CAS 15876-67-2

bromuro di distigmina

Descrizione:

bromuro di distigmina è un composto di ammonio quaternario sintetico utilizzato principalmente come farmaco per trattare la miastenia gravis, un disturbo neuromuscolare caratterizzato da debolezza nei muscoli scheletrici. Funziona come un inibitore dell'acetilcolinesterasi, migliorando l'azione dell'acetilcolina alle giunzioni neuromuscolari, migliorando così la contrazione e la forza muscolare. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, il che facilita la sua somministrazione. La sua struttura chimica include due gruppi di ammonio quaternario, contribuendo alla sua attività farmacologica. bromuro di distigmina viene tipicamente somministrato per via orale o tramite iniezione, e i suoi effetti possono essere osservati relativamente rapidamente, rendendolo efficace per gestire i sintomi di debolezza muscolare. Tuttavia, può anche causare effetti collaterali come disturbi gastrointestinali, aumento della salivazione e crampi muscolari. Come per qualsiasi farmaco, un attento dosaggio e monitoraggio sono essenziali per minimizzare gli effetti avversi e garantire l'efficacia terapeutica.

Formula: C₂₂H₃₂N₄O₄·2Br

InChI: InChI=1/C22H32N4O4.2BrH/c1-23-13-9-11-19(17-23)29-21(27)25(3)15-7-5-6-8-16-26(4)22(28)30-20-12-10-14-24(2)18-20;;/h9-14,17-18H,5-8,15-16H2,1-4H3;2*1H/q+2;;/p-2

InChI key: InChIKey=GJHSNEVFXQVOHR-UHFFFAOYSA-L

SMILES: O(C(N(CCCCCCN(C(OC1=C[N+](C)=CC=C1)=O)C)C)=O)C2=C[N+](C)=CC=C2.[Br-]

Sinonimi:

• 3,3'-{Hexane-1,6-Diylbis[(Methylcarbamoyl)Oxy]}Bis(1-Methylpyridinium) Dibromide
• 3-Hydroxy-1-methylpyridinium bromide, hexamethylenebis[methylcarbamate]
• Bc 51
• Distigmine Br
• Distigmine dibromide
• Hexamarium
• Hexamarium bromide
• N,N′-Hexamethylenebis(3-N-methylcarbamoxy-1-methylpyridine)dibromide
• Pyridinium, 3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)
• Pyridinium, 3,3′-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, dibromide
• Pyridinium, 3-hydroxy-1-methyl-, bromide, hexamethylenebis[methylcarbamate] (2:1)
• Ubretid
• Ubritil
• BC51
• (1-methylpyridin-1-ium-3-yl) N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonylamino]hexyl]carbamate dibromide
• 3-Hydroxy-1-methylpyridinium
• (1-methylpyridin-1-ium-3-yl) N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonyl-amino]hexyl]carbamate dibromide
• distigmine bromide
• N-methyl-N-[6-[methyl-(1-methylpyridin-1-ium-3-yl)oxycarbonyl-amino]hexyl]carbamic acid (1-methylpyridin-1-ium-3-yl) ester dibromide
• 3,3'-(((Hexane-1,6-diylbis(methylazanediyl))bis(carbonyl))bis(oxy))bis(1-methylpyridin-1-ium) bromide
• Denispan
• Ubtec
• Distigmine

Distigmine Bromide

CAS: 15876-67-2

Colore e forma: Neat

Ref: 61-FOR1167.00

Pyridinium, 3,3'-[1,6-hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methyl-, bromide (1:2)

CAS: 15876-67-2

Formula: C₂₂H₃₂Br₂N₄O₄

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 576.3219

Ref: IN-DA001QU9

Distigmine Bromide

CAS: 15876-67-2

Formula: C₂₂H₃₂N₄O₄·2Br

Colore e forma: White To Off-White Solid

Peso molecolare: 416.52 2x79.90

Ref: 4Z-D-137001

Distigmine Bromide-d6

Prodotto controllato

CAS: 15876-67-2

Applications Distigmine Bromide-d6 is the isotope labelled analog of Distigmine Bromide (D493530); a cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugaya, K.,e t. al.: Int. J. Urology, 19, 480 (2012)

Formula: C₂₂H₂₆D₆N₄O₄•2(Br)

Colore e forma: Neat

Peso molecolare: 582.36

Ref: TR-D493532

Distigmine Bromide

Prodotto controllato

CAS: 15876-67-2

Stability Hygroscopic, Temperature Sensitive
Applications Distigmine Bromide is a cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugaya, K.,e t. al.: Int. J. Urology, 19, 480 (2012)

Formula: C₂₂H₃₂N₄O₄·2Br

Colore e forma: Neat

Peso molecolare: 576.32

Ref: TR-D493530

Distigmine bromide

CAS: 15876-67-2

Distigmine bromide is a cholinergic agent that can be used to treat the symptoms of urinary incontinence. It is also used to treat underactive bladders and the symptoms associated with it. Distigmine bromide belongs to pharmacological agents and is an acetylcholinesterase inhibitor. This drug is administered by mouth, and its effects are long-lasting. It can be used for the treatment of psychotic disorders as well as for diagnosis of bladder disease.

Formula: C₂₂H₃₂N₄O₄•(Br)₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 576.32 g/mol

Ref: 3D-FD42999

Distigmine Bromide

CAS: 15876-67-2

Distigmine Bromide is an acetylcholinesterase inhibitor. It is used for the treatment of underactive neurogenic bladder and myasthenia gravis.

Formula: C₂₂H₃₂BrN₄O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 496.42

Ref: TM-T7825