CAS 150322-43-3

Prasugrel

Descrizione:

Prasugrel è un farmaco antipiastrinico utilizzato principalmente per ridurre il rischio di eventi cardiovascolari in pazienti con sindrome coronarica acuta sottoposti a intervento coronarico percutaneo. È un derivato delle tienopiridine che agisce inibendo in modo irreversibile il recettore P2Y12 sulle piastrine, prevenendo così l'aggregazione piastrinica. Prasugrel è caratterizzato dalla sua rapida assorbimento e conversione in un metabolita attivo, il che ne migliora l'efficacia rispetto ad altri agenti antipiastrinici. La formula chimica di Prasugrel è C20H20FNO3S e ha un peso molecolare di circa 343,44 g/mol. La sostanza viene tipicamente somministrata in forma di pro-farmaco, richiedendo attivazione metabolica per esercitare i suoi effetti terapeutici. Prasugrel è noto per la sua farmacocinetica e farmacodinamica relativamente prevedibili, rendendolo una scelta preferita in determinati contesti clinici. Tuttavia, è associato a un aumento del rischio di sanguinamento, richiedendo una selezione e un monitoraggio attenti dei pazienti. Il suo profilo di sicurezza ed efficacia è stato stabilito attraverso vari studi clinici, contribuendo alla sua accettazione nella pratica clinica per la gestione di eventi cardiovascolari trombotici.

Formula: C₂₀H₂₀FNO₃S

InChI: InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3

InChI key: InChIKey=DTGLZDAWLRGWQN-UHFFFAOYSA-N

SMILES: C(C(=O)C1CC1)(N2CC3=C(CC2)SC(OC(C)=O)=C3)C4=C(F)C=CC=C4

Sinonimi:

• 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
• 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone
• 5-[2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl]-4,5,6,7-
• Acetic acid 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl ester
• Cs 747
• Effient free base
• Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-
• Ly 640315
• Prasugrel Base
• Prasugrel [INN]
• Tetrahydrothieno[3,2-C]Pyridin-2-Yl Acetate
• Thieno[3,2-c]pyridine, ethanone deriv.
• [5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxo-ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• Prasugrel
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-

Prasugrel

CAS: 150322-43-3

Formula: C₂₀H₂₀FNO₃S

Purezza: >98.0%(T)(HPLC)

Colore e forma: Light yellow to Yellow to Orange powder to crystal

Peso molecolare: 373.44

Ref: 3B-P2040

2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone

CAS: 150322-43-3

Formula: C₂₀H₂₀FNO₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 373.4411

Ref: IN-DA001MIM

Prasugrel

CAS: 150322-43-3

Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME;

Formula: C₂₀H₂₀FNO₃S

Purezza: 99.62% - 99.82%

Colore e forma: White Solid

Peso molecolare: 373.44

Ref: TM-T0230

Prasugrel

CAS: 150322-43-3

Formula: C₂₀H₂₀FNO₃S

Colore e forma: Off-White Solid

Peso molecolare: 373.44

Ref: 4Z-P-391

Prasugrel

CAS: 150322-43-3

Prasugrel

Purezza: 99%

Peso molecolare: 373.44g/mol

Ref: 54-PC109116

Prasugrel

CAS: 150322-43-3

Prasugrel

Purezza: ≥98%

Peso molecolare: 373.44g/mol

Ref: 54-BUP15051

Prasugrel

CAS: 150322-43-3

Formula: C₂₀H₂₀FNO₃S

Peso molecolare: 373.44

Ref: 7W-GP4257

(±)-Prasugrel-d3 (acetate-d3)

CAS: 1127253-02-4, 150322-43-3

Purezza: 99 atom % D

Colore e forma: Off White Solid

Peso molecolare: 376.46

Ref: 3U-D7536

Prasugrel

CAS: 150322-43-3

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 373.44000244140625

Ref: 10-F390330

Prasugrel - Bio-X ™

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties. 
Prasugrel is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₀H₂₀FNO₃S

Purezza: (%) Min. 95%

Peso molecolare: 373.44 g/mol

Ref: 3D-BP164290

Prasugrel

CAS: 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties.

Formula: C₂₀H₂₀FNO₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 373.44 g/mol

Ref: 3D-FP10815

Prasugrel

CAS: 150322-43-3

Applications Prasugrel is a platelet inhibitor that reduces aggregation of platelets by being a P2Y12(ADP receptor) inhibitor.

Formula: C₂₀H₂₀FNO₃S

Colore e forma: Neat

Peso molecolare: 373.44

Ref: TR-P701188