CAS 15690-38-7

acido (6R,7R)-7-ammino-3-(idrossimetil)-8-osso-5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico

Descrizione:

La sostanza chimica nota come acido (6R,7R)-7-ammino-3-(idrossimetil)-8-osso-5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico, con il numero CAS 15690-38-7, è un composto biciclico che presenta una struttura ad anello di tiazolidina. Questo composto è caratterizzato dalla presenza di un gruppo amminico, un gruppo idrossimetilico e un gruppo funzionale acido carbossilico, contribuendo alla sua potenziale attività biologica. La stereochimica indicata dalla configurazione (6R,7R) suggerisce disposizioni spaziali specifiche degli atomi che possono influenzare le interazioni del composto con obiettivi biologici. Il suo gruppo oxo e il componente tiazolidina suggeriscono una reattività potenziale e interazioni con vari sistemi biologici. Questo composto è di interesse nella chimica medicinale, in particolare nello sviluppo di antibiotici, a causa delle sue somiglianze strutturali con agenti antibiotici noti. La struttura biciclica unica può anche conferire proprietà farmacologiche specifiche, rendendolo oggetto di ricerca nel design e nello sviluppo di farmaci.

Formula: C₈H₁₀N₂O₄S

InChI: InChI=1S/C8H10N2O4S/c9-4-6(12)10-5(8(13)14)3(1-11)2-15-7(4)10/h4,7,11H,1-2,9H2,(H,13,14)/t4-,7-/m1/s1

InChI key: InChIKey=BQIMPGFMMOZASS-CLZZGJSISA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CO)[H]

Sinonimi:

• (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-Amino-3-hydroxymethylceph-3-em-4-carboxylic acid
• 3-Hydroxymethyl-7-aminoceph-3-em-4-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans)-
• 7-Amino-3-(Hydroxymethyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• 7-Amino-3-hydoxymethyl-3-cephem-carboxylic acid
• 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid
• 7-Amino-deacetylcephalosporanic acid
• 7β-Amino-3-(hydroxymethyl)-3-cephem-4-carboxylic acid
• Deacetyl-7-aminocephalosporanic acid

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 230.2410

Ref: IN-DA007HQ7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

CAS: 15690-38-7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

Purezza: 98%

Peso molecolare: 230.24g/mol

Ref: 54-OR1029784

Cefazedone Impurity 11

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Colore e forma: Off-White Solid

Peso molecolare: 230.24

Ref: 4Z-C-108012

Deacetyl-7-aminocephalosporanic acid

CAS: 15690-38-7

Deacetyl-7-aminocephalosporanic acid serves as a crucial intermediate in the production of β-lactam broad-spectrum cephalosporin antibiotics.

Formula: C₈H₁₀N₂O₄S

Purezza: 99.97%

Colore e forma: Solid

Peso molecolare: 230.24

Ref: TM-T21006

7-Aminodeacetylcephalosporanic Acid

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 230.24

Ref: 3B-A2878

7-Amino-deacetylcephalosporanic Acid

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Ref: TR-TRC-A603420

7-Amino-deacetylcephalosporanic Acid

Prodotto controllato

CAS: 15690-38-7

Applications Intermediate in the semi-synthetic cephalosporins synthesis. Found in Acremonium chrysogenum.
References Fukagawa, M. et al.; Agr. Biol. Chem. 55, 2163 (1991)

Formula: C₈H₁₀N₂O₄S

Colore e forma: Neat

Peso molecolare: 230.24

Ref: TR-A603420

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 230.24

Ref: 10-F243053

Cefazedone Impurity 1

CAS: 15690-38-7

Formula: C₈H₁₀N₂O₄S

Peso molecolare: 230.24

Ref: ST-EA-CP-C209001

7-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid

CAS: 15690-38-7

Cefepime is a broad-spectrum antibiotic that belongs to the group of β-lactam antibiotics. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit, which prevents bacterial protein synthesis. Cefepime hydrochloride is a prodrug that is hydrolyzed in vivo to cefepime, its active form. Cefepime hydrochloride has been shown to inhibit the production of subtilisin and acylase, enzymes involved in the digestion of proteins and fats. The hydrolysis reaction also increases the solubility of cefepime. The crystallization process for cefepime hydrochloride involves heating with organic solvents such as methanol and ethanol. This process can be used for purification and isolation from impurities.

Formula: C₈H₁₀N₂O₄S

Purezza: Min. 95%

Peso molecolare: 230.24 g/mol

Ref: 3D-FA36388