CAS 146-22-5
:2H-1,4-Benzodiazepin-2-one, 1,3-diidro-7-nitro-5-fenile-
Descrizione:
2H-1,4-Benzodiazepin-2-one, 1,3-diidro-7-nitro-5-fenile- (CAS 146-22-5) è un composto chimico appartenente alla classe delle benzodiazepine, caratterizzato da una struttura ad anello fuso di benzene e diazepina. Questo composto presenta tipicamente una gamma di proprietà farmacologiche, inclusi effetti ansiolitici, sedativi e miorilassanti, sebbene la sua attività specifica possa variare in base alle modifiche strutturali. La presenza di un gruppo nitro in posizione 7 e di un gruppo fenile in posizione 5 contribuisce alla sua reattività chimica unica e al potenziale di attività biologica. In termini di proprietà fisiche, le benzodiazepine mostrano spesso una solubilità moderata nei solventi organici e una solubilità limitata in acqua, il che può influenzare la loro biodisponibilità e farmacocinetica. La struttura molecolare del composto consente interazioni con il sistema nervoso centrale, principalmente attraverso la modulazione dei recettori GABA, rendendolo di interesse nella chimica medicinale e nella farmacologia. Le precauzioni di sicurezza e di manipolazione sono essenziali a causa della potenziale tossicità e degli effetti collaterali associati ai derivati delle benzodiazepine.
Formula:C15H11N3O3
InChI:InChI=1/C18H17ClN2O/c1-11(2)16-18(22)20-15-9-8-13(19)10-14(15)17(21-16)12-6-4-3-5-7-12/h3-11,16H,1-2H3,(H,20,22)
InChI key:InChIKey=KJONHKAYOJNZEC-UHFFFAOYSA-N
SMILES:N(=O)(=O)C=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Sinonimi:- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepine-2-one
- 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
- 7-Nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- Benzalin
- Calsmin
- Dormicum
- Dormicum (anticonvulsant)
- Dormin 5
- Eatan
- Epibenzalin
- Epinelbon
- Eunoctin
- Hipnax
- Hipsal
- Imeson
- Insomin
- Ipersed
- La 1
- Megadon
- Mogadan
- Mogadon
- Mogadone
- N-Desmethylnimetazepam
- Nelbon
- Neozepam
- Neuchlonic
- Nipam
- Nitrados
- Nitravet
- Nitrazepam
- Nitrenpax
- Nitrosun
- Noctesed
- Nsc 58775
- Paxisyn
- Pelson
- Radedorm
- Relact
- Remnos
- Ro 4-5360
- Ro 5-3059
- Somitran
- Somnased
- Somnibel
- Somnite
- Sonebon
- Sonnolin
- Surem
- Unisomnia
- Xiaoxipan
- nitrazepam--dea schedule iv item
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl-
- 1,3-dihydro-7-nitro-5-phenyl-1,4-benzodiazepin-2-one
- 7-chloro-5-phenyl-3-(propan-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Apodorm
- 1H-1,4-Benzodiazepin-2(3H)-one, 7-chloro-3-isopropyl-5-phenyl-
- Cerson
- Eunoktin
- 7-Nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-dihydro-7-nitro-5-phenyl-2h-4-benzodiazepin-2-one
- Vedi altri sinonimi
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
13 prodotti.
Nitrazepam
CAS:Prodotto controllato<p>Applications Anticonvulsant; hypnotic.Controlled substance (depressant).<br>References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).<br></p>Formula:C15H11N3O3Colore e forma:White To Off-WhitePeso molecolare:281.27Nitrazepam
CAS:Prodotto controllato<p>Nitrazepam is a benzodiazepine with hypnotic and sedative properties. It binds to the GABA-A receptor in the brain, leading to an increase in the frequency of chloride ion channel opening. Nitrazepam has synergistic effects with other drugs such as antidepressants, antipsychotics, and antihistamines. It is used for the treatment of insomnia and anxiety disorders. Nitrazepam has been shown to have a rate constant of 0.068 L/mg at 25°C in human serum. This drug can be analyzed by gas chromatography following derivatization with methanol or ethyl acetate. Nitrazepam is one of many compounds found in wastewater that may cause long-term damage to the environment during wastewater treatment. The presence of nitrazepam in biological samples can be determined by a control analysis using a method that employs high performance liquid chromatography (HPLC). Nitrazepam can also be detected by polymerase chain reaction</p>Formula:C15H11N3O3Purezza:Min. 95%Colore e forma:SolidPeso molecolare:281.27 g/molNitrazepam
CAS:Prodotto controllato<p>Nitrazepam is a peptide that is used as a research tool for the study of ion channels and protein interactions. It has an affinity for GABA receptors and can be used to study the effects of receptor activation. Nitrazepam also binds to antibody-producing cells, which leads to increased production of antibodies by these cells. This drug is an inhibitor that blocks the binding of ligands to their receptors, thereby preventing or reversing the effects of ligand binding on cell function. Nitrazepam is a high-purity reagent with CAS No. 146-22-5, which can be used in life science research and cell biology.</p>Formula:C15H11N3O3Peso molecolare:281.27 g/molNITRAZEPAM CRS - * PSY
CAS:Prodotto controllato<p>NITRAZEPAM CRS - * PSY</p>Formula:C15H11N3O3Colore e forma:PowderPeso molecolare:281.2661Nitrazepam
CAS:Prodotto controllatoNitrazepamFormula:C15H11N3O3Purezza:100.0%Colore e forma:White To Off-WhitePeso molecolare:281.08004Nitrazepam (1.0 mg/mL in Acetonitrile)
CAS:Prodotto controllatoFormula:C15H11N3O3Colore e forma:ColourlessPeso molecolare:281.27Nitrazepam (100μg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C15H11N3O3Colore e forma:ColourlessPeso molecolare:281.27
