CAS 162652-95-1

Acido aspidospermidina-3-carbossilico, 4-(acetilossi)-6,7-dideidro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroetil)-1,3,4,5,6,7,8,9-ottaidro-8-(metossicarbonil)-2,6-metano-2H-azecino[4,3-b]indol-8-il]-3-idrossi-16-metossi-1-metil-, estere metilico, (2β,3β,4β,5α,12R,19α)-

Descrizione:

L'acido aspidospermidina-3-carbossilico, 4-(acetyloxy)-6,7-dideidro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroetile)-1,3,4,5,6,7,8,9-octahidro-8-(metossicarbonile)-2,6-metano-2H-azecino[4,3-b]indolo-8-ile]-3-idrossi-16-metossi-1-metile-, estere metilico, con numero CAS 162652-95-1, è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come acidi carbossilici, esteri e gruppi metossilici. Questo composto fa parte di una classe più ampia di alcaloidi, noti per le loro diverse attività biologiche, inclusi potenziali effetti terapeutici. La sua estereochimica è significativa, come indicato dalla configurazione specifica dei suoi centri chirali, che possono influenzare le sue interazioni biologiche e le proprietà farmacologiche. La presenza di gruppi difluoroetile e metossicarbonile suggerisce un potenziale per caratteristiche uniche di reattività e solubilità. In generale, la complessità strutturale e la diversità funzionale di questo composto lo rendono un argomento di interesse nella chimica medicinale e nello sviluppo di farmaci.

Formula: C₄₅H₅₄F₂N₄O₈

InChI: InChI=1S/C45H54F2N4O8/c1-8-42-14-11-16-51-17-15-43(36(42)51)30-19-31(34(56-5)20-33(30)49(4)37(43)45(55,40(54)58-7)38(42)59-25(2)52)44(39(53)57-6)21-26-18-27(41(3,46)47)23-50(22-26)24-29-28-12-9-10-13-32(28)48-35(29)44/h9-14,19-20,26-27,36-38,48,55H,8,15-18,21-24H2,1-7H3/t26-,27+,36-,37+,38+,42+,43+,44-,45-/m0/s1

InChI key: InChIKey=NMDYYWFGPIMTKO-KLCPSUAYSA-N

SMILES: C(C)[C@@]12[C@]3([C@@]4([C@]([C@](C(OC)=O)(O)[C@@H]1OC(C)=O)(N(C)C=5C4=CC(=C(OC)C5)[C@]6(C(OC)=O)C7=C(C=8C(N7)=CC=CC8)C[N@@]9C[C@](C6)(C[C@@H](C(C)(F)F)C9)[H])[H])CCN3CC=C2)[H]

Sinonimi:

• 20',20'-Difluoro-3',4'-dihydrovinorelbine
• 20′,20′-Difluoro-3′,4′-dihydrovinorelbine
• 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine
• 4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine
• 4′-Deoxy-20′,20′-difluoro-5′-norvincaleukoblastine
• 4′-Deoxy-20′,20′-difluoro-8′-norvincaleukoblastine
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-
• C′-Norvincaleukoblastine, 4′-deoxy-20′,20′-difluoro-
• Vinflunine Tartrate
• methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(4S,6S,8S)-4-(1,1-difluoroethyl)-8-(methoxycarbonyl)-1,3,4,5,6,7,8,9-octahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate

Vinflunine

CAS: 162652-95-1

Formula: C₄₅H₅₄F₂N₄O₈

Peso molecolare: 816.9291

Ref: IN-DA001TAT

Vinflunine

CAS: 162652-95-1

Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.

Formula: C₄₅H₅₄F₂N₄O₈

Colore e forma: Solid

Peso molecolare: 816.93

Ref: TM-T7594

Vinflunine

CAS: 162652-95-1

Vinflunine is a synthetic vinca alkaloid, which is derived from the natural alkaloid compounds found in the Madagascar periwinkle plant (Catharanthus roseus). Its mode of action involves inhibiting microtubule assembly, which disrupts cell division and leads to apoptotic cell death. Consequently, vinflunine effectively targets rapidly dividing cancer cells.

Purezza: Min. 95%

Ref: 3D-FV38912