CAS 152460-10-1

6-Metil-N-[4-(piridin-3-il)pirimidin-2-il]benzene-1,3-diammina

Descrizione:

6-Metil-N-[4-(piridin-3-il)pirimidin-2-il]benzene-1,3-diammina, con il numero CAS 152460-10-1, è un composto chimico caratterizzato dalla sua struttura complessa, che include un anello benzenico sostituito da gruppi amminici e un gruppo metile, oltre a una porzione di pirimidina e piridina. Questo composto tipicamente mostra proprietà associate alle ammine aromatiche, come la potenziale solubilità in solventi organici e una polarità moderata. La presenza di eterocicli contenenti azoto come la piridina e la pirimidina può conferire proprietà elettroniche uniche, influenzando la sua reattività e potenziale attività biologica. Può anche partecipare a legami idrogeno grazie ai gruppi amminici, il che può influenzare le sue interazioni in vari ambienti chimici. Inoltre, composti di questa natura sono spesso studiati per le loro potenziali applicazioni in prodotti farmaceutici, agrochimici o come intermedi nella sintesi organica. Tuttavia, proprietà fisiche specifiche come il punto di fusione, il punto di ebollizione e la solubilità dovrebbero essere determinate sperimentalmente o ottenute da database affidabili per applicazioni precise.

Formula: C₁₆H₁₅N₅

InChI: InChI=1S/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21)

InChI key: InChIKey=QGAIPGVQJVGBIA-UHFFFAOYSA-N

SMILES: N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=C(C)C=CC(N)=C3

Sinonimi:

• 1,3-Benzenediamine 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-
• 1,3-Benzenediamine, 4-methyl-N³-[4-(3-pyridinyl)-2-pyrimidinyl]-
• 2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine
• 4-Methyl-3-[4-(3-pyridinyl)pyrimidin-2-ylamino]aniline
• 4-Methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
• 4-Methyl-N3-[4-(3-pyridinyl)-2-pyrimidin-yl]-1,3-benzenediamine
• 4-Methyl-N³-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine
• 4-Methyl-N³-[4-(pyridin-3-yl)pyrimidin-2-yl]-1,3-benzenediamine
• 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-Benzenediamine
• 4-methyl-N~3~-(4-pyridin-3-ylpyrimidin-2-yl)benzene-1,3-diamine
• 6-methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
• N-(2-Methyl-5-Amino Phenyl)-4-(3-Pyridyl)-2-Pyrimidine
• N-(2-Methyl-5-aminophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
• N-(2-methyl-5-aminophenyl)-4-(3-pyridyl)-2-pyrimidine amine
• N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
• N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)pyrimidin-2-amine
• N-(5-Amino-2-methylphenyl)-4-(pyridin-3-yl)pyrimidin-2-ylamine
• N-(5-Amino-2-methylphenyl)-6-(pyridin-3-yl)-2-pyrimidinamine
• N-(5-Amino-2-methylphenyl)-N-[4-(3-pyridyl)pyrimidin-2-yl]amine
• N-(5-Amino-2-methylphenyl)[4-(3-pyridyl)-2-pyrimidinyl]amine
• N-(5-amino-2-methylphenl)-4-(3-pyridyl)-2-pyrimidine-amine
• N-(5-amino-2-methylphenyl)-4-(3-pyrdyl)-2-pydimidineamine
• N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine

2-(5-Amino-2-methylanilino)-4-(3-pyridyl)pyrimidine

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Purezza: >98.0%(T)(HPLC)

Colore e forma: Light orange to Yellow to Green powder to crystal

Peso molecolare: 277.33

Ref: 3B-A2308

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 277.3238

Ref: IN-DA003440

6-Methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine

CAS: 152460-10-1

6-Methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine

Purezza: 98%

Peso molecolare: 277.32g/mol

Ref: 54-OR345028

Imatinib EP Impurity F

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Colore e forma: Yellow Solid

Peso molecolare: 277.33

Ref: 4Z-I-0913

Imatinib EP Impurity F

Prodotto controllato

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Colore e forma: Neat

Peso molecolare: 277.32

Ref: 86-MM3566.06

Imatinib EP Impurity F

CAS: 152460-10-1

Formula: C₁₆H₁₅N₅

Peso molecolare: 277.32

Ref: ST-EA-CP-I5006

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

Prodotto controllato

CAS: 152460-10-1

Impurity Imatinib EP Impurity F
Applications N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (Imatinib EP Impurity F) is a selective inhibitor of protein kinase C (PKC). It is a COVID19-related research product.
References Szczylik, C., et al.: Science, 253, 562 (1991), Geissler, J., et al.: Cancer Res., 52, 4492 (1992), Paul, R., et al.: J. Med. Chem., 36, 2716 (1993),

Formula: C₁₆H₁₅N₅

Colore e forma: Neat

Peso molecolare: 277.32

Ref: TR-A618220

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 277.33099365234375

Ref: 10-F080006

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Imatinib is an anticancer drug that belongs to the class of trimethyls. It is a potent inhibitor of tyrosine-specific protein kinases, including Bcr-Abl and Src family kinases. It has been shown to have antineoplastic properties in human cells in vitro. Imatinib is structurally similar to the anticancer agent lapatinib and inhibits G1 phase cell cycle progression by preventing phosphorylation of retinoblastoma protein (Rb). Imatinib is also genotoxic due to its structural similarity to other known genotoxic compounds such as bromo-2′-deoxyuridine and 2-chloroimidazole.

Formula: C₁₆H₁₅N₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 277.32 g/mol

Ref: 3D-FA15934

TLC9995-0188

CAS: 152460-10-1

Tyrosine-protein kinase ABL, IC50: 1500 nM

Formula: C₁₆H₁₅N₅

Colore e forma: Yellow Solid

Peso molecolare: 277.331

Ref: TM-T116837