CAS 1486466-31-2

CLOBETASOL IMPURITY J CRS

CAS: 1486466-31-2

CLOBETASOL IMPURITY J CRS

Ref: 41-Y0000571

Clobetasol Propionate Related Compound A (9α-Fluoro-11β-hydroxy-16β-methyl 3-oxo-androsta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one])

CAS: 1486466-31-2

Compounds containing an unfused furan ring, whether or not hydrogenated, in the structure, nesoi

Formula: C₂₅H₃₀ClFO₄

Colore e forma: White Powder

Peso molecolare: 448.18167

Ref: 45-1138427

Clobetasol Propionate EP Impurity J (Clobetasol Propionate USP Related Compound A)

CAS: 1486466-31-2

Formula: C₂₅H₃₀ClFO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 448.96

Ref: 4Z-C-101015

(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione

CAS: 1486466-31-2

Colore e forma: Neat

Ref: 86-MM0769.09

9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one

CAS: 1486466-31-2

Impurity Clobetasol Propionate EP Impurity J
Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),

Formula: C₂₅H₃₀ClFO₄

Colore e forma: Neat

Peso molecolare: 448.95

Ref: TR-F591800

Clobetasol Propionate EP Impurity J

CAS: 1486466-31-2

Formula: C₂₅H₃₀ClFO₄

Peso molecolare: 448.96

Ref: ST-EA-CP-C81023

(17R)-4-Chloro-5-ethyl-9-fluoro-11b-hydroxy-16b-methylspiro[androsta-1,4-diene-17,2(3H)-furan]-3,3-dione

CAS: 1486466-31-2

Clobetasol propionate is an organic acid with a chemical structure that is stable in pharmaceutical preparations. It is used to treat inflammatory skin disorders such as psoriasis and atopic dermatitis. Clobetasol propionate is an impurity of clobetasol, which has been shown to be chemically stable in preparations. The clobetasol propionate compound has been found to be more potent than other topical corticosteroids for the treatment of plaque psoriasis and atopic dermatitis.

Formula: C₂₅H₃₀ClFO₄

Purezza: Min. 95%

Peso molecolare: 448.95 g/mol

Ref: 3D-FF103612