CAS 149-29-1

Patulina

Descrizione:

Patulina è una micotossina prodotta da varie specie di funghi, in particolare Penicillium e Aspergillus. È un solido cristallino incolore o giallo pallido con un odore caratteristico. Patulina è noto per le sue proprietà antimicrobiche, che possono inibire la crescita di alcuni batteri e funghi; tuttavia, è principalmente riconosciuto per i suoi potenziali rischi per la salute, in particolare nella sicurezza alimentare. Si trova comunemente in frutta in decomposizione, specialmente mele, e può contaminare succhi di frutta e altri prodotti alimentari. Patulina è classificato come sostanza pericolosa a causa dei suoi effetti tossici, che possono includere disturbi gastrointestinali e potenziale cancerogenicità. Le agenzie di regolamentazione hanno stabilito limiti per i livelli di Patulina nei prodotti alimentari per mitigare i rischi per la salute. La sua struttura chimica presenta un anello di lattone, contribuendo alla sua reattività e attività biologica. A causa della sua presenza nelle forniture alimentari, la ricerca in corso si concentra su metodi per la rilevazione, prevenzione e degradazione di Patulina nei prodotti agricoli.

Formula: C₇H₆O₄

InChI: InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

InChI key: InChIKey=ZRWPUFFVAOMMNM-UHFFFAOYSA-N

SMILES: OC1C=2C(OC(=O)C2)=CCO1

Sinonimi:

• 4,6-Dihydro-4-hydroxy-2H-furo[3,2-c]pyran-2-on
• 4,6-dihidro-4-hidroxi-2H-furo[3,2-c]piran-2-ona
• 4,6-dihydro-4-hydroxy-2H-furo[3,2-c]pyran-2-one
• 4,6-dihydro-4-hydroxy-2H-furo[3,2-c]pyranne-2-one
• 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
• <span class="text-smallcaps">DL</span>-Patulin
• Acetic acid, (2,4-dihydroxy-2H-pyran-3(6H)-ylidene)-, 3,4-lactone
• Clairformin
• Clavacin
• Clavatin
• Claviformin
• DL-Patulin
• Expansin
• Expansin (antibiotic)
• Expansine
• Gigantin
• Leucopin
• Mycoin
• Mycoin C
• Mycoin C3
• Mycoin C₃
• Nsc 32951
• Nsc 8120
• Patulin
• Patuline
• Penicidin
• Terinin
• CCRIS 4940
• Tercinin
• Claviform
• Mycoine C3
• HSDB 3522
• (2,4-Dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid, 3,4-lactone
• 2H-Pyran-delta(sup 3(6H),alpha)-acetic acid, 2,4-dihydroxy-, 3,4-lactone
• (4R)-4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
• 5-18-03-00005 (Beilstein Handbook Reference)
• 4H-Furo[3,2-c]pyran-2(6H)-one, 4-hydroxy-
• Penatin
• 4H-Furo(3,2-c)pyran-2(6H)-one, 4-hydroxy-
• BRN 0149675
• 2,4-Dihydroxy-2H-pyran-delta-3(6H),alpha-acetic acid-3,4-lactone
• (4S)-4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
• 4H-Furo(3,3-c)pyran-2(6H)-one, 4-hydroxy-
• (2,4-Dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid-3,4-lactone

4H-FURO[3,2-C]PYRAN-2(6H)-ONE, 4-HYDROXY-

CAS: 149-29-1

Formula: C₇H₆O₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 154.1201

Ref: IN-DA001LCB

Patulin Standard Solution

CAS: 149-29-1

Patulin Standard Solution

Formula: C₇H₆O₄

Colore e forma: Colourless Liquid

Peso molecolare: 154.12g/mol

Ref: 54-BIMS108

Patulin from Penicillium expansum

CAS: 149-29-1

Patulin from Penicillium expansum

Formula: C₇H₆O₄

Purezza: By hplc: 100% (Typical Value in Batch COA)

Colore e forma: white crystals

Peso molecolare: 154.12g/mol

Ref: 54-BIP1003

Patulin

CAS: 149-29-1

Formula: C₇H₆O₄

Purezza: ≥ 98.0%

Colore e forma: White to pale yellow crystalline powder

Peso molecolare: 154.12

Ref: 7W-GA7014

Patulin 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 149-29-1

Formula: C₇H₆O₄

Colore e forma: Single Solution

Peso molecolare: 154.12

Ref: 04-A15896000AL-100

Patulin 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 149-29-1

Formula: C₇H₆O₄

Colore e forma: Single Solution

Peso molecolare: 154.12

Ref: 04-V15896000AL-100

Patulin

Prodotto controllato

CAS: 149-29-1

Formula: C₇H₆O₄

Colore e forma: Neat

Peso molecolare: 154.12

Ref: 04-C15896000

PATULIN

CAS: 149-29-1

Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.

Formula: C₇H₆O₄

Purezza: 99.91% - 99.98%

Colore e forma: Compact Prisms Or Thick Plates From Ether Or Chloroform White Crystalline

Peso molecolare: 154.12

Ref: TM-T3936

Patulin

CAS: 149-29-1

Patulin is a mycotoxin, which is a toxic secondary metabolite produced by certain species of fungi, particularly those within the genera Penicillium, Aspergillus, and Byssochlamys. It is predominantly sourced from moldy fruits, especially apples and apple-derived products, where these fungi thrive and synthesize the compound. The mode of action of patulin involves disrupting cellular processes by forming covalent adducts with proteins and nucleic acids, ultimately leading to cellular damage and oxidative stress.

Formula: C₇H₆O₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 154.12 g/mol

Ref: 3D-FP31796

Patulin

CAS: 149-29-1

Formula: C₇H₆O₄

Peso molecolare: 154.12

Ref: ST-EA-CP-A174011

Patulin

CAS: 149-29-1

Stability Hygroscopic
Applications Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models. The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM. At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells. In 1944, this compound was tested in a clinical trial for potential antibiotic
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Scott, P., et al.: J. Agric. Food Chem., 20, 450 (1972), Aden, D., et al.: Nature, 282, 615 (1979), Surralles, J., et al.: Mutat. Res., 341, 169 (1995), Alves, I., et al.: Mutagenesis, 15, 229 (2000), Liu, B., et al.: Toxicol. Appl. Pharmacol., 191, 255 (2003), Puel, O., Galtier, P., and Oswald, I.P. Biosynthesis and toxicological effects of patulin. Toxins 2(4) 613-631 (2010). Liu, B., Wu, T., Yu, F., et al. Induction of oxidative stress response by the mycotoxin patulin in mammalian cells. Toxicol Sci 95(2) 340-347 (2007). Chalmers, I., and Clarke, M. Commentary: The 1994 patulin trial: The first properly controlled multicentre trial conducted under the aegis of the British Medical Research Council. Int J Epidemiol 32 253-260 (2004).

Formula: C₇H₆O₄

Colore e forma: Off-White To Yellow

Peso molecolare: 154.12

Ref: TR-P206500