CAS: 1610353-18-8 - Immunoglobulin G2, anti-(human interleukin 23) (human monoclonal MEDI2070 heavy chain), disulfide with human monoclonal MEDI2070 λ-chain, dimer

Formula: Unspecified

Sinonimi:

• MEDI 2070
• AMG 139
• Immunoglobulin G2, anti-(human interleukin 23) (human monoclonal MEDI2070 heavy chain), disulfide with human monoclonal MEDI2070 λ-chain, dimer
• Immunoglobulin G2-lambda, anti-(human interleukin-23 (IL-23)); human monoclonal antibody:γ2 heavy chain (1-450) [human VH (Homo sapiens IGHV3-33*01 (99%) ?(IGHD)-IGHJ3*02) [8.8.17] (1-124) -Homo sapiens IGHG2*01 (125-450)] (138-216′)-disulfide with lambda light chain (1′-217′) [human V-LAMBDA (Homo sapiens IGLV1-40*01 (96%) -IGLJ3*02 (92%)) [9.3.11] (1′-111′) -Homo sapiens IGLC2*01 (112′-217′)], dimer (226-226′′:227227′′:230-230′′:233-233′′)-tetrakisdisulfide
• Brazikumab

Brazikumab

CAS: 1610353-18-8

Brazikumab (AMG 139), a human IgG2 monoclonal antibody, targets IL-23 p19 subunit, KD 0.138 nM, …

• Colore e forma: Solid

Brazikumab

CAS: 1610353-18-8

Anti-IL23 human monoclonal antibody; used as a treatment of Crohn's disease