CAS 149-64-4

Buscopan

Descrizione:

Buscopan, con il numero CAS 149-64-4, è il nome commerciale dell'ingrediente attivo butilbromuro di scopolamina, che è un farmaco antispasmodico. Viene utilizzato principalmente per alleviare il dolore addominale e il disagio causati da spasmi nel tratto gastrointestinale, così come in altri muscoli lisci. Il butilbromuro di scopolamina agisce bloccando l'azione dell'acetilcolina sui recettori muscarinici, portando al rilassamento muscolare. La sostanza viene generalmente somministrata per via orale o tramite iniezione ed è nota per il suo rapido inizio d'azione. In termini di caratteristiche fisiche, è una polvere cristallina bianca o bianco sporco solubile in acqua e alcol. Il composto è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere secchezza delle fauci, vertigini e visione offuscata a causa delle sue proprietà anticolinergiche. Come con qualsiasi farmaco, è importante utilizzare Buscopan sotto la guida di un professionista sanitario per garantire sicurezza ed efficacia.

Formula: C₂₁H₃₀NO₄·Br

InChI: InChI=1S/C21H30NO4.BrH/c1-3-4-10-22(2)17-11-15(12-18(22)20-19(17)26-20)25-21(24)16(13-23)14-8-6-5-7-9-14;/h5-9,15-20,23H,3-4,10-13H2,1-2H3;1H/q+1;/p-1/t15-,16-,17-,18+,19-,20+,22?;/m1./s1

InChI key: InChIKey=HOZOZZFCZRXYEK-GSWUYBTGSA-M

SMILES: C(CCC)[N+]1(C)[C@]2([C@@]3([C@@](O3)([C@@]1(C[C@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].[Br-]

Sinonimi:

• (1S,2R,4S,5S)-9-butyl-7-[(3-hydroxy-2-phenylpropanoyl)oxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• (1S,2R,4S,5S)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 8-butyl-6β,7β-epoxy-3α-hydroxy-, bromide, (-)-tropate
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, [7(S)-(1α,2β,4β,5α,7β)]-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1α,2β,4β,5α,7β)-
• Amisepan
• Buscapine
• Buscol
• Buscolamin
• Buscolysin
• Buscolysine
• Buscopan
• Butylmin
• Butylscopolamine bromide
• Butylscopolammonium bromide
• Donopon
• Hyoscine Butylobromide
• Hyoscine butobromide
• Hyoscine butyl bromide
• Hyoscine butylbromide
• Hyoscine-N-Butyl Bromide
• Hyoscinen butylbromide
• Joscine
• Monospan
• N-Butylhyoscine bromide
• N-Butylscopolamine bromide
• N-Butylscopolaminium bromide
• N-Butylscopolammonium bromide
• N-butylhyoscinium bromide
• Scobro
• Scobron
• Scobutil
• Scobutyl
• Scopolamine Butylbromide
• Scopolamine bromobutylate
• Scopolamine butobromide
• Scopolamine butyl bromide
• Scopolan
• Sparicon
• Sporamin
• Sporamin (pharmaceutical)
• Stibron
• Tirantil
• Tropic acid, (-)-, ester with 8-butyl-6β,7β-epoxy-3α-hydroxy-1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-tropanium bromide
• 1αH,5αH-Tropanium, 8-butyl-6β,7β-epoxy-3α-hydroxy-, bromide, (-)-tropate
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1α,2β,4β,5α,7β)-

Buscopan

CAS: 149-64-4

Formula: C₂₁H₃₀BrNO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 440.38

Ref: 3B-B6485

Hyoscine Butylbromide

CAS: 149-64-4

Colore e forma: Neat

Ref: 61-FOR0683.00

HYOSCINE BUTYLBROMIDE CRS

CAS: 149-64-4

HYOSCINE BUTYLBROMIDE CRS

Formula: C₂₁H₃₀BrNO₄

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 440.3712

Ref: 41-H1450000

HYOSCINE BUTYLBROMIDE FOR SYSTEM SUITABILITY CRS

CAS: 149-64-4

HYOSCINE BUTYLBROMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001983

Hyoscine butylbromide

CAS: 149-64-4

Hyoscine butylbromide

Formula: C₂₁H₃₀BrNO₄

Purezza: 99.7%

Colore e forma: White

Peso molecolare: 439.13582

Ref: 47-198

Scopolamine Butylbromide

CAS: 149-64-4

Formula: C₂₁H₃₀BrNO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 440.3712

