CAS 146-68-9

Cloruro di 2-(4-iodofenile)-3-(4-nitrofenile)-5-feniltetrazolio idrato

Descrizione:

Cloruro di 2-(4-iodofenile)-3-(4-nitrofenile)-5-feniltetrazolio idrato, con il numero CAS 146-68-9, è un composto chimico che appartiene alla classe dei sali di tetrazolio. È caratterizzato dalla sua struttura complessa, che include un anello di tetrazolio e vari sostituenti aromatici, specificamente un gruppo 4-iodofenile e un gruppo 4-nitrofenile. Questo composto è tipicamente incontrato come un idrato, indicando la presenza di molecole d'acqua nella sua forma cristallina. È noto per la sua applicazione in saggi biochimici, in particolare negli studi di vitalità cellulare e proliferazione, dove funge da indicatore colorimetrico. La presenza dei sostituenti nitro e iodo contribuisce alle sue uniche proprietà elettroniche, influenzando la sua reattività e solubilità. Inoltre, il composto può presentare caratteristiche spettrali specifiche, rendendolo utile in chimica analitica. Devono essere adottate precauzioni di sicurezza quando si maneggia questa sostanza, poiché può comportare rischi per la salute a causa della sua natura chimica.

Formula: C₁₉H₁₃ClIN₅O₂

InChI: InChI=1/C19H14IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H,(H,21,22);1H

InChI key: InChIKey=JORABGDXCIBAFL-UHFFFAOYSA-M

SMILES: N(=O)(=O)C1=CC=C([N+]=2N(N=C(N2)C3=CC=CC=C3)C4=CC=C(I)C=C4)C=C1.[Cl-]

Sinonimi:

• 1-iodo-1-nitro-1H-tetrazol-1-ium chloride
• 2-(4-Iodophenyl)-3-(4-Nitrophenyl)-5-Phenyltetrazolium Chloride
• 2-(4-Iodophenyl)-3-(4-Nitrophrnyl)-5-Phenyl-2H-Tetrazoliu Chloride
• 2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride
• 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2,3-dihydro-1H-tetrazole hydrochloride (1:1)
• 2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride
• 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride
• 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride (1:1)
• 2H-Tetrazolium, 2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyl-, chloride
• 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium
• 3-(4-iodophenyl)-2-(4-nitrophenyl)-5-phenyl-2H-tetrazol-3-ium chloride
• 3-(P-Iodophenyl)-2-(P-Nitrophenyl)-5-Phenyl Tetrazolium Chloride
• 3-(p-Nitrophenyl)-2-(p-iodophenyl)-5-phenyltetrazolium chloride
• 4-Iodonitrotetrazolium Violet
• INT
• Int Chloride
• Iodonitro tetrazolium
• Iodonitrotetrazolium
• Iodonitrotetrazolium Chloride
• Iodonitrotetrazolium purple
• Iodonitrotetrazolium violet
• NSC 27620
• [2-(p-Iodophenyl)-3-(p-nitrophenyl)-5-phenyl-2H-tetrazolium chloride]
• p-Iodonitrotetrazolium violet
• INT, Iodonitrotetrazolium violet
• INT~2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride hydrate
• 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2h-tetrazoliuchloride
• IntA.R.
• 2(4-IODOPHENYL)-3(4-NITROPHENYL)-5-PHENYL-2H-Tetrazolium Chloride (INT)extrapure AR

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride [for Biochemical Research]

CAS: 146-68-9

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: >98.0%(HPLC)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 505.70

Ref: 3B-I0781

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium Chloride

CAS: 146-68-9

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 505.70

Ref: 3B-I0067

Iodonitrotetrazolium violet, 95%

CAS: 146-68-9

Used for dehydrogenase determination This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: 95%

Colore e forma: Powder, Cream to yellow

Peso molecolare: 505.70

Ref: 02-B22301

Iodonitrotetrazolium chloride

CAS: 146-68-9

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 505.6963

Ref: IN-DA003R0U

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride

CAS: 146-68-9

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: ≥ 98.0%

Colore e forma: Light-yellow to yellow powder

Peso molecolare: 505.70

Ref: 7W-GC3113

Iodonitrotetrazolium chloride

CAS: 146-68-9

Iodonitrotetrazolium chloride

Formula: C₁₉H₁₃IN₅O₂·Cl

Purezza: By hplc: 99.6% by area (Typical Value in Batch COA)

Colore e forma: almost white powder

Peso molecolare: 505.69629g/mol

Ref: 54-BII7020

INT

CAS: 146-68-9

INT

Purezza: ≥98%

Peso molecolare: 505.7g/mol

Ref: 54-BUP18178

INT

CAS: 146-68-9

Iodonitrotetrazolium chloride (INT), serves as the electron acceptor in a range of dehydrogenase colorimetric analyses.

Formula: C₁₉H₁₃ClIN₅O₂

Purezza: 98.46% - 99.43%

Colore e forma: Slightly Yellow Powder

Peso molecolare: 505.7

Ref: TM-T19374

Iodonitrotetrazolium Chloride (Technical Grade)

CAS: 146-68-9

Formula: C₁₉H₁₃IN₅O₂•(Cl)

Colore e forma: Neat

Ref: TR-I715613

Iodonitrotetrazolium chloride

CAS: 146-68-9

The monotetrazolium salt  Iodonitrotetrazolium chloride (INT), first described by Atkinson et al. (1950), is an iodinated derivative of TTC (2,3,5-Triphenyltetrazolium chloride) with an absorption λmax of 248 nm. The color produced by reduction of this iodonitro compound is a red to purple or brownish formazan with an absorption maximum at 485 to 492 nm (depending on the solvent). INT is often used to visualize dehydrogenase activity histochemically as well as in Western blot staining and as a staining agent for agar colony formation assays.  NAD or NADP-dependent dehydrogenases activity assays: NAD+- or NADP+-dependent dehydrogenase transfers electrons from a substrate (the electron donor, e.g. succinate) to NAD+ or NADP+, forming NADH and NADPH, respectively. Then, the final transfer of hydrogen to the tetrazolium salt is catalyzed by NADH or NADPH dehydrogenases (e.g. succinate dehydrogenase), leading to the reduction of INT and formation of the water-insoluble INT-formazan. 1 mol of formazan is produced for each mole of succinate utilized in the presence of INT. It is important to mention for applications in histology, that INT-formazan precipitates at the site of this latter dehydrogenase but not at the site of the original NAD+- or NADP+-dependent dehydrogenase activity.

Formula: C₁₉H₁₃ClIN₅O₂

Peso molecolare: 505.7 g/mol

Ref: 3D-I-7630

2(4-Iodophenyl)-3 (4-Nitrophenyl)-5-Phenyl-2H-Tetrazolium Chloride (INT) extrapure AR, 98%

CAS: 146-68-9

Formula: C₁₉H₁₃N₅O₂lCI

Purezza: min. 98%

Colore e forma: White to Dark Yellow to Dark Orange, Crystalline powder

Peso molecolare: 505.70

Ref: SR-40686