CAS 145435-72-9

Gamithromicina

Descrizione:

Gamithromicina è un antibiotico macrolide utilizzato principalmente in medicina veterinaria, in particolare per il trattamento delle infezioni respiratorie nel bestiame. È caratterizzato dalla sua attività antibatterica ad ampio spettro, che colpisce una varietà di batteri Gram-positivi e alcuni Gram-negativi. Gamithromicina agisce inibendo la sintesi proteica batterica legandosi alla subunità ribosomiale 50S, interrompendo efficacemente la crescita e la riproduzione dei batteri. Il composto è noto per la sua lunga emivita, che consente una somministrazione meno frequente rispetto ad altri antibiotici. Viene tipicamente somministrato per iniezione ed è preferito per la sua efficacia contro patogeni come le specie di Mycoplasma e Pasteurella. Inoltre, Gamithromicina ha un profilo di sicurezza favorevole quando usato secondo le indicazioni negli animali, sebbene il suo uso negli animali da reddito sia regolamentato per prevenire residui di antibiotici nei prodotti a base di carne. Come con tutti gli antibiotici, l'uso responsabile è cruciale per mitigare il rischio di sviluppare batteri resistenti agli antibiotici.

Formula: C₄₀H₇₆N₂O₁₂

InChI: InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1

InChI key: InChIKey=VWAMTBXLZPEDQO-UZSBJOJWSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Sinonimi:

• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• Gamithormycin
• Gamithromycin
• Ml 1709460
• Zactran
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

1-Oxa-7-azacyclopentadecan-15-one,13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-,[2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

CAS: 145435-72-9

Formula: C₄₀H₇₆N₂O₁₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 777.0376

Ref: IN-DA00HXF7

Gamithromycin

CAS: 145435-72-9

Formula: C₄₀H₇₆N₂O₁₂

Purezza: 95.0 - 103.0 % (dried basis)

Colore e forma: Light-yellow to off-white powder or solid

Peso molecolare: 777.04

Ref: 7W-GC5312

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

CAS: 145435-72-9

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

Purezza: 95%

Peso molecolare: 777.04g/mol

Ref: 54-OR1025800

Gamithromycin

CAS: 145435-72-9

Gamithromycin

Purezza: ≥98%

Peso molecolare: 777.04g/mol

Ref: 54-BUP14548

Gamithromycin 100 µg/mL in Methanol

Prodotto controllato

CAS: 145435-72-9

Formula: C₄₀H₇₆N₂O₁₂

Colore e forma: Single Solution

Peso molecolare: 777.04

Ref: 04-A13998500ME-100

Gamithromycin

Prodotto controllato

CAS: 145435-72-9

Formula: C₄₀H₇₆N₂O₁₂

Colore e forma: Neat

Peso molecolare: 777.04

Ref: 04-C13998500

Gamithromycin

CAS: 145435-72-9

Formula: C₄₀H₇₆N₂O₁₂

Peso molecolare: 777.05

Ref: 4Z-G-057003

Gamithromycin

CAS: 145435-72-9

Gamithromycin (ML-1709460) is a macrolide compound with antibacterial activity.

Formula: C₄₀H₇₆N₂O₁₂

Purezza: 99.38%

Colore e forma: Solid

Peso molecolare: 777.04

Ref: TM-T3629

Gamithromycin

Prodotto controllato

CAS: 145435-72-9

Stability Hygroscopic
Applications A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic.
References Broto, P., et al.: Eur. J. Med. Chem., 19, 71 (1984), Farrar, V., et al.: J. Med. Chem., 36, 3517 (1993), Clark, D., et al.: J. Pharm. Sci., 88, 807 (1999),

Formula: C₄₀H₇₆N₂O₁₂

Colore e forma: Neat

Peso molecolare: 777.04

Ref: TR-G195000

Gamithromycin

CAS: 145435-72-9

Gamithromycin is a macrolide antibiotic with action on bacterial protein synthesis and is used for treating respiratory infections in cattle, pigs, and sheep.

Formula: C₄₀H₇₆N₂O₁₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 777.04 g/mol

Ref: 3D-AG16733