CAS 160844-75-7

Etil 2-[3-ciano-4-(2-metilpropossi)fenile]-4-metil-5-tiazolecarbossilato

Descrizione:

Etil 2-[3-ciano-4-(2-metilpropossi)fenile]-4-metil-5-tiazolecarbossilato, con numero CAS 160844-75-7, è un composto organico sintetico caratterizzato dalla sua struttura complessa, che include un anello di tiazolo, un gruppo ciano e un gruppo funzionale di estere etilico. Questo composto tipicamente mostra proprietà associate sia a derivati del tiazolo che a composti aromatici, come una solubilità moderata in solventi organici e una reattività potenziale dovuta alla presenza del gruppo ciano. La parte di tiazolo può contribuire all'attività biologica, rendendolo di interesse nella ricerca farmaceutica. La sua struttura molecolare suggerisce applicazioni potenziali in chimica medicinale, in particolare nello sviluppo di nuovi agenti terapeutici. Inoltre, la presenza del gruppo 2-metilpropossido può influenzare la sua lipofilia e le proprietà farmacocinetiche complessive. Come per molti composti organici, i dati di sicurezza e le precauzioni di manipolazione devono essere considerati, poiché la tossicità specifica e l'impatto ambientale di questo composto dovrebbero essere valutati attraverso studi empirici.

Formula: C₁₈H₂₀N₂O₃S

InChI: InChI=1S/C18H20N2O3S/c1-5-22-18(21)16-12(4)20-17(24-16)13-6-7-15(14(8-13)9-19)23-10-11(2)3/h6-8,11H,5,10H2,1-4H3

InChI key: InChIKey=OGAZOYHQFBSRMC-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1SC(=NC1C)C2=CC(C#N)=C(OCC(C)C)C=C2

Sinonimi:

• 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylic Acid Ethyl Ester
• 2-[3-Cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-Thiazole Carboxylic Acid Ethyl Ester
• 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester
• Ethyl 2-(3-Cyano-4-IsobutoxyPhenyl)-4-MethylThiazole-5-Carboxylate
• Ethyl 2-[3-Cyano-4-(2-Methylpropoxy)Phenyl]-4-Methyl-1,3-Thiazole-5-Carboxylate
• Ethyl 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-Thiazolecarboxylate
• Febuxostat N-5
• Febuxostat intermediates-2
• Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, ethyl ester

CAS: 160844-75-7

Formula: C₁₈H₂₀N₂O₃S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 344.4280

Ref: IN-DA001VEX

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS: 160844-75-7

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Purezza: 98%

Peso molecolare: 344.43g/mol

Ref: 54-OR96123

Febuxostat Impurity 3

CAS: 160844-75-7

Formula: C₁₈H₂₀N₂O₃S

Colore e forma: Off-White Solid

Peso molecolare: 344.43

Ref: 4Z-F-3912

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS: 160844-75-7

Formula: C₁₈H₂₀N₂O₃S

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 344.43

Ref: 3B-E1414

Febuxostat Ethyl Ester (2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester)

CAS: 160844-75-7

Colore e forma: Neat

Ref: 86-MM3552.02

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS: 160844-75-7

Applications Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)

Formula: C₁₈H₂₀N₂O₃S

Colore e forma: Neat

Peso molecolare: 344.43

Ref: TR-E907780

Febuxostat Ethyl ester impurity

CAS: 160844-75-7

Formula: C₁₈H₂₀N₂O₃S

Peso molecolare: 344.43

Ref: ST-EA-CP-F7011

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS: 160844-75-7

Formula: C₁₈H₂₀N₂O₃S

Purezza: ≥98%

Colore e forma: Liquid, No data available.

Peso molecolare: 344.43

Ref: 10-F213564

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS: 160844-75-7

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate (ECIT) is a derivative of formyl that has been used as a solvent for industrial and laboratory purposes. ECIT is an amorphous substance with the chemical formula CH3COC6H2CH2COCH=N(C=O)C6H4CN. The compound has been quantified in various solvents, such as n-butyl alcohol and acetonitrile. ECIT is a colorless liquid that boils at 140° C. It has a formyl group and an alkynyl group, which are both reactive groups that can be used to synthesize other compounds. ECIT also contains two stereoisomers: the erythro isomer and the threo isomer. The erythro isomer has the structural formula of CH3COC6H2CH

Purezza: Min. 95%

Ref: 3D-FE45493