CAS 149231-65-2
:N-acetil-tir-val-ala-asp 7-amido-4-*metilcumarina
Descrizione:
N-acetil-tir-val-ala-asp 7-amido-4-metilcumarina, identificato dal suo numero CAS 149231-65-2, è un composto sintetico che appartiene alla classe dei derivati peptidici. Questa sostanza presenta una combinazione di amminoacidi, specificamente N-acetiltirosina, valina, alanina e acido aspartico, legati insieme in una sequenza specifica. La presenza del gruppo 7-amido-4-metilcumarina suggerisce che ha proprietà fluorescenti, rendendola utile in saggi biochimici e applicazioni di ricerca, in particolare nello studio dell'attività enzimatica o delle interazioni proteiche. Il gruppo N-acetile migliora la sua solubilità e stabilità, mentre il componente cumarina può fungere da gruppo reporter in varie tecniche analitiche. In generale, questo composto è caratterizzato dalla sua struttura peptidica, potenziale bioattività e utilità in applicazioni basate sulla fluorescenza, contribuendo alla sua rilevanza nella ricerca biochimica e farmaceutica.
Formula:C33H39N5O10
Sinonimi:- Ac-Yvad-Amc
Ordinare per
Purezza (%)
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100
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0
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50
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90
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95
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100
4 prodotti.
Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.Formula:C33H39N5O10Purezza:99.3%Colore e forma:White PowderPeso molecolare:665.7Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a peptide that is used as a research tool to activate ion channels in cells and study the effects of ligands on these channels. It is also used in cell biology to study protein interactions, although it does not bind to any specific receptor. Ac-Tyr-Val-Ala-Asp-AMC belongs to the group of inhibitors and can be used for pharmacological purposes. The chemical structure of this peptide consists of a covalent bond between an amino acid and an acetylated form of a fluorescent molecule, which makes it suitable for use in fluorescence microscopy. Acetylated Tyr (Ac-Tyr) is one of the six amino acids found in proteins and has the ability to inhibit the activity of ion channels by binding to their external cavity. Acetylation at position 2 or 3 on Tyr can increase its affinity for calcium ion channels and affect their activation or deFormula:C33H39N5O10Purezza:Min. 95%Peso molecolare:665.69 g/molAc-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a compound that has been shown to induce apoptotic cell death in MDA-MB-231 breast cancer cells. It inhibits the activity of proteases, which are enzymes that degrade proteins. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit serine proteases and granule neurons, which are proteins in the brain that regulate the production of atp levels. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit muscle cell proliferation. Acetylcholine (ACh) is a neurotransmitter responsible for signaling between nerve cells in the central nervous system and other parts of the body. Acetylcholine is synthesized by choline acetyltransferase (ChAT), an enzyme that breaks down acetylcholine into choline and acetate. Inhibition of ChAT leads to a decrease inFormula:C33H39N5O10Purezza:Min. 95%Peso molecolare:665.69 g/mol


