CAS 147081-49-0

(R)-tert-butile 3-aminopirrolidina-1-carbossilato

Descrizione:

(R)-tert-butile 3-aminopirrolidina-1-carbossilato è un composto chirale caratterizzato dalla sua struttura ad anello di pirrolidina, che è un eterociclo a cinque membri contenente azoto. La presenza del gruppo tert-butile aumenta la sua lipofilia, rendendolo più solubile nei solventi organici. Questo composto presenta un gruppo amminico e un gruppo funzionale carbossilato, che contribuiscono al suo potenziale come blocco di costruzione nella sintesi organica e nelle applicazioni farmaceutiche. La chiralità della molecola, indicata dalla configurazione (R), è significativa nel determinare la sua attività biologica e le interazioni con altre molecole chirali. Il numero CAS 147081-49-0 identifica in modo univoco questa sostanza nei database chimici, facilitando il suo studio e la sua applicazione in vari campi, inclusa la chimica medicinale e lo sviluppo di farmaci. Le sue caratteristiche strutturali suggeriscono usi potenziali nella sintesi di molecole più complesse, in particolare nello sviluppo di farmaci mirati a specifici percorsi biologici. In generale, (R)-tert-butile 3-aminopirrolidina-1-carbossilato è un composto versatile con importanti implicazioni nella ricerca e applicazione chimica.

Formula: C₉H₁₈N₂O₂

InChI: InChI=1/C9H18N2O2.ClH/c1-9(2,3)13-8(12)11-5-4-7(10)6-11;/h7H,4-6,10H2,1-3H3;1H/t7-;/m1./s1

InChI key: InChIKey=CMIBWIAICVBURI-SSDOTTSWSA-N

SMILES: C(OC(C)(C)C)(=O)N1CC[C@@H](N)C1

Sinonimi:

• (+)-3-Aminopyrrolidine-1-carboxylic acid (R)-tert-butyl ester
• (3R)-(+)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine
• (3R)-3-Aminopyrrolidine-1-carboxylic acid tert-butyl ester
• (R)-(+)-3-Amino-1-(tert-butoxycarbonyl)pyrrolidine
• (R)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine
• (R)-1-Boc-3-aminopyrrolidine
• (R)-1-N-Boc-3-Aminopyrrolidine
• (R)-3-Amino-1-Boc-pyrrolidine
• (R)-3-Amino-1-tert-butoxycarbonylpyrrolidine
• (R)-3-Amino-N-(tert-butoxycarbonyl)pyrrolidine
• (R)-3-Aminopyrrolidine-1-carboxylic acid tert-butyl ester
• (R)-N-tert-Butoxycarbonyl-3-aminopyrrolidine
• (R)-tert-Butyl 3-aminopyrrolidine-1-carboxylate
• 1,1-Dimethylethyl (3R)-3-amino-1-pyrrolidinecarboxylate
• 1,1-dimethylethyl (3R)-3-aminopyrrolidine-1-carboxylate
• 1-Boc-(R)-3-aminopyrrolidine
• 1-Boc-3-(R)-aminopyrrolidine
• 1-N-Boc-3-(R)-aminopyrrolidine
• 1-Pyrrolidinecarboxylic acid, 3-amino-, 1,1-dimethylethyl ester, (3R)-
• 1-Pyrrolidinecarboxylic acid, 3-amino-, 1,1-dimethylethyl ester, (R)-
• 1-t-butoxycarbonyl-3-R-aminopyrrolidine
• N-Boc-(3R)-aminopyrrolidine
• R-1-N-Boc-3-Amino Pyrrolidine
• R-N-boc-3-Amino Pyrrolidine
• tert-Butyl (R)-3-amino-1-pyrrolidinecarboxylate
• tert-Butyl (R)-3-aminopyrrolidine-1-carboxylate
• tert-butyl (3R)-3-aminopyrrolidine-1-carboxylate
• (R)-N-Boc-3-aminopyrrolidine
• (R)-3-AMINO-1-N-(T-BUTOXYCARBONYL)PYRROLIDINE
• (R)-3-AMINO-1-N-BOC-PYRROLIDINE, CITRIC ACID SALT
• (R)-3-AMINO-1-N-(TERT-BUTOXYCARBONYL)PYRROLIDINE
• (R)-3-AMINO-N-BOC-PYRROLIDINE
• (R)-(+)-1-TBOC-3-AMINOPYRROLIDINE
• (3R)-3-Amino-1-(tert-butoxycarbonyl)pyrrolidine
• 3-AMINO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, (R)
• (R)-3-AMINO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(3R)-(+)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine

CAS: 147081-49-0

Formula: C₉H₁₈N₂O₂

Purezza: >98.0%(GC)(T)

Colore e forma: Colorless to Light orange to Yellow clear liquid

Peso molecolare: 186.26

Ref: 3B-B2920

(R)-(+)-1-Boc-3-aminopyrrolidine, 97%

CAS: 147081-49-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₈N₂O₂

Purezza: 97%

Colore e forma: Clear colorless to pale yellow, Liquid

Peso molecolare: 186.26

Ref: 02-H28188

(3R)-3-amino-1-(tert-butoxycarbonyl)-pyrrolidine

CAS: 147081-49-0

Formula: C₉H₁₈N₂O₂

Purezza: 97%

Colore e forma: Liquid

Peso molecolare: 186.2514

Ref: IN-DA0032DY

(3R)-3-Aminopyrrolidine, N1-BOC protected

CAS: 147081-49-0

(3R)-3-Aminopyrrolidine, N1-BOC protected

Formula: C₉H₁₈N₂O₂

Purezza: 95%

Colore e forma: colourless liquid

Peso molecolare: 186.25g/mol

Ref: 54-OR4635

(R)-3-Amino-1-N-Boc-pyrrolidine

CAS: 147081-49-0

Formula: C₉H₁₈N₂O₂

Purezza: 98.0%

Colore e forma: Liquid, Oil

Peso molecolare: 186.255

Ref: 10-F011315

(R)-1-Boc-3-Aminopyrrolidine

CAS: 147081-49-0

(R)-1-Boc-3-Aminopyrrolidine is a small molecule that inhibits 3-kinase. It has been shown to bind to the ATP binding site of PI3Kδ and inhibit its activity. This results in the inhibition of phosphoinositide production, which leads to decreased cell proliferation and survival. (R)-1-Boc-3-Aminopyrrolidine has also been shown to have selectivity for isoform α over β, γ, and δ. The drug binds specifically to the ATP binding site on PI3Kδ, but does not disrupt other interactions such as hydrogen bonding or pi stacking interactions with residues in the vicinity of the ATP binding site. The IC50 values for (R)-1-Boc-3-Aminopyrrolidine were determined using siRNA knockdown experiments against human isoform α PI3Kδ.

Formula: C₉H₁₈N₂O₂

Purezza: Min. 95%

Peso molecolare: 186.25 g/mol

Ref: 3D-FB41617