CAS 1430213-30-1

ML216

CAS: 1430213-30-1

Formula: C₁₅H₉F₄N₅OS

Purezza: %

Colore e forma: Solid

Peso molecolare: 383.3235

Ref: IN-DA009CDG

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

CAS: 1430213-30-1

1-(4-Fluoro-3-(Trifluoromethyl)Phenyl)-3-(5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Yl)Urea

Purezza: 98%

Peso molecolare: 383.32g/mol

Ref: 54-PC108707

ML216

CAS: 1430213-30-1

ML216

Purezza: ≥95%

Peso molecolare: 383.32g/mol

Ref: 54-BUP06162

ML216

CAS: 1430213-30-1

ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).

Formula: C₁₅H₉F₄N₅OS

Purezza: 98.12%

Colore e forma: Solid

Peso molecolare: 383.32

Ref: TM-T5413

ML-216

Prodotto controllato

CAS: 1430213-30-1

Applications ML-216 is a small molecule inhibitor of Bloom (BLM) helicase.
References Rosenthal, A., et al.: Bioorg. Med. Chem. Lett., 23, 5660 (2013); Nguyen, G., et al.: Chem. Biol., 20, 55(2013)

Formula: C₁₅H₉F₄N₅OS

Colore e forma: Neat

Peso molecolare: 383.324

Ref: TR-M425095

ML216

CAS: 1430213-30-1

ML216 is a chemotherapeutic drug that inhibits the repair mechanism of prostate cancer cells. It binds to leukocyte antigen (LFA-1) on the surface of tumor cells, and blocks the activity of suppressor genes that regulate the growth and development of these cells. ML216 has been shown to be active against prostate cancer cell lines in vitro and in vivo studies. This drug also has membrane permeability and anticancer activity.

Formula: C₁₅H₉F₄N₅OS

Purezza: Min. 95%

Peso molecolare: 383.32 g/mol

Ref: 3D-FHC21330