CAS 154-93-8

carmustina

Descrizione:

carmustina, con il numero CAS 154-93-8, è un potente agente alchilante utilizzato principalmente nella chemioterapia per il cancro. Appartiene alla classe delle nitrosouree, caratterizzate dalla loro capacità di attraversare la barriera ematoencefalica, rendendole efficaci nel trattamento dei tumori cerebrali e di altre malignità. carmustina è una polvere cristallina bianca a bianco sporco, solubile in solventi organici ma con solubilità limitata in acqua. Il suo meccanismo d'azione implica la formazione di legami incrociati nel DNA, che inibisce la replicazione e la trascrizione del DNA, portando infine alla morte cellulare. carmustina viene tipicamente somministrato per via endovenosa e può essere associato a vari effetti collaterali, tra cui mielosoppressione, nausea e potenziali effetti a lungo termine come tossicità polmonare. A causa della sua reattività e del potenziale di causare malignità secondarie, è essenziale un'attenta gestione e monitoraggio durante il suo utilizzo. In generale, carmustina rimane un componente critico nei regimi di trattamento per specifici tumori, in particolare nei casi in cui altre terapie possono essere meno efficaci.

Formula: C₅H₉Cl₂N₃O₂

InChI: InChI=1/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

InChI key: InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N

SMILES: N(C(NCCCl)=O)(CCCl)N=O

Sinonimi:

• 1,3-Bis(2-Chloroethyl)-1-Nitroso-Urea
• 1,3-Bis(2-chlorethyl)-1-nitrosourea
• 1,3-Bis(2-chloroethyl)-1-nitrosourea
• 1,3-Bis(2-chloroethyl)nitrosourea
• 1,3-Bis(β-chloroethyl)-1-nitrosourea
• Bcnu
• Becenum
• Becenun
• BiCNU
• Carmubris
• Carmustin
• Carmustina
• Dti 015
• Fda 0345
• Gliadel
• Gliadel Wafer
• N,N'-Bis(2-chloroethyl)-N-nitrosourea
• Nitrumon
• Nsc 409962
• Sk 27702
• Sri 1720
• Urea, 1,3-bis(2-chloroethyl)-1-nitroso-
• Urea, N,N'-bis(2-chloroethyl)-N'-nitroso-
• 1,3-bis(beta-chloroethyl)-1-nitrosourea
• n,n’-bis(2-chloroethyl)-n-nitroso-ure
• nci-c04773
• bischlorethylnitrosurea
• bis(2-chloroethyl)nitrosourea
• sk27702
• bischloroethylnitrosourea
• 1,3-bis(2-chloroethyl)-1-nitroso-ure
• fda0345

Carmustine

CAS: 154-93-8

Formula: C₅H₉Cl₂N₃O₂

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 214.05

Ref: 3B-C2634

CARMUSTINE CRS

CAS: 154-93-8

CARMUSTINE CRS

Colore e forma: Powder

Ref: 41-Y0002128

Carmustine

CAS: 154-93-8

Compounds with other nitrogen function, nesoi

Formula: C₅H₉Cl₂N₃O₂

Colore e forma: Light Yellow Powder

Peso molecolare: 213.00718

Ref: 45-1096724

1,3-Bis(2-chloroethyl)nitrosourea

CAS: 154-93-8

Formula: C₅H₉Cl₂N₃O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 214.0499

Ref: IN-DA003DHD

Carmustine

CAS: 154-93-8

Formula: C₅H₉Cl₂N₃O₂

Peso molecolare: 214.05

Ref: 4Z-C-474001

Carmustine

CAS: 154-93-8

Carmustine

Purezza: ≥98%

Peso molecolare: 214.05g/mol

Ref: 54-BUP13658

Carmustine

CAS: 154-93-8

Formula: C₅H₉Cl₂N₃O₂

Purezza: ≥ 95.0%

Colore e forma: Pale yellow to yellow-orange powder, amorphous solid or oily liquid

Peso molecolare: 214.05

Ref: 7W-GP1721

Carmustine

CAS: 154-93-8

Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.

Formula: C₅H₉Cl₂N₃O₂

Purezza: 98% - 99.91%

Colore e forma: Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)

Peso molecolare: 214.05

Ref: TM-T3091

Carmustine

Prodotto controllato

CAS: 154-93-8

Stability Temperature Sensitive
Applications An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),

Formula: C₅H₉Cl₂N₃O₂

Colore e forma: Light Yellow To Light Orange Colour

Peso molecolare: 214.05

Ref: TR-C183875

Carmustine

CAS: 154-93-8

Carmustine is a DNA alkylating agent which also cross-links DNA. As a result Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, mean it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.

Formula: C₅H₉Cl₂N₃O₂

Purezza: Min. 85%

Colore e forma: Powder

Peso molecolare: 214.05 g/mol

Ref: 3D-FC19817

Carmustine - Bio-X ™

CAS: 154-93-8

Carmustine is a DNA alkylating agent which also cross-links DNA. As a result, Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, means it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.

Formula: C₅H₉Cl₂N₃O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 214.05 g/mol

Ref: 3D-BC164289

1,3-BIS(2-CHLOROETHYL)NITROSOUREA

CAS: 154-93-8

Purezza: 97%

Peso molecolare: 214.0500031

Ref: 10-F828460

1,3-Bis(2-chloroethyl-d4)-1-nitrosourea

Prodotto controllato

CAS: 154-93-8

Applications 1,3-Bis(2-chloroethyl-d4)-1-nitrosourea is a useful isotopically labeled compound of Carmustine (C183875)

Formula: C₅D₈HCl₂N₃O₂

Colore e forma: Neat

Peso molecolare: 222.09

Ref: TR-C183877