CAS 145108-58-3

cloridrato di dexmedetomidina

Descrizione:

Il cloridrato di dexmedetomidina (CAS 145108-58-3) è un agonista selettivo dei recettori adrenergici alfa-2, utilizzato principalmente per le sue proprietà sedative e analgesiche in contesti clinici, in particolare nelle unità di terapia intensiva e durante le procedure chirurgiche. È caratterizzato dalla sua capacità di indurre sedazione senza causare una significativa depressione respiratoria, rendendolo una scelta preferita per i pazienti che richiedono sedazione mantenendo i riflessi delle vie aeree. Il composto viene tipicamente somministrato per via endovenosa e ha un rapido inizio d'azione, con effetti che possono essere invertiti mediante la somministrazione di antagonisti specifici. La dexmedetomidina mostra un'alta affinità per i recettori adrenergici alfa-2, portando a una diminuzione del rilascio di norepinefrina e risultando in sedazione, analgesia e ansiolitici. Il suo profilo farmacocinetico include una vita media relativamente breve, che consente rapidi aggiustamenti nei livelli di sedazione. Inoltre, è importante notare che la dexmedetomidina può avere effetti cardiovascolari, inclusi bradicardia e ipotensione, richiedendo un attento monitoraggio durante la somministrazione. In generale, il cloridrato di dexmedetomidina è apprezzato per le sue uniche proprietà sedative e il profilo di sicurezza in varie applicazioni mediche.

Formula: C₁₃H₁₇ClN₂

InChI: InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1

InChI key: InChIKey=VPNGEIHDPSLNMU-MERQFXBCSA-N

SMILES: [C@H](C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2.Cl

Sinonimi:

• (S)-4-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride
• 1H-Imidazole, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride
• 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, monohydrochloride, (S)-
• 1H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)
• 4-((S)-Alpha,2,3-Trimethylbenzyl)Imidazole Monohydrochloride
• 4-[(1R)-1-(2,3-Dimethylphenyl)Ethyl]-3H-Imidazole Hydrochloride
• 5-[(1R)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1)
• 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole hydrochloride
• Cepedex
• Dexdomitor
• Dexdor
• Dexmedetomidine
• Dexmedetomidine Hydrochloride
• Dexmedetomidine(Pilot)
• Dexmetomidine
• Hydrochloride
• Precedex
• Sedadex
• Sileo
• demedetomidine HCL
• 4-[(1r)-1-(2,3-dimethylphenyl)ethyl]-3h-imidazolehydrochloride
• Dex

Dexmedetomidine Hydrochloride

CAS: 113775-47-6, 145108-58-3

Formula: C₁₃H₁₆N₂·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 236.74

Ref: 3B-D5062

Dexmedetomidine Hydrochloride

CAS: 145108-58-3

Colore e forma: Neat

Ref: 61-FOR3355.00

Dexmedetomidine Hydrochloride

CAS: 145108-58-3

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₁₃H₁₆N₂·HCl

Colore e forma: White Powder

Peso molecolare: 200.13135

Ref: 45-1179333

1H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1)

CAS: 145108-58-3

Formula: C₁₃H₁₇ClN₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 236.7405

Ref: IN-DA001KKV

Dexmedetomidine Hydrochloride

CAS: 145108-58-3

Dexmedetomidine Hydrochloride

Purezza: 99%

Peso molecolare: 236.74g/mol

Ref: 54-OR1025485

Dexmedetomidine hydrochloride

CAS: 145108-58-3

Dexmedetomidine hydrochloride

Purezza: ≥98%

Peso molecolare: 236.74g/mol

Ref: 54-BUP17795

Dexmedetomidine HCl

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂·HCl

Peso molecolare: 200.29 36.46

Ref: 4Z-D-291001

Dexmedetomidine hydrochloride, USP grade

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂·HCl

Purezza: ≤ 1.0% (of Levomedetomidine HCl)

Colore e forma: White to off-white powder

Peso molecolare: 236.74

Ref: 7W-GX7871

Dexmedetomidine Hydrochloride

Prodotto controllato

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂·ClH

Colore e forma: Neat

Peso molecolare: 236.74

Ref: 86-MM3355.00

Dexmedetomidine hydrochloride

CAS: 145108-58-3

Dexmedetomidine hydrochloride (Precedex) is a potent, selective, orally active α2-adrenoceptor agonist.Cost-effective and quality-assured.

Formula: C₁₃H₁₆N₂·HCl

Purezza: 99.94% - 99.94%

Colore e forma: White Or Almost White Crystalline Powder

Peso molecolare: 236.74

Ref: TM-T6466

Dexmedetomidine hydrochloride

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂·HCl

Colore e forma: White to beige powder

Peso molecolare: 236.74

Ref: 7W-GW7920

Dexmedetomidine Hydrochloride

Prodotto controllato

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂·ClH

Colore e forma: White To Off-White

Peso molecolare: 236.74

Ref: TR-D299008

Dexmedetomidine hydrochloride

Prodotto controllato

CAS: 145108-58-3

Dexmedetomidine hydrochloride is a drug that belongs to the class of drugs known as anesthetic agents. It is used to sedate patients before and during surgery or other procedures. Dexmedetomidine hydrochloride has shown clinical relevance in the treatment of diabetic neuropathy, with a reduction of pain and improvement in quality of life. It also has been shown to reduce postoperative ileus, which may be due to its ability to inhibit the release of inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Dexmedetomidine hydrochloride can be administered by intravenous or intramuscular injection. This drug does not have any effect on the cardiovascular system, although it does cause sedation and has been shown to increase heart rate. The drug is eliminated from the body through metabolism by cytochrome P450 enzymes in the liver, primarily CYP3A

Formula: C₁₃H₁₆N₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 236.74 g/mol

Ref: 3D-FD167004

Dexmedetomidine hydrochloride - Bio-X ™

Prodotto controllato

CAS: 145108-58-3

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₃H₁₆N₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 236.74 g/mol

Ref: 3D-FD37014

(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride

CAS: 145108-58-3

Formula: C₁₃H₁₇ClN₂

Purezza: 98%

Peso molecolare: 236.74

Ref: 10-F462701

Dexmedetomidine hydrochloride

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂HCl

Peso molecolare: 200.29 : 36.46

Ref: ST-EA-CP-D237000

Dexmedetomidine hydrochloride

CAS: 145108-58-3

Formula: C₁₃H₁₆N₂HCl

Peso molecolare: 200.29 : 36.46

Ref: ST-EA-CP-M8021