CAS 143824-78-6

Fmoc-L-Trp(Boc)-OH

Descrizione:

Fmoc-L-Trp(Boc)-OH, noto anche come 9-fluorenilmetossicarbonile-L-triptofano (Boc)-OH, è un amminoacido protetto comunemente utilizzato nella sintesi di peptidi. Presenta un gruppo fluorenilmetossicarbonile (Fmoc), che funge da gruppo protettivo per la funzionalità amminica, consentendo una desprotezione selettiva durante la sintesi. La presenza del gruppo Boc (tert-butilossicarbonile) nella catena laterale di indolo del triptofano ne migliora ulteriormente la stabilità e la solubilità nei solventi organici, rendendolo adatto per la sintesi di peptidi in fase solida. Questo composto è tipicamente bianco a bianco sporco nell'aspetto ed è solubile in solventi organici come dimetilformammide (DMF) e dimetilsolfossido (DMSO), ma meno solubile in acqua. La sua struttura molecolare include uno scheletro di triptofano, che contribuisce alle sue proprietà uniche, come la fluorescenza e la capacità di partecipare a interazioni di stacking π-π. Fmoc-L-Trp(Boc)-OH è ampiamente utilizzato nella sintesi di peptidi e proteine, in particolare in applicazioni di ricerca e farmaceutiche, grazie alla sua capacità di facilitare l'introduzione di residui di triptofano nelle catene peptidiche.

Formula: C₃₁H₃₀N₂O₆

InChI: InChI=1S/C31H30N2O6/c1-31(2,3)39-30(37)33-17-19(20-10-8-9-15-27(20)33)16-26(28(34)35)32-29(36)38-18-25-23-13-6-4-11-21(23)22-12-5-7-14-24(22)25/h4-15,17,25-26H,16,18H2,1-3H3,(H,32,36)(H,34,35)/t26-/m0/s1

InChI key: InChIKey=ADOHASQZJSJZBT-SANMLTNESA-N

SMILES: C(OC(N[C@@H](CC=1C=2C(N(C(OC(C)(C)C)=O)C1)=CC=CC2)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinonimi:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
• 1-(tert-butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tryptophan
• 3-[(2S)-2-Carboxy-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]ethyl]indole-1-carboxylic acid tert-butyl ester
• <span class="text-smallcaps">L</span>-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Trp(Boc)-OH
• Fmoc-Trp(Boc)
• Fmoc-Trp(Boc)-OH
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-in-t-butyl-oxycarbonyl-L-tryptophan
• N-α-Fmoc-N(in)-Boc-L-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan

1-Boc-N-Fmoc-L-tryptophan, 97%

CAS: 143824-78-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₁H₃₀N₂O₆

Purezza: 97%

Peso molecolare: 526.59

Ref: 02-H59663

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Sold under license to US Pat. 5,300,651 and EP 0 516 070. The use of this protected tryptophan derivative in Fmoc solid-phase peptide synthesis resulted in an improved yield of the correct product by suppressing side reactions of tryptophan.

Formula: C₃₁H₃₀N₂O₆

Purezza: 99.47%

Colore e forma: White

Peso molecolare: 526.59

Ref: 01-4017674

L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 143824-78-6

Formula: C₃₁H₃₀N₂O₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 526.5797

Ref: IN-DA001IFQ

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

M03376 - Fmoc-Trp(Boc)-OH

Formula: C₃₁H₃₀N₂O₆

Purezza: 95%

Colore e forma: Solid, Crystalline or Powder

Peso molecolare: 526.589

Ref: 10-M03376

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan

CAS: 143824-78-6

Formula: C₃₁H₃₀N₂O₆

Purezza: >97.0%(HPLC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 526.59

Ref: 3B-F0507

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH

Formula: C₃₁H₃₀N₂O₆

Purezza: 98%

Colore e forma: white to light beige powder

Peso molecolare: 526.58g/mol

Ref: 54-OR350178

Fmoc-L-Trp(Boc)-OH

CAS: 143824-78-6

Formula: C₃₁H₃₀N₂O₆

Peso molecolare: 526.59

Ref: 4Z-T-2083

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Formula: C₃₁H₃₀N₂O₆

Purezza: ≥ 98.0%

Colore e forma: White to almost white powder

Peso molecolare: 526.58

Ref: 7W-GM7354

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH is an amide that has been shown to have the ability to bind to human serum proteins, making it useful in clinical diagnostics. This compound has also been found to be effective against a variety of bacterial strains and fungi. The Fmoc-Trp(Boc)-OH peptide can be synthesized using solid-phase synthesis techniques, which involve attaching amino acid residues to a polymer support. This process is cell specific and allows for the production of peptides with specific sequences. The presence of histidine residues on the side chain of this molecule makes it a good candidate for use in antimicrobial peptides.

Formula: C₃₁H₃₀N₂O₆

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 526.58 g/mol

Ref: 3D-FF15878

Fmoc-Trp(Boc)-OH-13C11,15N2

Prodotto controllato

CAS: 143824-78-6

Formula: C₁₁C₂₀H₃₀₁₅N₂O₆

Colore e forma: Neat

Peso molecolare: 539.486

Ref: TR-F679602

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH is a building block for the synthesis of peptides and other bioactive molecules. It is used in the synthesis of daptomycin, an antibiotic that is used to treat bacterial infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Fmoc-Trp(Boc)-OH is also used as a synthon in the production of natural products such as kynurenine, which has been shown to have anti-cancer properties.

Formula: C₃₁H₃₀N₂O₆

Purezza: Min. 95%

Peso molecolare: 526.59 g/mol

Ref: 3D-FLW-1769-PI