CAS 163130-29-8

Toremifene N-Oxide Fumarate

CAS: 163130-29-8

Formula: C₂₆H₂₈ClNO₂·C₄H₄O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 421.97 116.07

Ref: 4Z-T-418

Toremifene N-Oxide-d6

Prodotto controllato

CAS: 163130-29-8

Formula: C₂₆D₆H₂₂ClNO₂

Colore e forma: Neat

Peso molecolare: 427.996

Ref: TR-T547512

Toremifene-N-oxide

CAS: 163130-29-8

Toremifene-N-oxide is a drug that has been shown to have genotoxic effects in human liver cells in an incubated system. Toremifene-N-oxide is the active form of toremifene, which is a selective estrogen receptor modulator (SERM). Toremifene-N-oxide is metabolized by peroxidases and can react with reactive oxygen species (ROS) to produce DNA damage. It also binds to DNA at the site of supercoiled DNA, leading to changes in the molecule's structure. Toremifene-N-oxide has been shown to have an optimum pH of 7.4 and ionization mass of 367. This drug binds to lactoperoxidase found in human liver cells and produces reactive molecules that cause oxidative DNA damage.

Formula: C₂₆H₂₈ClNO₂

Purezza: Min. 95%

Peso molecolare: 421.96 g/mol

Ref: 3D-IT158042