CAS 144143-96-4

Acido 2-tiofenpropanoico, α-[[2-butil-1-[(4-carbossifenil)metil]-1H-imidazol-5-il]metilene]-, (αE)-, metansulfonato (1:1)

Descrizione:

Acido 2-tiofenpropanoico, α-[[2-butil-1-[(4-carbossifenil)metil]-1H-imidazol-5-il]metilene]-, (αE)-, metansulfonato (1:1) è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, inclusi un anello di tiofeno e una parte di imidazolo. Questo composto presenta proprietà sia acide che basiche grazie alla presenza di funzioni di acido carbossilico e imidazolo, che possono partecipare a varie reazioni chimiche, inclusi il trasferimento di protoni e la coordinazione con ioni metallici. Il gruppo metansolfonato migliora la sua solubilità in solventi polari, rendendolo adatto per varie applicazioni nella sintesi organica e nella chimica medicinale. Inoltre, la presenza dei gruppi butile e fenile contribuisce alle sue caratteristiche idrofobiche, influenzando la sua attività biologica e interazione con obiettivi cellulari. La stereochimica del composto, indicata dalla designazione (αE), suggerisce disposizioni spaziali specifiche che possono influenzare la sua reattività e proprietà di legame. In generale, questa sostanza è di interesse nella ricerca farmaceutica, in particolare per le sue potenziali applicazioni terapeutiche.

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

InChI: InChI=1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;

InChI key: InChIKey=DJSLTDBPKHORNY-XMMWENQYSA-N

SMILES: C(N1C(/C=C(\CC2=CC=CS2)/C(O)=O)=CN=C1CCCC)C3=CC=C(C(O)=O)C=C3.S(C)(=O)(=O)O

Sinonimi:

• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (E)-, monomethanesulfonate
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, monomethanesulfonate
• 4-({2-butyl-5-[(1E)-2-carboxy-3-thiophen-2-ylprop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid methanesulfonate
• 4-[[2-Butyl-5-(2-Carboxy-3-Thiophen-2-Yl-Prop-1-Enyl)-Imidazol-1-Yl]Methyl]Benzoic Acid Mesylate
• Eprosartan Methanesulfonate
• Skf 108566J
• Eprosartan mesylate

Eprosartan Mesylate

CAS: 133040-01-4, 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 520.62

Ref: 3B-E1161

Eprosartan Mesylate ((E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid, monomethanesulfonate)

CAS: 144143-96-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Colore e forma: White Crystalline Powder

Peso molecolare: 424.14568

Ref: 45-1238217

4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; methanesulfonic acid

CAS: 144143-96-4

Formula: C₂₄H₂₈N₂O₇S₂

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 520.6183

Ref: IN-DA001IZZ

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Purezza: 99%

Peso molecolare: 520.62g/mol

Ref: 54-OR1028758

Eprosartan Mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 424.52 96.11

Ref: 4Z-E-151

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Purezza: ≥98%

Peso molecolare: 520.62g/mol

Ref: 54-BUP15659

Eprosartan mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Peso molecolare: 520.62

Ref: 7W-GP8368

Eprosartan mesylate

Prodotto controllato

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Colore e forma: Neat

Peso molecolare: 520.62

Ref: 04-C13188000

Eprosartan Mesilate

Prodotto controllato

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Colore e forma: Neat

Peso molecolare: 520.62

Ref: 86-MM1577.00

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Purezza: 99.72% - 99.93%

Colore e forma: A White To Off- White Powder

Peso molecolare: 520.62

Ref: TM-T2531

Eprosartan Mesylate

Prodotto controllato

CAS: 144143-96-4

Applications Eprosartan Mesylate is an angiotensin II receptor antagonists. Eprosartan Mesylate is used as an antihypertensive agent.
References Sheng, J. et al.: J. Pharmac. Sci., 88., 1021 (1999); Punzi, H.A. et al.: J. Hum. Hypertens., 18, 655 (2004);

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Colore e forma: Neat

Peso molecolare: 520.62

Ref: TR-E590105

Eprosartan mesylate

CAS: 144143-96-4

Eprosartan mesylate is an angiotensin II receptor antagonist and a prodrug of eprosartan. It is used in the treatment of hypertension, congestive heart failure, and for the prophylaxis of organ rejection in renal transplantation. This drug has been shown to inhibit the activation of nuclear factor-κB (NF-κB) and the production of inflammatory cytokines such as growth factor-β1 (GF-β1). Eprosartan mesylate has also been shown to have a beneficial effect on experimental models of type 2 diabetes and metabolic disorders. In clinical trials, it was found that losartan had similar effects on lowering blood pressure as eprosartan mesylate, but the combination increased blood pressure more than either agent alone. Eprosartan mesylate should not be taken with drugs that are metabolized by cytochrome P450 enzymes because they may lead to serious adverse effects such

Formula: C₂₃H₂₄N₂O₄S•CH₄O₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 520.62 g/mol

Ref: 3D-FE61516

Eprosartan Mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄SCH₄O₃S

Peso molecolare: 424.52 : 96.1

Ref: ST-EA-CP-E64008