CAS 147366-41-4

Cloruro di 1-etil-2-[[3-etil-5-(3-metil-2(3H)-benzotiazolilidene)-4-osso-2-tiazolidinilidene]metil]piridinio (1:1)

Descrizione:

Cloruro di 1-etil-2-[[3-etil-5-(3-metil-2(3H)-benzotiazolilidene)-4-osso-2-tiazolidinilidene]metil]piridinio (1:1), con numero CAS 147366-41-4, è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, che includono un anello di piridinio e moieties di tiazolidina. Questa sostanza presenta proprietà tipiche dei composti di ammonio quaternario, come la solubilità in solventi polari e una potenziale attività antimicrobica. La presenza del gruppo benzotiazolo suggerisce possibili applicazioni in ambito farmaceutico o come colorante, data la sua struttura coniugata che potrebbe mostrare fluorescenza. La forma di sale cloruro del composto indica che è probabile che sia stabile e solubile in ambienti acquosi. La sua struttura intricata potrebbe anche contribuire a specifiche attività biologiche, rendendola di interesse nella chimica medicinale. Tuttavia, sarebbero necessari studi dettagliati sulla sua tossicità, stabilità e reattività per comprendere appieno le sue potenziali applicazioni e il profilo di sicurezza. Come per molti composti organici sintetici, è necessario osservare le condizioni adeguate di manipolazione e stoccaggio per garantire la sicurezza e l'integrità.

Formula: C₂₁H₂₂ClN₃OS₂

InChI: InChI=1/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;

InChI key: InChIKey=VSKYOTRJSLYFHX-UHFFFAOYSA-M

SMILES: O=C1C(SC(=CC=2[N+](CC)=CC=CC2)N1CC)=C3N(C)C=4C(S3)=CC=CC4.[Cl-]

Sinonimi:

• 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]pyridinium chloride (1:1)
• 1-ethyl-2-{(Z)-[(5E)-3-ethyl-5-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-4-oxo-1,3-thiazolidin-2-ylidene]methyl}pyridinium chloride
• FJ-776(formerly)
• Fj 776
• Mkt-077
• Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride
• Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride (1:1)
• Sdz-Mkt-077
• 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride
• MKT077;MKT-077;FJ-776
• MKT-077 >=98% (HPLC), powder

Pyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride (1:1)

CAS: 147366-41-4

Formula: C₂₁H₂₂ClN₃OS₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 432.0019

Ref: IN-DA001EV0

1-Ethyl-2-((Z)-((Z)-3-Ethyl-5-(3-mEthylbenzo[d]Thiazol-2(3H)-Ylidene)-4-oxoThiazolidin-2-Ylidene)mEthyl)Pyridin-1-Ium Chloride

CAS: 147366-41-4

1-Ethyl-2-((Z)-((Z)-3-Ethyl-5-(3-mEthylbenzo[d]Thiazol-2(3H)-Ylidene)-4-oxoThiazolidin-2-Ylidene)mEthyl)Pyridin-1-Ium Chloride

Purezza: 95%

Peso molecolare: 432.00g/mol

Ref: 54-OR1009464

MKT-077

CAS: 147366-41-4

MKT-077

Purezza: ≥98%

Peso molecolare: 432g/mol

Ref: 54-BUP04189

MKT-077

CAS: 147366-41-4

Formula: C₂₁H₂₂N₃OS₂Cl

Purezza: (HPLC) ≥ 98.0%

Colore e forma: Orange-red crystalline powder or solid

Peso molecolare: 432.00

Ref: 7W-GK8369

MKT-077

CAS: 147366-41-4

MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.

Formula: C₂₁H₂₂ClN₃OS₂

Purezza: 98.2%

Colore e forma: Solid

Peso molecolare: 432

Ref: TM-T5152

1-Ethyl-2-((Z)-((Z)-3-ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)pyridin-1-ium chloride

CAS: 147366-41-4

Purezza: 95.0%

Peso molecolare: 432.0

Ref: 10-F544604

MKT-077

Prodotto controllato

CAS: 147366-41-4

Applications MKT-077 is used in the treatment of Alzheimer’s diseases and other tauopathie’s. Also, is a rhodacyanine derivative that selectively targets cancer cells and overcomes tamoxifen resistance
References Jinwal, U. K., et al.: Pharm. Nanotechnol., 2, 217, (2014); Koren, J., et al. : PLoS One, 7, 35566 (2012)

Formula: C₂₁H₂₂N₃OS₂·Ci

Colore e forma: Neat

Peso molecolare: 432.0

Ref: TR-M425135

MKT-077

CAS: 147366-41-4

MKT-077 is a rhodacyanine dye analogue, which is a compound derived from the class of compounds known as rhodacyanines. This particular analogue is synthesized for its biochemical properties, specifically targeting mitochondrial functions. The mode of action of MKT-077 involves the selective accumulation within the mitochondria of cancer cells, where it induces mitochondrial stress and disrupts mitochondrial membrane potential. This disruption leads to apoptotic cell death, making it a potential agent in cancer treatment research.

Formula: C₂₁H₂₂ClN₃OS₂

Purezza: Min. 95%

Peso molecolare: 432 g/mol

Ref: 3D-XFA36641