CAS 144689-63-4

olmesartan medoxomil

Descrizione:

olmesartan medoxomil è un antagonista del recettore dell'angiotensina II utilizzato principalmente nel trattamento dell'ipertensione. È un pro-farmaco, il che significa che viene metabolizzato nel corpo nella sua forma attiva, olmesartan. La sostanza è caratterizzata dalla sua capacità di bloccare selettivamente il recettore dell'angiotensina II di tipo 1 (AT1), che gioca un ruolo cruciale nella regolazione della pressione sanguigna e dell'equilibrio dei fluidi. Chimicamente, olmesartan medoxomil è una polvere cristallina bianca o bianco sporco che è praticamente insolubile in acqua ma solubile in solventi organici. La sua formula molecolare riflette una struttura complessa che include un gruppo bifenile, contribuendo alla sua attività farmacologica. Il composto presenta una lunga emivita, consentendo una somministrazione una volta al giorno, ed è spesso ben tollerato con un profilo di effetti collaterali favorevole. Inoltre, olmesartan medoxomil è stato associato a effetti protettivi renali, rendendolo un'opzione preziosa nella gestione dei pazienti con ipertensione, in particolare quelli con condizioni comorbide.

Formula: C₂₄H₂₆N₆O₃

InChI: InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

InChI key: InChIKey=UQGKUQLKSCSZGY-UHFFFAOYSA-N

SMILES: C(N1C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(C)(C)O)N=C1CCC)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Sinonimi:

• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate
• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}imidazaole-5-carboxylate
• (5-Methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-ethyl-2-propyl-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl.5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
• 1,3-Dioxole, 1H-imidazole-5-carboxylic acid deriv.
• 1H-Imidazole-5-Carboxylic Acid, 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-, (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 2-Butyl-4-(1-hydroxy-1-methylethyl)-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• Angiosartan
• Benicar
• Cs-866
• Medoxomil
• Olmesartan Medoximil
• Olmetec
• Olsertain
• Omst
• Olmesartan medoxomil
• 5-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-3-[2''-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-IMIDAZOLE-4-CARBOXYLIC ACID 5-METHYL-2-OXO-[1,3]DIOXOL-4-YLMETHYL ESTER
• CS-866, 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2(1H-tetazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
• 5-(1-Hydroxy-1-methylethyl)-2-propyl-3-[2'-(1H-tet
• OlmesartanC29H30N6O6
• OLMESARTAN
• 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid(5-Methyl-2-oxo-1,3-dioxol-4-yl)methylester

Olmesartan Medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 558.60

Ref: 3B-O0510

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan medoxomil

Formula: C₂₉H₃₀N₆O₆

Purezza: 99.7%

Colore e forma: White. To. Light Yellow

Peso molecolare: 558.22268

Ref: 47-1173

OLMESARTAN MEDOXOMIL CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL CRS

Formula: C₂₉H₃₀N₆O₆

Colore e forma: Powder

Peso molecolare: 558.5851

Ref: 41-Y0001405

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

Formula: C₂₉H₃₀N₆O₆

Colore e forma: Powder

Peso molecolare: 558.5851

Ref: 41-Y0001424

Olmesartan Medoxomil

CAS: 144689-63-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₉H₃₀N₆O₆

Colore e forma: White Light Yellow Powder

Peso molecolare: 558.22268

Ref: 45-1478367

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 558.5851

Ref: IN-DA001K0D

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.

Formula: C₂₉H₃₀N₆O₆

Purezza: 99.89% - 99.9%

Colore e forma: White To Off-White Crystalline Powder

Peso molecolare: 558.59

Ref: TM-T1518

Olmesartan Medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 558.60

Ref: 4Z-O-083

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Purezza: ≥98%

Peso molecolare: 558.59g/mol

Ref: 54-BUP15452

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Purezza: 99%

Peso molecolare: 558.59g/mol

Ref: 54-OR1030127

Olmesartan medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purezza: 98.0 - 102.0 % (dried basis)

Colore e forma: White to almost white powder

Peso molecolare: 558.59

Ref: 7W-GP3934

Olmesartan medoxomil, EP grade

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Peso molecolare: 558.59

Ref: 7W-GP8971

Olmesartan Medoxomil

Prodotto controllato

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Colore e forma: Neat

Peso molecolare: 558.59

Ref: 86-MM1317.00

Olmesartan Medoxomil RS

CAS: 144689-63-4

Colore e forma: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1034800021

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan is a drug that belongs to the class of angiotensin II receptor antagonists. It is used for the treatment of high blood pressure, heart failure, and kidney disease. The therapeutic effect of olmesartan can be increased by concomitant use with other drugs if it is being used as a combination therapy. This drug interacts with many other drugs, including diuretics and ACE inhibitors. Drugs that are known to interact with olmesartan include furosemide, hydrochlorothiazide, amiloride, spironolactone, triamterene, chlorothiazide and quinethazone. Blood sampling is often required during therapy in order to monitor the efficacy of this drug.

Formula: C₂₉H₃₀N₆O₆

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 558.59 g/mol

Ref: 3D-IH57934

Olmesartan Medoxomil

Prodotto controllato

CAS: 144689-63-4

Applications An angiotensin II receptor antagonist. Used as an anti-hypertensive.
References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996), Puchler, K., et al.: J. Hypertens., 15, 1809 (1997),

Formula: C₂₉H₃₀N₆O₆

Colore e forma: White

Peso molecolare: 558.59

Ref: TR-O550000

Olmesartan Medoxomil

CAS: 144689-63-4

Colore e forma: Neat

Ref: 61-FOR1317.00