CAS 147118-36-3

N-[4-(4-Fluorofenil)-5-(idrossimetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetansulfonamide

Descrizione:

N-[4-(4-Fluorofenil)-5-(idrossimetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetansulfonamide, con numero CAS 147118-36-3, è un composto chimico che appartiene alla classe delle sulfonammidi. Questa sostanza presenta un anello di pirimidina sostituito con vari gruppi funzionali, tra cui un gruppo fluorofenile e un gruppo idrossimetile, che contribuiscono alla sua attività biologica. La presenza del gruppo metansulfonamida indica potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci. La struttura del composto suggerisce che potrebbe mostrare proprietà come l'inibizione degli enzimi o la modulazione delle vie biologiche, rendendolo di interesse nella scoperta di farmaci. Inoltre, l'atomo di fluoro può migliorare la lipofilia e la stabilità metabolica, che sono caratteristiche desiderabili nel design dei farmaci. In generale, le caratteristiche strutturali uniche e i gruppi funzionali di questo composto lo posizionano come un candidato per ulteriori indagini in applicazioni terapeutiche, in particolare in aree relative all'oncologia o alle malattie infettive.

Formula: C₁₆H₂₀FN₃O₃S

InChI: InChI=1S/C16H20FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-8,10,21H,9H2,1-4H3

InChI key: InChIKey=MSDYDUNHTAYBHV-UHFFFAOYSA-N

SMILES: C(O)C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinonimi:

• (Methanol) 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Mehyl-N-Mehylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino) Pyrimidin-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Me
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidin-5-Yl-Methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2- [(N-methyl-N- methylsulfony)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methonol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[N(N-methylsuophonyl)amino]pyrimidine-5-yl-methanol
• 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine
• 6-(E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-methylsulfonyl-methyl pyrimidine-5-yl)vinyl)(4R,6S)-2,2-dimethyl)(1,3)-dioxane
• Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate
• N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-6-isopropyl-5-(hydroxymethyl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• Rosuvastatin calcium intermediate R-1-2
• Z-7
• Z7
• Zd-2
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate(Z-7)
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n- methylsulfonyl)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino] pyrimidine-5-yl-methanol

Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-

CAS: 147118-36-3

Formula: C₁₆H₂₀FN₃O₃S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 353.4117

Ref: IN-DA001EN2

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

CAS: 147118-36-3

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

Purezza: 98%

Peso molecolare: 353.41g/mol

Ref: 54-PC105229

Rosuvastatin Impurity 40

CAS: 147118-36-3

Formula: C₁₆H₂₀FN₃O₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 353.41

Ref: 4Z-R-0944

4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol

Prodotto controllato

CAS: 147118-36-3

Formula: C₁₆H₂₀FN₃O₃S

Colore e forma: Neat

Peso molecolare: 353.41

Ref: 86-MM0936.02

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide

Prodotto controllato

CAS: 147118-36-3

Applications A Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Formula: C₁₆H₂₀FN₃O₃S

Colore e forma: Neat

Peso molecolare: 353.41

Ref: TR-F595380

4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol

CAS: 147118-36-3

Formula: C₁₆H₂₀FN₃O₃S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 353.41

Ref: 10-F093168

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6

Prodotto controllato

CAS: 147118-36-3

Applications N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6 is an isotope labelled Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Formula: C₁₆H₁₄D₆FN₃O₃S

Colore e forma: Neat

Peso molecolare: 359.45

Ref: TR-F595382

N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-Nmethylmethanesulfonamide

CAS: 147118-36-3

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Formula: C₁₆H₂₀FN₃O₃S

Purezza: Min. 95%

Peso molecolare: 353.41 g/mol

Ref: 3D-FF57578

Rosuvastatin Hydroxymethyl Impurity

CAS: 147118-36-3

Formula: C₁₆H₂₀FN₃O₃S

Peso molecolare: 353.41

Ref: ST-EA-CP-R1054