CAS 1629229-37-3

[(8R)-5,6-Diidro-8-metil-3-(3-metil-1,2,4-tiadiazol-5-il)-1,2,4-triazolo[4,3-a]pirazin-7(8H)-il](4-fluorofenil)metanone

Descrizione:

La sostanza chimica con il nome "[(8R)-5,6-Diidro-8-metil-3-(3-metil-1,2,4-tiadiazol-5-il)-1,2,4-triazolo[4,3-a]pirazin-7(8H)-il](4-fluorofenil)metanone" e numero CAS "1629229-37-3" è un composto organico complesso caratterizzato dalla sua struttura a più anelli, che include un moiety di triazolo e pirazina. Questo composto presenta un sostituente di tiadiazolo, contribuendo alla sua potenziale attività biologica. La presenza di un gruppo fluorofenile suggerisce che potrebbe esibire proprietà elettroniche uniche, influenzando potenzialmente la sua reattività e interazione con obiettivi biologici. La stereochimica indicata dalla configurazione (8R) implica disposizioni spaziali specifiche che possono influenzare il profilo farmacologico del composto. Composti di questo tipo sono spesso studiati per le loro potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci mirati a varie malattie. La struttura intricata e i gruppi funzionali suggeriscono che potrebbe possedere proprietà interessanti, comprese possibili attività antimicrobiche o antitumorali, sebbene siano necessari dati biologici specifici per confermare questi effetti.

Formula: C₁₆H₁₅FN₆OS

InChI: InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1

InChI key: InChIKey=PPSNFPASKFYPMN-SECBINFHSA-N

SMILES: C[C@@H]1C=2N(C(=NN2)C=3SN=C(C)N3)CCN1C(=O)C4=CC=C(F)C=C4

Sinonimi:

• (R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
• [(8R)-5,6-Dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)methanone
• (4-Fluorophenyl)[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methanone
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• Fezolinetant
• ESN 364
• Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
• FEZOLINETANT; ESN-364; ESN 364; ESN364

Fezolinetant

CAS: 1629229-37-3

Fezolinetant (ESN-364) is a neurokinin-3 receptor antagonist that is being investigated for menopausal hot flashes.Cost-effective and quality-assured.

Formula: C₁₆H₁₅FN₆OS

Purezza: 98.62% - 99.7%

Colore e forma: Solid

Peso molecolare: 358.39

Ref: TM-T15278

Fezolinetant

CAS: 1629229-37-3

Formula: C₁₆H₁₅FN₆OS

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 358.3933

Ref: IN-DA01EOC7

Fezolinetant

CAS: 1629229-37-3

Fezolinetant

Purezza: ≥98%

Peso molecolare: 358.39g/mol

Ref: 54-BUP04385

Fezolinetant

CAS: 1629229-37-3

Formula: C₁₆H₁₅FN₆OS

Peso molecolare: 358.40

Ref: 4Z-F-240001

Fezolinetant-d4

CAS: 1629229-37-3

Formula: C₁₆H₁₁D₄FN₆OS

Peso molecolare: 362.42

Ref: 4Z-F-240002

Fezolinetant

CAS: 1629229-37-3

Fezolinetant is a drug for the treatment of menopausal symptoms. It is designed to be administered as a single dose, with the primary analysis being a questionnaire on the frequency and severity of symptoms. Fezolinetant has been shown to be efficacious in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Fezolinetant also prevents cancer in mice by inhibiting the invasion and migration of tumor cells. The drug binds to receptors in cells that are involved in cancer cell growth and proliferation, which blocks the production of proteins that are essential for tumor cell division. This drug also has an efficient method of delivery, which may reduce side effects.

Formula: C₁₆H₁₅FN₆OS

Purezza: Min. 95%

Peso molecolare: 358.39 g/mol

Ref: 3D-EQC22937