142217-77-4

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

Purezza: 98%

Ref: 54-OR1037754

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

CAS: 142217-77-4

Purezza: 97%

Peso molecolare: 551.64697265625

Ref: 10-F692827

Entecavir Impurity 36

CAS: 142217-77-4

Formula: C₃₂H₃₃N₅O₄

Peso molecolare: 551.65

Ref: 4Z-E-2357

(2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol

Prodotto controllato

CAS: 142217-77-4

Applications (2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol is an intermediate in the preparation of ent-Entecavir (E558905).

Formula: C₃₂H₃₃N₅O₄

Colore e forma: Neat

Peso molecolare: 551.635

Ref: TR-A600160

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

CAS: 142217-77-4

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol is a synthetic compound that is used to treat patients with chronic myeloid leukemia. It has been shown to inhibit tyrosine kinase and interacts with the guanine binding site of the purine nucleoside phosphorylase. This drug also inhibits the enzyme (deoxy)ribonucleotide reductase and competes with adenosine for binding to adenosine receptors. The stereoisomers of this drug are active against chronic myeloid leukemia cells. The S enantiomer is more potent than the R enantiomer and exhibits greater selectivity for leukemic cells than healthy cells. It has also been shown to inhibit nitric oxide synthase and may have anti-

Formula: C₃₂H₃₃N₅O₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 551.64 g/mol

Ref: 3D-NA32025

Entecavir Impurity 18

CAS: 142217-77-4

Formula: C₃₂H₃₃N₅O₄

Peso molecolare: 551.65

Ref: ST-EA-CP-E36023