CAS 152764-52-8

acido 4-[(1E)-1-[4-[2-(metilamino)etossi]fenil]-2-fenil-1-buten-1-il]fenil β-D-glucopiranosidurico

Descrizione:

4-[(1E)-1-[4-[2-(Metilamino)etossifenile]-2-fenile-1-buten-1-ile]fenile]acido β-D-glucopiranosidurónico, con numero CAS 152764-52-8, è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, inclusa una porzione di acido glucopiranosidurónico e un gruppo fenile sostituito. Questo composto presenta proprietà tipiche dei glicosidi, che spesso influenzano la sua solubilità e reattività. La presenza del gruppo metilamino suggerisce un potenziale per attività biologica, possibilmente interagendo con vari bersagli biologici. La struttura del composto indica che potrebbe avere applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci. La sua stereochimica specifica e i gruppi funzionali contribuiscono alle sue potenziali interazioni nei sistemi biologici, rendendolo un argomento di interesse per ulteriori ricerche. Inoltre, il componente di acido glucuronico potrebbe migliorare la sua stabilità metabolica e le vie di escrezione. In generale, questo composto rappresenta un'affascinante intersezione tra chimica organica e farmacologia, giustificando ulteriori indagini sulle sue proprietà e potenziali applicazioni.

Formula: C₃₁H₃₅NO₈

InChI: InChI=1S/C31H35NO8/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(14-10-20)38-18-17-32-2)21-11-15-23(16-12-21)39-31-28(35)26(33)27(34)29(40-31)30(36)37/h4-16,26-29,31-35H,3,17-18H2,1-2H3,(H,36,37)/b25-24+/t26-,27-,28+,29-,31+/m0/s1

InChI key: InChIKey=HSQYCNXRYHIGKV-QXBBUDDSSA-N

SMILES: C(=C(\CC)/C1=CC=CC=C1)(\C2=CC=C(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)C=C2)/C4=CC=C(OCCNC)C=C4

Sinonimi:

• β-D-Glucopyranosiduronic acid, 4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenyl
• 4-[(1E)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl β-D-glucopyranosiduronic acid
• β-D-Glucopyranosiduronic acid, 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenyl, (E)-
• β-D-Glucopyranosiduronic acid, 4-[(1E)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl
• N-Desmethyl-4-hydroxy Tamoxifen O-β-D-glucuronide
• N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture)
• 4-[1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl-d5 β-D-Glucopyranosiduronic Acid
• Tamoxifen Citrate Impurity 26
• Tamoxifen N-Desmethyl 4-Hydroxy β-D-Glucuronide
• N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide
• 4-[1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl β-D-Glucopyranosiduronic Acid
• (E/Z)-Endoxifen Glucuronide

Endoxifen β-D-Glucuronide

CAS: 152764-52-8

Formula: C₃₁H₃₅NO₈

Peso molecolare: 549.62

Ref: 4Z-E-249004

N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture)

Prodotto controllato

CAS: 152764-52-8

Stability Hygroscopic
Applications A novel active metabolite of the anti-cancer drug Tamoxifen (T006000).
References Furr, B., et al.: Pharmacol. Ther., 25, 127 (1984), Leonessa, F., et al.: Cancer Res., 54, 441 (1994), Stearns, V., et al.: Lancet, 360, 1851 (2002), Rae, J., et al.: Pharmacogenetics, 13, 501 (2003), Zheng, Y., et al.: Drug Metab. Dispos., 35, 1942 (2007),

Formula: C₃₁H₃₅NO₈

Colore e forma: Neat

Peso molecolare: 549.61

Ref: TR-D292042

N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide

CAS: 152764-52-8

N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide is a drug product that is used as an analytical reference for the identification and quantification of Metabolites in drug metabolism studies. It is synthesized from 4-hydroxytamoxifen, which has been shown to have antiestrogenic effects and inhibit the growth of estrogen receptor (ER)-positive breast cancer cells. N-Desmethyl-4-hydroxy tamoxifen β-D-glucuronide has been shown to be a metabolite of 4-hydroxytamoxifen. This impurity standard is available in both powder and liquid form with purity levels up to 99%. It can be custom synthesized upon request, with a lead time of 5 weeks.
NDA: N/A

Formula: C₃₁H₃₅NO₈

Purezza: Min. 95%

Peso molecolare: 549.61 g/mol

Ref: 3D-CGA76452

(Z)-4-Hydroxy-N-Desmethyl Tamoxifen (Endoxifen) β-D-Glucuronide

CAS: 152764-52-8

Formula: C₃₁H₃₅NO₈

Peso molecolare: 549.62

Ref: ST-EA-CP-T40027

(Z)-4-Hydroxy-N-Desmethyl Tamoxifen (Endoxifen) β-D-Glucuronide

CAS: 152764-52-8

Formula: C₃₁H₃₅NO₈

Peso molecolare: 549.62

Ref: 4Z-T-0133