CAS 158442-41-2

N-cbz-ile-glu(O-T-butil)-ala-leucinal

Descrizione:

N-cbz-ile-glu(O-T-butil)-ala-leucinal, con il numero CAS 158442-41-2, è un composto sintetico che appartiene alla classe dei peptidi e dei derivati dei peptidi. Presenta un gruppo protettivo Cbz (benzyloxycarbonile), comunemente utilizzato nella sintesi dei peptidi per proteggere il gruppo amminico dell'aminoacido. Il composto contiene isoleucina (ile), acido glutammico (glu) con una modifica di estere tert-butile, alanina (ala) e leucina (leucinal), indicando una struttura complessa che può mostrare specifiche attività biologiche. La presenza del gruppo tert-butile aumenta la lipofilia del residuo di acido glutammico, influenzando potenzialmente la solubilità e la permeabilità del composto. Questo composto potrebbe essere di interesse nella chimica medicinale e nello sviluppo di farmaci, in particolare nella progettazione di terapie basate su peptidi. Le sue caratteristiche, inclusa stabilità, reattività e attività biologica, dipenderebbero dal contesto specifico del suo utilizzo e dalle condizioni in cui viene studiato. Ulteriori ricerche sarebbero necessarie per chiarire il suo pieno potenziale e le applicazioni in vari campi.

Formula: C₃₂H₅₀N₄O₈

Sinonimi:

• Proteasome Inhibitor I
• N-[(Phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-tert-butylester-N-[(1S)-1-formyl-3-methylbutyl]-L-alaninamide
• PROTEASOME INHIBITOR I USP/EP/BP
• N-CBZ-ILE-GLU(O-T-BUTYL)-ALA-LEUCINAL
• Z-IE(OTBU)AL-CHO
• arbobenzoxy-l-isoleucyl-gamma-t-butyl-l-glutamyl-l-alanyl-l-leucinal
• M.W. 618.77 C32H50N4O8
• Z-ILE-GLU(OBUT)-ALA-LEU-H
• PSI PROTEASOME INHIBITOR I
• CBZ-Ile-Glu(OtBu)-Ala-Leu-aldehyde
• ProteasoMe Inhibitor 1
• Z-ILE-GLU(OTBU)-ALA-LEU-ALDEHYDE
• Z-ILE-GLU(OTBU)-ALA-LEU-CHO
• PROTEASOME INHIBITOR I (ALDEHYDE)
• CS-1340
• Cbz-Ile-Glu(OtBu)-Ala-Leu-al
• z-ile-glu(o-t-butyl)-ala-leucinal
• PROTEASOME INHIBITOR PSI
• Z-ILE-GLU(OBUT)-ALA-LEU-H (ALDEHYDE)
• PROTEASOME INHIBITOR I ;Z-ILE-GLU(OTBU)-ALA-LEU-CHO
• BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL
• L-AlaninaMide, N-[(phenylMethoxy)carbonyl]-L-isoleucyl-L-a-glutaMyl-N-[(1S)-1-forMyl-3 -Methylbutyl]-, 1,1-diMethylethyl ester
• PSI
• CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL
• L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester
• N-Cb
• N-carbobenzyloxy-Ile-Glu(O-tert-butyl)-Ala-leucinal

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

CAS: 158442-41-2

Z-IE(OtBu)AL-CHO is an inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex (MPC; 20S proteasome) in HT4 cells. It is the first inhibitor reported so far which can cause accumulation of ubiquitinylated proteins in neuronal cells. Furthermore, this compound induced massive apoptosis in murine leukaemia L1210 cells. Therefore, proteasome inhibitors may be considered as potential anti-neoplastic agents.

Formula: C₃₂H₅₀N₄O₈

Purezza: ≥ 95%

Colore e forma: White

Peso molecolare: 618.77

Ref: 01-4026408

L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester

CAS: 158442-41-2

Formula: C₃₂H₅₀N₄O₈

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 618.7614

Ref: IN-DA001Q6O

Z-Ile-Glu(O-t-butyl)-Ala-Leucinal

CAS: 158442-41-2

Formula: C₃₂H₅₀N₄O₈

Purezza: ≥ 90.0%

Colore e forma: White solid

Peso molecolare: 618.76

Ref: 7W-GK8272

Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Dap(Dnp)-NH2

CAS: 158442-41-2

Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Dap(Dnp)-NH2 is a synthetic peptide that binds to the toll receptor. The binding of this peptide leads to the signal pathways, which are responsible for the body formation. Abz-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser Arg Dap (Dnp) -NH2 has been shown to have an antiinflammatory effect in rats. This peptide also has a dna binding activity and can be used as a marker for granule neurons in the brain.

Formula: C₅₉H₉₃N₂₃O₂₀

Purezza: Min. 95%

Peso molecolare: 1,444.54 g/mol

Ref: 3D-SDP-3818-PI

Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde)

CAS: 158442-41-2

inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex in HT4 cells.  Causes accumulation of ubiquitinylated proteins in neuronal cells.

Formula: C₃₂H₅₀N₄O₈

Purezza: Min. 95%

Peso molecolare: 618.76 g/mol

Ref: 3D-IAT-3169-V

Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde)

CAS: 158442-41-2

Please enquire for more information about Z-Ile-Glu(OtBu)-Ala-Leu-H (aldehyde) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₃₂H₅₀N₄O₈

Peso molecolare: 618.76 g/mol

Ref: 3D-IAT-3169

PSI

CAS: 158442-41-2

PSI is a proteasome inhibitor.

Formula: C₃₂H₅₀N₄O₈

Purezza: 97% - 98.33%

Colore e forma: Solid

Peso molecolare: 618.76

Ref: TM-T21510

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

CAS: 158442-41-2

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, also known as ZILEAL, is a potent immunosuppressant that binds to the Toll-like receptor (TLR) and inhibits NF-κB binding activity. It has been shown to reduce the activation of macrophages by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα), IL-1β, and IL-6. This drug has been shown to inhibit HIV replication in vitro and was also found to have an antiviral effect against herpes simplex virus type 1 in vivo. ZILEAL also inhibits dsDNA binding activity, which may have potential applications in cancer treatment.

Formula: C₃₂H₅₀N₄O₈

Purezza: Min. 95%

Peso molecolare: 618.76 g/mol

Ref: 3D-FI111570