CAS 14875-96-8

eme

Descrizione:

eme è una molecola organica complessa che svolge un ruolo cruciale in vari processi biologici, principalmente come gruppo prostetico nelle emoproteine come l'emoglobina e la mioglobina. È composta da un ione di ferro contenuto all'interno di un anello di porfirina, che è una struttura ciclica formata da quattro subunità di pirrolo collegate da ponti di metina. Il ferro in eme può esistere in diversi stati di ossidazione, permettendogli di partecipare a reazioni redox e di legarsi all'ossigeno, al monossido di carbonio e ad altre piccole molecole. eme è essenziale per il trasporto e lo stoccaggio dell'ossigeno negli organismi viventi, così come per il trasferimento di elettroni nella respirazione cellulare. La sua struttura consente il legame reversibile dell'ossigeno, rendendolo vitale per il metabolismo aerobico. Inoltre, eme è coinvolto in varie reazioni enzimatiche, comprese quelle catalizzate dai citocromi, che sono importanti per il metabolismo dei farmaci e i processi di disintossicazione. Il numero CAS 14875-96-8 identifica specificamente eme, evidenziando la sua importanza nella biochimica e nella medicina.

Formula: C₃₄H₃₀FeN₄O₄·2H

InChI: InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13?,27-14?,28-15?,29-14-,30-15-,31-16-,32-16?;

InChI key: InChIKey=KABFMIBPWCXCRK-ADOXYXQCSA-L

SMILES: C(CC([O-])=O)C=1C=2[N-]3[Fe+2]45[N]6=C(C2)C(CCC([O-])=O)=C(C)C6=CC=7[N-]4C(C=C8[N]5=C(C=C3C1C)C(C=C)=C8C)=C(C=C)C7C.[H+]

Sinonimi:

• 1,3,5,8-Tetramethyl-2,4-divinylporphine-6,7-dipropionic acid ferrous complex
• 21H,23H-Porphine, ferrate(2-) deriv.
• 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, iron complex
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N²¹,N²²,N²³,N²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, dihydrogen, (SP-4-2)-
• Ferrate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, hydrogen (1:2), (SP-4-2)-
• Ferroheme
• Ferroprotoporphyrin IX
• Hem Fe
• Heme
• Heme b
• Hydrogen [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]ferrate (heme)
• Iron protoporphyrin
• Iron protoporphyrin IX
• Iron(II) protoporphyrin IX
• Nsc 267100
• Protoheme
• Protoheme IX
• Protoporphyrin IX, iron deriv.
• Protoporphyrin, iron complex
• Reduced hematin
• [3,8,13,17-Tetramethyl-7,12-divinyl-21H,23H-porphine-2,8-dipropanoato(4-)-N21,N22,N23,N24]ferrate(2-) de dihydrogene (SP-4-2)
• [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]iron

Heme

CAS: 14875-96-8

Formula: C₃₄H₃₀FeN₄O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 616.4873

Ref: IN-DA00AOIN

Ferroheme

CAS: 14875-96-8

Ferroheme

Purezza: ≥95%

Peso molecolare: 616.49g/mol

Ref: 54-BUP08076

Hematin (Fe(II) Protoporphyrin IX)

CAS: 14875-96-8

Formula: C₃₄H₃₂FeN₄O₄

Peso molecolare: 616.50

Ref: 4Z-H-042001

Ferroheme

CAS: 14875-96-8

Ferroheme: iron-containing porphyrin in hemoglobin and other hemeproteins; colors tissues.

Formula: C₃₄H₃₂FeN₄O₄

Purezza: 97.63%

Colore e forma: Solid

Peso molecolare: 616.49

Ref: TM-T8948

Ferroprotoporphyrin IX

CAS: 14875-96-8

Stability Light Sensitive
Applications Ferroprotoporphyrin IX is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism. It is also an iron containing cofactor that is involved with a wide range of cellular functions including oxygen transport.
References Labbe, R.F., et. al.: Clin. Chem., 45, 146 (1999); Yuan, X., et al.: Proc. Natl. Acad. Sci. USA 113, E5144 (2016);

Formula: C₃₄H₃₂FeN₄O₄₂

Colore e forma: Neat

Peso molecolare: 616.49

Ref: TR-F307610

HEME

CAS: 14875-96-8

Heme is an iron-containing, non-protein molecule that is essential for life. Heme has a variety of biochemical properties and is important in the regulation of vital biological processes such as oxygen transport and metabolism of nitrogenous compounds. Heme can be found in two forms: heme A and heme B. The former consists of the protein globin combined with ferrous ion, while the latter is formed by the combination of protoporphyrin IX with ferrous ion. The synthesis of heme occurs through a series of reactions that involve oxidation and reduction reactions. The protoheme synthesis pathway results in the production of erythrocruorin, which is then converted to hemes A or B depending on its position in the globin protein chain. In addition to being an important cofactor for enzymes such as cytochrome c oxidase (complex IV), heme also functions as a substrate for heme oxygenase, which removes it from circulation to produce biliver

Formula: C₃₄H₃₂FeN₄O₄

Purezza: Min. 95%

Peso molecolare: 616.5 g/mol

Ref: 3D-PAA87596