CAS 1463-10-1

5-Metiluridina

Descrizione:

5-Metiluridina, noto anche come ribotimidina, è un nucleoside che consiste nella base pirimidinica uracile con un gruppo metile attaccato alla posizione 5 dell'anello di uracile. Questa modifica migliora la stabilità e la funzionalità delle molecole di RNA, in particolare nel contesto del tRNA, dove svolge un ruolo nel corretto ripiegamento e nella funzione della molecola. La formula chimica di 5-Metiluridina è C10H13N2O5, ed è caratterizzata dalla sua capacità di partecipare a legami idrogeno grazie alla presenza di gruppi idrossile e amminici. Questo composto è solubile in acqua e presenta un punto di fusione relativamente basso. 5-Metiluridina è di interesse nella ricerca biochimica e ha potenziali applicazioni nei campi della biologia molecolare e della farmacologia, in particolare nello studio delle modifiche dell'RNA e dei loro effetti sull'espressione genica e sulla sintesi proteica. Il suo numero CAS, 1463-10-1, è utilizzato per l'identificazione in banche dati chimiche e contesti normativi.

Formula: C₁₀H₁₄N₂O₆

InChI: InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1

InChI key: InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Sinonimi:

• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosylthymine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Me-U
• 5-Methyl-Uridine
• 5-methyl-1-(beta-L-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-[(2xi)-beta-D-threo-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Ribosylthymine
• Ribothymidine
• Thymine riboside
• Uridine, 5-methyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1
• 5-Methyluridine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-ribofuranosyl-
• 5-methyuridine
• BETA-RIBOFURANOSIDE
• ribosylthymine/5-methyluridine
• 1-(BETA-D-RIBOFURANOSYL)THYMINE
• 1-β-D-Ribofuranosylthymine
• 5-methyluridine/ribothymidine
• 5-METHYL-D-URIDINE
• 5-Methyluridine (Patent )
• 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Methyluridine
• 5-methyl-uridin
• THYMINERIBOSIDE
• BETA-D-THYMINE RIBOSIDE
• 1-(BETA-D-RIBOFURANOSYL)THYMIDINE

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 258.23

Ref: 3B-M1405

5-Methyluridine, 99%

CAS: 1463-10-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₄N₂O₆

Purezza: 99%

Peso molecolare: 258.23

Ref: 02-H64259

Uridine, 5-methyl-

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 258.2280

Ref: IN-DA001DVT

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Purezza: ≥98%

Peso molecolare: 258.23g/mol

Ref: 54-BUP18363

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Peso molecolare: 258.23

Ref: 7W-GE5148

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Formula: C₁₀H₁₄N₂O₆

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 258.23g/mol

Ref: 54-OR52639

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine, a methylated nucleoside in human fluids, is higher in tumor patients; targeted by hypomethylating drugs in cancer therapy.

Formula: C₁₀H₁₄N₂O₆

Purezza: 99.72%

Colore e forma: Solid

Peso molecolare: 258.23

Ref: TM-T5282

5-Methyluridine

CAS: 1463-10-1

Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),

Formula: C₁₀H₁₄N₂O₆

Colore e forma: Neat

Peso molecolare: 258.23

Ref: TR-M338190

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.

Formula: C₁₀H₁₄N₂O₆

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 258.23 g/mol

Ref: 3D-NM04922

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purezza: 95%

Colore e forma: Solid, White to almost white crystal powder

Peso molecolare: 258.23

Ref: 10-F212233

5-Methyluridine extrapure, 98%

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Purezza: min. 98%

Colore e forma: White to off - white, Crystalline powder, Clear, Colourless

Peso molecolare: 258.23

Ref: SR-77337

5-Methyluridine

CAS: 1463-10-1

Formula: C₁₀H₁₄N₂O₆

Peso molecolare: 258.23

Ref: ST-EA-CP-Z6011