CAS 1447-88-7

Hispidulina

Descrizione:

Hispidulina è un composto flavonoide che si verifica naturalmente, classificato nella categoria delle flavone. È principalmente derivato da varie fonti vegetali, in particolare da quelle della famiglia Asteraceae. La struttura chimica di Hispidulina presenta uno scheletro di cromone, caratteristico dei flavonoidi, e include gruppi idrossilici che contribuiscono alla sua attività biologica. Questo composto è noto per le sue potenziali proprietà antiossidanti, antinfiammatorie e neuroprotettive, rendendolo di interesse nella ricerca farmacologica. Inoltre, Hispidulina è stato studiato per i suoi effetti su vari percorsi cellulari, suggerendo potenziali applicazioni terapeutiche in condizioni come il cancro e le malattie neurodegenerative. La sua solubilità e stabilità possono variare a seconda del solvente e delle condizioni ambientali, il che è importante per la sua applicazione sia nella ricerca che nel potenziale uso medicinale. In generale, Hispidulina rappresenta un'area significativa di studio all'interno della chimica dei prodotti naturali, con ricerche in corso volte a chiarire i suoi meccanismi d'azione e i potenziali benefici per la salute.

Formula: C₁₆H₁₂O₆

InChI: InChI=1/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3

InChI key: InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(O)=C1OC

Sinonimi:

• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
• 4′,5,7-Trihydroxy-6-methoxyflavone
• 5,7,4′-Trihydroxy-6-methoxyflavone
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
• 6-Methoxy-5,7,4′-trihydroxyflavone
• 6-Methoxyapigenin
• 6-Methylscutellarein
• 6-O-Methylscutellarein
• Dinatin
• Flavone, 4′,5,7-trihydroxy-6-methoxy-
• Hispedulin
• Hispiludin
• NSC 122415
• Salvitin
• Scutellarein 6-Methyl Ether
• Hispidulin
• Hispidulin, >99%
• 1447-88-7
• Hispidulin(Dinatin)
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
• 4',5,7-Trihydroxy-6-methoxyflavone

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₆H₁₂O₆

Purezza: (HPLC) ≥95%

Colore e forma: Powder

Peso molecolare: 300.27

Ref: 11-1451

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 300.2629

Ref: IN-DA001K12

Hispidulin

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Peso molecolare: 300.27

Ref: 7W-GY8195

Hispidulin

CAS: 1447-88-7

Hispidulin

Purezza: ≥95%

Peso molecolare: 300.26g/mol

Ref: 54-BUP17580

Hispidulin

CAS: 1447-88-7

Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1.

Formula: C₁₆H₁₂O₆

Purezza: 95%~99%

Peso molecolare: 300.266

Ref: BP-BP0730

Hispidulin

CAS: 1447-88-7

Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).

Formula: C₁₆H₁₂O₆

Purezza: 98.53% - 99.87%

Colore e forma: Solid

Peso molecolare: 300.26

Ref: TM-TQ0201

Hispidulin

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Peso molecolare: 300.27

Ref: 4Z-H-031001

Hispidulin

CAS: 1447-88-7

Oxygen-heterocyclic compound

Formula: C₁₆H₁₂O₆

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 300.27

Ref: 5G-83335

Hispidulin

CAS: 1447-88-7

Hispidulin is a naturally occurring flavonoid compound, which is predominantly derived from plants such as Salvia and Artemisia species. This bioactive compound exhibits a broad spectrum of pharmacological activities that have garnered attention in the scientific community. Its mode of action involves the modulation of cellular pathways, including the inhibition of enzymes like cyclooxygenases, which are pivotal in inflammatory responses. Furthermore, Hispidulin has been shown to influence neurotransmitter systems, including GABAergic activity, indicating potential neuroprotective effects.

Formula: C₁₆H₁₂O₆

Purezza: Min. 98 Area-%

Colore e forma: Off-White Powder

Peso molecolare: 300.26 g/mol

Ref: 3D-FH73251

Hispidulin - Bio-X ™

CAS: 1447-88-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₆H₁₂O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 300.26 g/mol

Ref: 3D-BH300089

Hispidulin

CAS: 1447-88-7

Purezza: 99%

Peso molecolare: 300.2659912

Ref: 10-F814360

Hispidulin

Prodotto controllato

CAS: 1447-88-7

Applications Hispidulin is a potent benzodiazepine (BZD) receptor ligand.

Formula: C₁₆H₁₂O₆

Colore e forma: Neat

Peso molecolare: 300.27

Ref: TR-H456340

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₆H₁₂O₆

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 300.27

Ref: 11-1451S