CAS 147-24-0

Cloridrato di difenidramina

Descrizione:

Cloridrato di difenidramina è un antistaminico comunemente usato per alleviare i sintomi di allergia, febbre da fieno e raffreddore comune. È classificato come un antistaminico di prima generazione, il che significa che può attraversare la barriera ematoencefalica, portando spesso a effetti sedativi. La struttura chimica della difenidramina include un gruppo di difenilmetanolo, contribuendo alle sue proprietà farmacologiche. Agisce principalmente come un antagonista del recettore H1 dell'istamina, riducendo così gli effetti dell'istamina nel corpo. Oltre alle sue proprietà antistaminiche, la difenidramina è utilizzata anche come trattamento a breve termine per l'insonnia e come complemento nella gestione della cinetosi. La forma di sale cloridrato ne migliora la solubilità in acqua, rendendola adatta per varie formulazioni, tra cui compresse, capsule e preparazioni liquide. Gli effetti collaterali comuni possono includere sonnolenza, vertigini, bocca secca e visione offuscata. A causa delle sue proprietà sedative, si consiglia cautela nell'uso di macchinari o nella guida dopo il consumo.

Formula: C₁₇H₂₁NO·ClH

InChI: InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key: InChIKey=PCHPORCSPXIHLZ-UHFFFAOYSA-N

SMILES: C(OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2.Cl

Sinonimi:

• 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride
• 2-(diphenylmethoxy)-N,N-dimethylethanamine
• 2-(diphenylmethoxy)-N,N-dimethylethanamine hydrochloride (1:1)
• 2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride
• Alledryl
• Allergan
• Allergina
• Allergival
• Amidryl
• Asdrin
• Bagodryl
• Bax
• Bena
• Bena-Fedrin
• Benadril hydrochloride
• Benadryl
• Benison
• Benocten
• Benodine
• Benylin
• Benzantin
• Benzhydramine
• Benzhydramine hydrochloride
• Benzhydrol β-dimethylaminoethyl ether hydrochloride
• Denydryl
• Dibondrin
• Difenhidramina, Clorhidrato
• Difenhydramine hydrochloride
• Dimedrol
• Dimedrol hydrochloride
• Dimedrolum
• Diphantine
• Diphenhydramine HCl
• Diphenhydramine hydrochlorids
• Diphenhydramine, Chlorhydrate
• Diphenhydraminhydrochlorid
• Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
• Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride (1:1)
• Ethylamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride
• Fenylhist
• Halbmond
• Histacyl
• N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
• Noctomin
• Psilo-Balsam
• Resmin
• Restamin
• S 8
• Sedopretten
• Sekundal D
• Syntedril
• Theraflu
• Vena
• Wehydryl
• [2-(Diphenylmethoxy)ethyl]dimethylamine hydrochloride

Diphenhydramine Hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₁NOHCl

Peso molecolare: 255.4 : 36.46

Ref: ST-EA-CP-D23009

Diphenhydramine Hydrochloride

CAS: 147-24-0

Stability Hygroscopic
Applications Diphenhydramine is an H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic.
References Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),

Formula: C₁₇H₂₁NO·ClH

Colore e forma: Neat

Peso molecolare: 291.82

Ref: TR-D486900

[2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride

CAS: 147-24-0

Formula: C₁₇H₂₂ClNO

Purezza: 98%

Peso molecolare: 291.82

Ref: 10-F358131

Diphenhydramine Hydrochloride (1.0 mg/mL in Methanol)

CAS: 147-24-0

Formula: C₁₇H₂₁NO·ClH

Ref: TR-KIT1205-1ML

Diphenhydramine Hydrochloride (1.0 mg/mL in Methanol)

Prodotto controllato

CAS: 147-24-0

Formula: C₁₇H₂₁NO·ClH

Colore e forma: Single Solution

Peso molecolare: 291.82

Ref: TR-KIT1205

Diphenhydramine hydrochloride

Prodotto controllato

CAS: 147-24-0

Diphenhydramine is a first-generation antihistamine that crosses the blood-brain barrier and blocks the histamine H1 receptor. It has been used in the treatment of allergic reactions and bowel disease. The drug has shown no significant adverse effects in humans at doses up to 100 mg/day. Diphenhydramine is also used as an antiemetic, for motion sickness, and for other indications. It is available over the counter and by prescription. Side effects include dry mouth, blurred vision, constipation, difficulty urinating, and sleepiness. Diphenhydramine may interact with other drugs such as fructus (fruit) of Elaeagnus angustifolia (Russian olive), which can cause a decrease in blood pressure when taken together with diphenhydramine.

Formula: C₁₇H₂₁NO•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 291.82 g/mol

Ref: 3D-FD01515