Ref: IN-DA007HY8

Scopolamine butylbromide, EP grade

CAS: 149-64-4

Formula: C₂₁H₃₀BrNO₄

Purezza: ≤ 0.10% (HPLC)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 440.37

Ref: 7W-GP6962

Hyoscine Butylbromide (N-Butyl Scopolamine Bromide, N-Butyl Hyoscine Bromide)

CAS: 149-64-4

Formula: C₂₁H₃₀NO₄·Br

Colore e forma: White To Off-White Solid

Peso molecolare: 360.47 79.90

Ref: 4Z-S-013

Scopolamine butylbromide

CAS: 149-64-4

Formula: C₂₁H₃₀BrNO₄

Purezza: (Titration) 98.0 - 102.0 % (dried basis)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 440.37

Ref: 7W-GP9811

Hyoscine Butylbromide-d9 (N-Butyl Scopolamine Bromide-d9, N-Butyl Hyoscine Bromide-d9)

CAS: 149-64-4

Formula: C₂₁H₂₁D₉NO₄·Br

Colore e forma: White To Off-White Solid

Peso molecolare: 369.53 79.90

Ref: 4Z-S-0115

(-)-Scopolamine-N-butylbromide

CAS: 149-64-4

Colore e forma: Neat

Ref: LP-HYO-818-50

Hyoscine Butylbromide

CAS: 149-64-4

Colore e forma: Neat

Ref: 86-MM0683.00

Scopolamine butylbromide

CAS: 149-64-4

Formula: C₂₁H₃₀BrNO₄

Purezza: 95%~99%

Peso molecolare: 440.378

Ref: BP-BP1273

Scopolamine butylbromide

CAS: 149-64-4

Scopolamine butylbromide ((-)-Scopolamine butylbromide) is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).

Formula: C₂₁H₃₀NO₄·Br

Purezza: 99.02% - 99.95%

Colore e forma: White Powder

Peso molecolare: 440.37

Ref: TM-T2183

N-Butylscopolammonium Bromide-d9

Prodotto controllato

CAS: 149-64-4

Stability Hygroscopic
Applications N-Butylscopolammonium Bromide (B693752) acts as an anticholinergic and antispasmodic. This is the labeled analog.
References Lee, J.R., et al.: Clin. Radiol., 33, 273 (1982), Bauer, et al.: Arzneim.-Forsch., 18, 1132 (1986), Steger, A.C., et al.: Am. J. Gastroenterol., 81, 615 (1986),

Formula: C₂₁H₂₁D₉NO₄•Br

Colore e forma: Off-White

Peso molecolare: 369.52799

Ref: TR-B693752

N-Butylscopolammonium Bromide

CAS: 149-64-4

Formula: C₂₁H₃₀NO₄·Br

Colore e forma: White

Peso molecolare: 440.37

Ref: TR-B693750

(-)-Scopolamine N-butyl bromide

CAS: 149-64-4

(-)-Scopolamine N-butyl bromide is an anti-cholinergic drug that is used for the diagnosis and treatment of bowel diseases. It has been shown to be effective in two different animal models of bowel disease, one of which was induced by dextran sulfate sodium. (-)-Scopolamine N-butyl bromide has been shown to decrease motility and increase tone in the colon, as well as reduce the severity of diarrhea in animals with experimental colitis. It also has a sedative effect on the gastrointestinal tract that may be due to its ability to bind to acetylcholine receptors.

Formula: C₂₁H₃₀NO₄Br

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 440.37 g/mol

Ref: 3D-FS10191

N-Butyl Scopolamine Bromide

CAS: 149-64-4

Formula: C₂₁H₃₀NO₄Br

Peso molecolare: 360.48 : 79.90

Ref: ST-EA-CP-S114012