CAS 161973-10-0

esomeprazolo magnesio

Descrizione:

esomeprazolo magnesio è un inibitore della pompa protonica (PPI) utilizzato principalmente per trattare la malattia da reflusso gastroesofageo (GERD) e altre condizioni associate a una produzione eccessiva di acido gastrico. È il sale di magnesio dell'esomeprazolo, che è l'S-enantiomero dell'omeprazolo. Questo composto agisce inibendo irreversibilmente l'enzima H+/K+ ATPasi nelle cellule parietali gastriche, portando a una diminuzione della secrezione di acido gastrico. esomeprazolo magnesio viene tipicamente somministrato per via orale ed è noto per la sua migliore biodisponibilità rispetto al suo equivalente racemico. La sostanza è caratterizzata dalla sua apparenza di polvere cristallina bianca a bianco sporco ed è solubile in acqua e metanolo, rendendola adatta per varie formulazioni farmaceutiche. La sua farmacocinetica prevede un'assorbimento rapido, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione. Gli effetti collaterali comuni possono includere mal di testa, nausea e dolore addominale, mentre l'uso a lungo termine è stato associato a potenziali rischi come carenza di vitamina B12 e maggiore suscettibilità a infezioni gastrointestinali.

Formula: (C₁₇H₁₈N₃O₃S)₂·Mg

InChI: InChI=1/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1

InChI key: InChIKey=KWORUUGOSLYAGD-UHFFFAOYSA-N

SMILES: C(S1=O[Mg+2]2([N]3=C(S(CC4=C(C)C(OC)=C(C)C=N4)=O2)[N-]C=5C3=CC=C(OC)C5)[N]6=C1[N-]C=7C6=CC=C(OC)C7)C8=C(C)C(OC)=C(C)C=N8

Sinonimi:

• (-)-Omeprazole magnesium
• (S)-Omeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]magnesium
• H 199/18
• Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
• Magnesium Bis(5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide)
• Magnesium, bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-, [T-4-(S),(S)]-
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]-, (T-4)-
• Nexium
• Perprazole
• Raciper
• magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide)
• Esomeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]magnesium
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, (T-4)-
• Esomeprazole magnesium Q: What is the CAS Number of
• Esomeprazole Magnesium(Random Configuration)
• Esomeprazole magnesium Esomeprazole magnesium(API)
• 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt
• ESOMEPRAZOLE MAGNESIUM/SODIUM
• Esomeprazole magnesiumQ: What is
• (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1)
• Esomeprazole magnesium Q: What is the storage condition of
• Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide]
• Esomeprazole magnesium Q: What are the applications of
• Esomeprazole magnesium USP/EP/BP
• Chebi:50309
• Esomeprazole magnesium (S-Omeprazole magnesium)
• NEXIUM(esomeprazolemagnesium)
• Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
• Esomeprazole magnesium API
• Esomeprazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt
• ESOMEPRAZOLE MAGNESIUM SAMPLE
• EsMeprazole Magne-siuM Trihydrate
• S-Form magnesium salt

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Formula: C₃₄H₃₆MgN₆O₆S₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 713.1212

Ref: IN-DA001SKP

Esomeprazole Magnesium Salt

CAS: 161973-10-0

Formula: C₁₇H₁₈N₃O₃S·Mg

Colore e forma: White To Off-White Solid

Peso molecolare: 2*344.41 24.30

Ref: 4Z-O-0213

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium

Purezza: ≥98%

Peso molecolare: 713.12g/mol

Ref: 54-BUP13843

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Esomeprazole Magnesium(Random Configuration)

Purezza: 99%

Peso molecolare: 713.12g/mol

Ref: 54-IN11944

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.

Formula: C₃₄H₃₆MgN₆O₆S₂

Purezza: 98.76% - 99.73%

Colore e forma: Solid

Peso molecolare: 713.12

Ref: TM-T2686

Esomeprazole magnesium

CAS: 161973-10-0

Esomeprazole magnesium is a proton-pump inhibitor that is used to treat gastroesophageal reflux disease, Zollinger–Ellison syndrome, and other conditions. Esomeprazole magnesium binds to the H+/K+ ATPase enzyme in the stomach and inhibits acid production. It also decreases the release of histamine from cells in the stomach lining, thereby decreasing gastric acid secretion. This drug has been shown to be effective for treating Helicobacter pylori infections and reducing the risk of ulcers associated with nonsteroidal anti-inflammatory drugs in patients with hepatic impairment or those taking omeprazole. The efficacy of esomeprazole magnesium can be measured by its concentration-time curve, which can be determined through blood sampling.

Formula: (C₁₇H₁₈N₃O₃S)₂•Mg

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 713.12 g/mol

Ref: 3D-FE46488

Esomeprazole Magnesium

CAS: 161973-10-0

Formula: C₃₄H₃₆MgN₆O₆S₂

Peso molecolare: 713.12

Ref: ST-EA-CP-E14022