CAS 152658-36-1

6S-Nalfurafine

Prodotto controllato

CAS: 152658-36-1

Applications 6S-Nalfurafine is a stereoisomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)

Formula: C₂₈H₃₂N₂O₅

Colore e forma: Neat

Peso molecolare: 476.56

Ref: TR-N255615

6S-Nalfurafine-d3

Prodotto controllato

CAS: 152658-36-1

Applications 6S-Nalfurafine-d3 is the labeled analogue of 6S-Nalfurafine (N255615), a stereoisomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)

Formula: C₂₈D₃H₂₉N₂O₅

Colore e forma: Neat

Peso molecolare: 479.583

Ref: TR-N255617

6S-Nalfurafine (1 mg/ml in Acetonitrile)

Prodotto controllato

CAS: 152658-36-1

Formula: C₂₈H₃₂N₂O₅

Colore e forma: Single Solution

Peso molecolare: 476.56

Ref: TR-KIT6355