CAS 146368-11-8

1-{6-[(2,5-diossopirrolidin-1-il)ossi]-6-ossoesil}-2-[(1E,3E,5E)-5-(1-{6-[(2,5-diossopirrolidin-1-il)ossi]-6-ossoesil}-3,3-dimetil-5-sulfo-1,3-diidro-2H-indol-2-ilidene)penta-1,3-dien-1-il]-3,3-dimetil-3H-indolio-5-sulfonato

Descrizione:

La sostanza chimica nota come 1-{6-[(2,5-diossopirrolidin-1-il)ossi]-6-ossoesil}-2-[(1E,3E,5E)-5-(1-{6-[(2,5-diossopirrolidin-1-il)ossi]-6-ossoesil}-3,3-dimetil-5-sulfo-1,3-diidro-2H-indol-2-ilidene)penta-1,3-dien-1-il]-3,3-dimetil-3H-indolio-5-sulfonato, con numero CAS 146368-11-8, è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come sulfonato, indolo e moieties di pirrolidina. Questo composto presenta proprietà tipiche dei derivati dell'indolo, inclusa una potenziale attività biologica, che può essere attribuita alla sua capacità di interagire con vari bersagli biologici. La presenza di gruppi sulfonato suggerisce una maggiore solubilità in ambienti acquosi, migliorando le sue potenziali applicazioni in contesti biochimici. Inoltre, le unità di dioxopirrolidina possono contribuire alla sua stabilità e reattività. In generale, questa sostanza è probabilmente di interesse nella chimica medicinale e nello sviluppo di farmaci, in particolare per le sue potenziali applicazioni terapeutiche.

Formula: C₄₅H₅₂N₄O₁₄S₂

InChI: InChI=1/C45H52N4O14S2/c1-44(2)32-28-30(64(56,57)58)18-20-34(32)46(26-12-6-10-16-42(54)62-48-38(50)22-23-39(48)51)36(44)14-8-5-9-15-37-45(3,4)33-29-31(65(59,60)61)19-21-35(33)47(37)27-13-7-11-17-43(55)63-49-40(52)24-25-41(49)53/h5,8-9,14-15,18-21,28-29H,6-7,10-13,16-17,22-27H2,1-4H3,(H-,56,57,58,59,60,61)

SMILES: CC1(C)c2cc(ccc2N(CCCCCC(=O)ON2C(=O)CCC2=O)C1=CC=CC=CC1=[N+](CCCCCC(=O)ON2C(=O)CCC2=O)c2ccc(cc2C1(C)C)S(=O)(=O)[O-])S(=O)(=O)O

Sinonimi:

• Cy5
• Cy 5
• 2-((1E,3E,5Z)-5-(1-(5-Carboxypentyl)-3,3-dimethyl-5-(sulfinooxy)indolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
• 2-(5-(1-(5-Carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
• Sulfo-Cy5-acid
• Cy5-COOH
• Cy 5 acid

Sulfo-cyanine 5 Carboxylic Acid

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Purezza: >85.0%(T)(HPLC)

Colore e forma: Blue to Dark blue powder to crystal

Peso molecolare: 656.81

Ref: 3B-U0172

3H-Indolium, 2-[5-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-, inner salt

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 656.8093

Ref: IN-DA001DY3

CY5

CAS: 146368-11-8

CY5

Purezza: ≥95%

Peso molecolare: 656.81g/mol

Ref: 54-BUP04032

2-(5-(1-(5-Carboxypentyl)-3,3-Dimethyl-5-Sulfoindolin-2-Ylidene)Penta-1,3-Dien-1-Yl)-1-Ethyl-3,3-Dimethyl-3H-Indol-1-Ium-5-Sulfonate

CAS: 146368-11-8

2-(5-(1-(5-Carboxypentyl)-3,3-Dimethyl-5-Sulfoindolin-2-Ylidene)Penta-1,3-Dien-1-Yl)-1-Ethyl-3,3-Dimethyl-3H-Indol-1-Ium-5-Sulfonate

Purezza: 97%

Peso molecolare: 656.81g/mol

Ref: 54-OR1023902

CY5

CAS: 146368-11-8

Cy5 (Sulfo-Cyanine5) is a phalloidin dye used to label amino groups in peptides, proteins and oligonucleotides.

Formula: C₃₃H₄₀N₂O₈S₂

Purezza: 97.18% - 99.86%

Colore e forma: Solid

Peso molecolare: 656.81

Ref: TM-T15025

Cyanine dye 5

CAS: 146368-11-8

Cyanine dye 5 is a disulfide-linked dye that has been used as a fluorescence probe in the detection of reactive oxygen species. It has been shown to be reactive with mouse monoclonal antibodies and has been used as a model system for studying calcium binding and DNA duplexes. Cyanine dye 5 is also capable of detecting human serum, mitochondrial membrane potential, and clinical pathology.

Formula: C₃₃H₄₀N₂O₈S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 656.81 g/mol

Ref: 3D-FC75227

CY5

Prodotto controllato

CAS: 146368-11-8

Formula: C₃₃H₄₀N₂O₈S₂

Colore e forma: Neat

Peso molecolare: 656.809

Ref: TR-C951310

CY5 Triethylamine Salt

Prodotto controllato

CAS: 146368-11-8

Applications CY5 Triethylamine salt is the salt form of CY5(C951310) which is a photoswitchable cyanine dye. The photoswitching mechanism was investigated using thiol agents and it was concluded that photoconversion into the dark state is pH and thiol dependent and the dark state product is a cyanine-thiol adduct.
References Dempsey, G., et al.: J. Am. Chem. Soc., 131, 18192 (2009);

Formula: C₃₃H₄₀N₂O₈S₂·xC₆H₁₅N

Colore e forma: Neat

Peso molecolare: 656.81 + x(101.19)

Ref: TR-C951320

Didesulfo Bisbenzyl Cyanine 5 Monofunctional Hexanoic Acid Dye

Prodotto controllato

CAS: 146368-11-8

Formula: C₄₁H₄₅N₂O₂

Colore e forma: Neat

Peso molecolare: 597.808

Ref: TR-D359730

Cyanine dye 5 triethylamine salt

CAS: 146368-11-8

Cyanine dye 5 triethylamine salt is a fluorescent probe that can be used for the detection of cell nuclei and mitochondria. This compound has been shown to react with mouse monoclonal antibody in a subcutaneous tumor model system. It binds to calcium ions and is activated by reactive oxygen species. Cyanine dye 5 triethylamine salt has been shown to have high specificity in cancer tissues, but not in healthy tissues.

Formula: C₃₃H₄₀N₂O₈S₂•C₆H₁₅N

Purezza: Min. 95%

Peso molecolare: 758 g/mol

Ref: 3D-FC179941