CAS 155148-31-5

1,1'-[1,4-Fenilenbis(metilene)]bis[1,4,8,11-tetraazaciclotetradecano]

Descrizione:

1,1'-[1,4-Fenilenbis(metilene)]bis[1,4,8,11-tetraazaciclotetradecano], con numero CAS 155148-31-5, è un composto organico complesso caratterizzato dalla sua struttura unica che incorpora un gruppo fenilenico legato da ponti di metilene a un telaio di tetraazaciclotetradecano. Questo composto presenta più atomi di azoto all'interno della sua struttura ciclica, il che contribuisce alle sue potenziali proprietà chelanti, permettendogli di formare complessi stabili con ioni metallici. La presenza del moiety fenilenico migliora la sua stabilità e può influenzare la sua solubilità e reattività. Tipicamente, tali composti sono di interesse nella chimica di coordinazione e nella scienza dei materiali, in particolare per applicazioni in catalisi, somministrazione di farmaci o come leganti in strutture metal-organiche. Il componente tetraazaciclotetradecano suggerisce una potenziale attività biologica, rendendolo un candidato per ulteriori indagini in chimica medicinale. In generale, le caratteristiche strutturali del composto indicano una natura versatile, adatta per varie applicazioni sia nella ricerca accademica che in contesti industriali.

Formula: C₂₈H₅₄N₈

InChI: InChI=1/C28H54N8.8ClH.2H2O/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H;2*1H2

InChI key: InChIKey=UEUPDYPUTTUXLJ-UHFFFAOYSA-N

SMILES: C(C1=CC=C(CN2CCCNCCNCCCNCC2)C=C1)N3CCCNCCNCCCNCC3.Cl

Sinonimi:

• 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis-1,4,8,11-Tetraazacyclotetradecane Octahydrochloride Dihydrate
• 1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)
• 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, octahydrochloride
• AMD 3100 octahydrochloride
• Amd 3100
• Jm 3100
• Plerixafore 8HCl
• Sid 791
• Bicyclam
• JM3100, SID791, 1,1μ-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane octahydrochloride
• Plerixafor hcl
• amd3100 octahydrochloride hydrate
• Plerixafor 8HCl (AMD3100 8HCl)
• 1,1'-[1,4-PHENYLENEBIS(METHYLENE)]BIS-1,4,8,11-TETRAAZACYCLOTETRADECANE OCTAHYDROCHLORIDE
• Plerixafor 8HCl
• Plerixafor HCL(JM 3100)
• 1,1'-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane]
• JM3100
• AMD 3100 octahydrochloride, >=98%
• InSolution? CXCR4 Antagonist I, AMD3100
• Plerixafor (octahydrochloride)
• AMD 3100 octahydrochloride(8HCl)
• AMD3100 8HCl
• Plerixafor 8HCl (AMD3100)
• Plerixafor hydrochloride
• SID791 octahydrochloride
• AMD 3100 octahydroch
• Plerixafor hydrochloride salt
• Plerixafor Hydrochloride (1:8)
• Plerixafor 8HCl (AMD3100 8HCl) USP/EP/BP
• AMD3100 OCTAHYDROCHLORIDE
• Plerixafor(SynonyM: AMD3100 octahydrochloride hydrate)
• 1,4-Bis[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]benzene Octahydrochloride
• AMD3100 HCl
• AMD3100 OCTAHYDROCHLORIDE;AMD-3100; AMD 3100
• CS-907
• BISCYCLAM
• CXCR4 Antagonist I, AMD3100
• AMD3100 hydrate octahydrochloride
• Plerixafor-d8 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride, min. 95 % (NMR)
• InSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem
• SID791
• AMD3100
• JM 3100 8HCl
• 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride hydrate
• JM3100 octahydrochloride
• Plerixafor 8HCl (DB06809)
• AMD3100 OCTAHYDROCHLORIDE HYDRATE ANHYDROUS
• CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem

AMD-3100 Octahydrochloride

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 794.46

Ref: 3B-P2620

1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

CAS: 155148-31-5

Formula: C₂₈H₆₂Cl₈N₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 794.4695

Ref: IN-DA001NNI

AMD3100 octahydrochloride hydrate

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl·xH₂O

Purezza: ≥ 97.0% (anhydrous basis)

Colore e forma: White or off-white powder

Peso molecolare: 794.47 (anhydrous)

Ref: 7W-GK7176

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride

Purezza: ≥95%

Peso molecolare: 794.46g/mol

Ref: 54-BUP13171

Plerixafor-d8 8HCl

CAS: 155148-31-5

Formula: C₂₈H₄₆D₈N₈·8HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 510.84 8 36.46

Ref: 4Z-P-557

Plerixafor 8HCl

CAS: 155148-31-5

Formula: C₂₈H₅₄N₈·8HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 502.80 8 36.46

Ref: 4Z-P-551

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

CAS: 155148-31-5

1,4-Bis((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzene Octahydrochloride

Purezza: 99%

Peso molecolare: 794.47g/mol

Ref: 54-OR1009221

Plerixafor octahydrochloride

CAS: 155148-31-5

Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.

Formula: C₂₈H₆₂Cl₈N₈

Purezza: 98.01% - 99.79%

Colore e forma: Solid

Peso molecolare: 794.46

Ref: TM-T1776L

AMD 3100 octahydrochloride

CAS: 155148-31-5

Antagonises CXCR4 selectively by blocking Ca2+ release (IC50 from 0.02 to 0.13 µM). Studied in SDF-1/CFXCR4-dependent functions in HIV, rheumatoid arthritis and breast cancer metastasis. Enhances mobilization of hematopoietic stem cells (HSCs) and Hematopoietic progenitor cells (HPCs) for re-populating hematopoietic progenitors for transplants in vivo and attenuates cocaine-induced locomotor activation.

Formula: C₂₈H₆₂Cl₈N₈

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 794.47 g/mol

Ref: 3D-FA148913

Plerixafor octahydrochloride

CAS: 155148-31-5

Purezza: 99%

Peso molecolare: 794.46

Ref: 10-F979582

Plerixafor Hydrochloride (1:8)

Prodotto controllato

CAS: 155148-31-5

Stability Hygroscopic
Applications Plerixafor Hydrochloride (1:8), is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients. It is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).
References Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003), Chigaev, A., et al.: J. Immunol. 178, 6828 (2007), Kiel, M., et al.: Cell Stem Cell, 1, 204 (2007),

Formula: C₂₈H₅₄N₈·8ClH

Colore e forma: Neat

Peso molecolare: 794.47

Ref: TR-P580505