
CAS 153437-78-6
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5 prodotti.
O-Desmorpholinopropyl-O-methyl-gefitinib
CAS:Prodotto controllatoApplications O-Desmorpholinopropyl-O-methyl-gefitinib is a anilinoquinazoline derivative of which acts as an inhibitor of tyrosine kinases and found to be allosteric inhibitors of the enzyme frutose 1,6-bisphosphatase. It serves as a lead to further drug design.
References Wright, S. W., Bioorganic & Medicinal Chemistry Letters, 11, 17-21, (2000)Formula:C16H13ClFN3O2Colore e forma:White To Off-WhitePeso molecolare:333.74o-Desmorpholinopropyl-o-methyl-gefitinib
CAS:O-Desmorpholinopropyl-o-methyl-gefitinib is a cytotoxic drug that activates cancer cells. This compound has been shown to be reactive with colon cancer cells, inducing apoptosis and inhibiting the growth of cancer cells in vitro. O-Desmorpholinopropyl-o-methyl-gefitinib induces cell death in colon cancer cells by activating caspase 9 and caspase 3, which are enzymes that cleave proteins that activate other downstream effectors of apoptosis. O-Desmorpholinopropyl-o-methyl-gefitinib also inhibits the proliferation of human colorectal cancer cells (HCT116) and SW620 colon cancer cells.Formula:C16H13ClFN3O2Purezza:Min. 95%Peso molecolare:333.74 g/molRef: ST-EA-CP-G14012
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