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CAS 158584-09-9

:

7-metossicumarina-4-acetil-arg-pro-*lis-pro-val-G

Descrizione:
7-metossicumarina-4-acetil-arg-pro-*lis-pro-val-G, identificato dal suo numero CAS 158584-09-9, è un composto sintetico che combina una parte di cumarina con una sequenza peptidica. La struttura della cumarina è nota per le sue proprietà fluorescenti, rendendola utile in varie applicazioni biochimiche, inclusa come sonda fluorescente nell'imaging cellulare. La presenza del gruppo acetile ne migliora la solubilità e la stabilità, mentre la sequenza peptidica, che include aminoacidi come arginina, prolina, lisina e valina, può conferire specifiche attività biologiche o facilitare interazioni con obiettivi biologici. Questo composto è spesso studiato nel contesto dello sviluppo di farmaci e della biologia molecolare a causa delle sue potenziali applicazioni terapeutiche e della sua capacità di modulare processi biologici. La sua struttura unica consente l'esplorazione delle sue proprietà farmacologiche, inclusa la sua efficacia e meccanismo d'azione in vari sistemi biologici. In generale, 7-metossicumarina-4-acetil-arg-pro-*lis-pro-val-G rappresenta un composto versatile con significative implicazioni nella ricerca e nella medicina.
Formula:C78H110N22O20
InChI:InChI=1/C78H110N22O20/c1-5-16-53(68(106)95-58(37-45-42-88-50-18-7-6-17-48(45)50)71(109)92-54(21-12-33-86-77(81)82)69(107)90-52(67(80)105)19-9-11-32-85-51-28-25-46(99(115)116)40-61(51)100(117)118)91-70(108)55(29-30-64(102)103)93-74(112)66(43(2)3)96-73(111)60-24-15-36-98(60)76(114)57(20-8-10-31-79)94-72(110)59-23-14-35-97(59)75(113)56(22-13-34-87-78(83)84)89-63(101)38-44-39-65(104)120-62-41-47(119-4)26-27-49(44)62/h6-7,17-18,25-28,39-43,52-60,66,85,88H,5,8-16,19-24,29-38,79H2,1-4H3,(H2,80,105)(H,89,101)(H,90,107)(H,91,108)(H,92,109)(H,93,112)(H,94,110)(H,95,106)(H,96,111)(H,102,103)(H4,81,82,86)(H4,83,84,87)/t52-,53-,54-,55-,56-,57-,58-,59-,60-,66-/m0/s1
SMILES:CCC[C@@H](C(=N[C@@H](Cc1c[nH]c2ccccc12)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCCCNc1ccc(cc1N(=O)=O)N(=O)=O)C(=N)O)O)O)O)N=C([C@H](CCC(=O)O)N=C([C@H](C(C)C)N=C([C@@H]1CCCN1C(=O)[C@H](CCCCN)N=C([C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N=C(Cc1cc(=O)oc2cc(ccc12)OC)O)O)O)O)O
Sinonimi:
  • Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2
  • Nff 3
  • ((7-Methoxycoumarin-4-yl)acetyl)arginyl-prolyl-lysyl-prolyl-valyl-glutamyl-norvalyl-tryptophyl-arginyl-(2,4-dinitrophenyl)lysinamide
  • Mca-arg-pro-lys-pro-val-glu-nva-trp-arg-lys(dnp)-NH2
  • N2-((7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysinamide
  • L-Lysinamide, N2-((7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-
Ordinare per
Purezza (%)
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100
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50
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90
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95
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100
3 prodotti.
  • Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂
    Bachem
    + Info

    Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂

    CAS:
    The FRET substrate Mca-RPKPVE-Nva-WRK(Dnp) amide was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2.
    Formula:C78H110N22O20
    Purezza:96.18%
    Colore e forma:Powder
    Peso molecolare:1675.87

    Ref: 01-4030842

    1mg
    350,00€
    5mg
    1.344,00€
  • MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂
    Biosynth
    + Info

    MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂

    CAS:
    <p>MOCA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 is a synthetic peptide that interacts with the nicotinic acetylcholine receptor and is a potent agonist. MOCA was found to be a potent activator of the nicotinic acetylcholine receptor, as well as an inhibitor of ligand binding. The affinity for binding to the receptor was found to be high, with an inhibition constant (Ki) of 0.06 μM. It has been shown to inhibit ion channels and ligand binding in cell biology experiments. MOCA can also be used as a research tool for studying protein interactions and receptors.</p>
    Formula:C78H110N22O20
    Purezza:Min. 95%
    Peso molecolare:1,675.8 g/mol

    Ref: 3D-SMO-3168-V

    1mg
    466,00€
  • Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt
    Biosynth
    + Info

    Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt

    CAS:
    Please enquire for more information about Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Formula:C78H110N22O20
    Purezza:Min. 95%
    Peso molecolare:1,675.84 g/mol

    Ref: 3D-FM110916

    1mg
    860,00€
    2mg
    1.019,00€
    5mg
    2.078,00€