CAS 154445-77-9

N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofuranil)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetossi)carbonil]-L-ornitina

Descrizione:

La sostanza chimica nota come N5-[[[(2,3-Diidro-2,2,4,6,7-pentametil-5-benzofuranil)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetossi)carbonil]-L-ornitina, con il numero CAS 154445-77-9, è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare. Presenta un gruppo sulfonamide, noto per la sua attività biologica, in particolare nei farmaci. La presenza del moiety benzofurano contribuisce alle sue potenziali interazioni con bersagli biologici, mentre il gruppo fluorenilmetossicarbonile (Fmoc) è comunemente usato nella sintesi di peptidi come gruppo protettivo. Si prevede che il composto mostri caratteristiche specifiche di solubilità, stabilità in determinate condizioni e reattività potenziale a causa dei suoi gruppi funzionali. La sua struttura suggerisce potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di terapie mirate a specifiche vie biologiche. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente le sue proprietà, inclusa la sua farmacocinetica, tossicità ed efficacia nei sistemi biologici.

Formula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1

InChI key: InChIKey=HNICLNKVURBTKV-NDEPHWFRSA-N

SMILES: C(OC(N[C@@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinonimi:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-5-[N′-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido]pentanoic acid
• (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine
• <span class="text-smallcaps">L</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-Arg(pbf)-OH
• FMOC-N-omega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
• Fmoc-<span class="text-smallcaps">L</span>-Arg(Pbf)
• Fmoc-L-Arg(Pbf)-OH
• N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,3-dihydro-1-benzofuran-6-yl)sulfonyl]carbamimidoyl}-D-ornithine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-ornithine
• Na-Fmoc-Nw-Pbf-L-arginine
• L-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 648.78

Ref: 3B-F0729

Nα-Fmoc-N^w-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-arginine, 98%

CAS: 154445-77-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₄H₄₀N₄O₇S

Purezza: 98%

Peso molecolare: 648.78

Ref: 02-H59039

Fmoc-L-Arg(Pbf)-OH

CAS: 154445-77-9

M03398 - Fmoc-L-Arg(Pbf)-OH

Formula: C₃₄H₄₀N₄O₇S

Purezza: 96 %

Colore e forma: Crystalline Powder

Peso molecolare: 648.78

Ref: 10-M03398

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Pbf protection is especially recommended for multiple-Arg- and Trp-containinng peptides. TFA cleavage is best performed in the presence of a silane scavenger.

Formula: C₃₄H₄₀N₄O₇S

Purezza: 99.4081%

Colore e forma: White

Peso molecolare: 648.78

Ref: 01-4089151

FMOC-Arg(Pbf)-OH

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 648.7690

Ref: IN-DA0039MD

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH

Purezza: 98%

Peso molecolare: 648.77g/mol

Ref: 54-BI5913

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Formula: C₃₄H₄₀N₄O₇S

Purezza: ≥ 99.0%

Colore e forma: White to almost white powder

Peso molecolare: 648.77

Ref: 7W-GM9958

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH is an amido-resin that is used in the industrial preparation of polyamides and as a reactive component for the synthesis of various peptide or protein drugs. The polymerisation reaction leads to the formation of a linear chain with a high molecular weight and low viscosity. Fmoc-Arg(Pbf)-OH has been used as an envisaged component for the synthesis of acetylcholine, messenger RNA, and nicotinic acetylcholine receptor. Trifluoroacetic acid is commonly used as a solvent in this process.

Formula: C₃₄H₄₀N₄O₇S

Purezza: Min. 98.0 Area-%

Peso molecolare: 648.77 g/mol

Ref: 3D-FLR-1746-PI

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

The Fmoc-Arg(Pbf)-OH is a cyclic peptide that has been shown to have significant cytotoxicity against human tumor cells. It binds to integrin receptors, which are involved in transcriptional regulation and cellular proliferation. The Fmoc-Arg(Pbf)-OH has been shown to be hypoglycemic and it also possesses redox potential. The chemical biology of this compound is not yet known, but toxicity studies have shown that it is nontoxic in mice.

Formula: C₃₄H₄₀N₄O₇S

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 648.77 g/mol

Ref: 3D-FF15787

Fmoc-Arg(Pbf)-OH

Prodotto controllato

CAS: 154445-77-9

Applications Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Formula: C₃₄H₄₀N₄O₇S

Colore e forma: Neat

Peso molecolare: 648.77

Ref: TR-F604100