CAS 161796-78-7

Esomeprazolo sodico

Descrizione:

Esomeprazolo sodico è un inibitore della pompa protonica (PPI) utilizzato principalmente per trattare la malattia da reflusso gastroesofageo (GERD) e altre condizioni associate alla produzione eccessiva di acido gastrico. È l'S-enantiomero dell'omeprazolo, che ne migliora l'efficacia e la biodisponibilità. Questo composto è tipicamente presentato come un sale sodico, che ne migliora la solubilità in soluzioni acquose. Esomeprazolo sodico agisce inibendo irreversibilmente l'enzima H+/K+ ATPasi nelle cellule parietali gastriche, portando a una significativa riduzione della secrezione di acido gastrico. È caratterizzato dalla sua forma di polvere cristallina bianca a bianco sporco, con una formula molecolare che include carbonio, idrogeno, azoto, ossigeno e sodio. La sostanza è generalmente stabile in condizioni normali, ma deve essere conservata lontano da umidità e luce per mantenere la sua potenza. Comunemente somministrato per via orale, Esomeprazolo sodico è ben assorbito nel tratto gastrointestinale, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione. La sua farmacocinetica può essere influenzata da fattori come l'assunzione di cibo e le variazioni metaboliche individuali.

Formula: C₁₇H₁₉N₃O₃S·Na

InChI: InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1

InChI key: InChIKey=HVAJOLFRLWQQQL-JIDHJSLPSA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]

Sinonimi:

• (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• (S)-Omeprazole sodium
• 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt, (S)-
• 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
• 1H-benzimidazole, 5-Methoxy-2-[[(4-Methoxy-3,5-dimethyl-2-PYRIDINYL)methyl]sulfinyl]-, sodium salt
• 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
• Bis[5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)Methylsulfinyl]Benzimidazol-1-Yl]Magnesium
• Esomeprazole Na
• Esomeprazole sodium salt
• Esomeprazoleandsalts
• H 199/18 sodium
• Sodium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide
• sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-2,3-dihydrobenzimidazol-1-ide

Esomeprazole Sodium

CAS: 161796-78-7

Colore e forma: Neat

Ref: 61-FOR3373.00

ESOMEPRAZOLE SODIUM CRS

CAS: 161796-78-7

ESOMEPRAZOLE SODIUM CRS

Colore e forma: Added Added

Ref: 41-Y0002075

Esomeprazole Sodium

CAS: 161796-78-7

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₁₈N₃NaO₃S

Colore e forma: White Off-White Powder

Peso molecolare: 367.09666

Ref: 45-1249790

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purezza: %

Colore e forma: Solid

Peso molecolare: 367.3979

Ref: IN-DA001VVZ

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium

Purezza: ≥98%

Peso molecolare: 367.4g/mol

Ref: 54-BUP10558

Esomeprazole sodium salt hydrate

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purezza: (Titration) ≥ 98.0%

Colore e forma: White to off-white or pale yellow crystalline powder

Peso molecolare: 367.40

Ref: 7W-GP5980

Esomeprazole Sodium Salt

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃O₃S·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 344.42 22.99

Ref: 4Z-O-029

Esomeprazole Sodium

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃O₃S·Na

Colore e forma: Neat

Peso molecolare: 367.40

Ref: 86-MM3373.00

(S)-Omeprazole Sodium Salt

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 367.40

Ref: 3B-O0560

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.

Formula: C₁₇H₁₈N₃O₃S·Na

Purezza: 98.17% - >99.99%

Colore e forma: Solid

Peso molecolare: 367.4

Ref: TM-T2686L

Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

CAS: 161796-78-7

Purezza: 95.0%

Peso molecolare: 367.3999938964844

Ref: 10-F219014

Esomeprazole sodium

CAS: 161796-78-7

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Formula: C₁₇H₁₈N₃NaO₃S

Purezza: (%) Min. 95%

Colore e forma: Powder

Peso molecolare: 367.4 g/mol

Ref: 3D-IM58097

Esomeprazole sodium - EP

CAS: 161796-78-7

Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.

Formula: C₁₇H₁₈N₃NaO₃S

Purezza: Min. 95%

Colore e forma: White/Off-White Solid

Peso molecolare: 367.4 g/mol

Ref: 3D-IE177087

Esomeprazole Sodium

CAS: 161796-78-7

Formula: C₁₇H₁₉N₃O₃SNa

Peso molecolare: 345.4 : 23.0

Ref: ST-EA-CP-E14021