CAS 163163-23-3

rel-N-[(3R,4S)-6-Ciano-3,4-diidro-3-idrossi-2,2-dimetil-2H-1-benzopirano-4-il]-N-metiletenosulfonamide

Descrizione:

La sostanza chimica nota come rel-N-[(3R,4S)-6-Ciano-3,4-diidro-3-idrossi-2,2-dimetil-2H-1-benzopirano-4-il]-N-metiletenosulfonamide, con il numero CAS 163163-23-3, è caratterizzata dalla sua complessa struttura molecolare, che include un nucleo di benzopirano, un gruppo ciano e un moiety di sulfonamide. Questo composto presenta proprietà tipiche delle sulfonamidi, come la potenziale attività antibatterica, sebbene la sua specifica attività biologica possa variare. La presenza dei gruppi ciano e idrossile suggerisce che possa partecipare a varie reazioni chimiche, comprese sostituzioni nucleofile o interazioni di legame idrogeno. La stereochimica indicata dalla configurazione (3R,4S) suggerisce che il composto possa esibire chiralità, il che può influenzare le sue proprietà farmacologiche e interazioni con bersagli biologici. Inoltre, la presenza del gruppo dimetile contribuisce alla sua lipofilia, potenzialmente influenzando la sua solubilità e permeabilità nei sistemi biologici. In generale, le caratteristiche strutturali uniche di questo composto possono conferire applicazioni terapeutiche specifiche, giustificando ulteriori indagini sui suoi effetti biologici e meccanismi d'azione.

Formula: C₁₅H₂₀N₂O₄S

InChI: InChI=1/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14-/m1/s1

InChI key: InChIKey=HVSJHHXUORMCGK-DUXBJXIBNA-N

SMILES: N(S(CC)(=O)=O)(C)[C@H]1C=2C(OC(C)(C)[C@@H]1O)=CC=C(C#N)C2

Sinonimi:

• 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane
• Chromanol 239B
• Ethanesulfonamide, N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-N-methyl-, trans-
• Ethanesulfonamide, N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-, rel-
• N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)-N-methylethanesulfonamide
• N-[(3R,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl]-N-methylethanesulfonamide
• N-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl]-N-methylethanesulfonamide
• Trans-N-[6-Cyano-3,4-Dihydro-3-Hydroxy-2,2-Dimethyl-2H-1-Benzopyran-4-Yl]-N-Methyl-Ethanesulfonamide
• rel-N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide
• 293B
• CHROMANOL 293B
• Chromanol 293B >=98% (HPLC), powder
• N-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-methylethanesulfonamide

Ethanesulfonamide, N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-, rel-

CAS: 163163-23-3

Formula: C₁₅H₂₀N₂O₄S

Peso molecolare: 324.3953

Ref: IN-DA001TT9

Chromanol 293B

CAS: 163163-23-3

Formula: C₁₅H₂₀N₂O₄S

Peso molecolare: 324.40

Ref: 7W-GK2240

Chromagnol

CAS: 163163-23-3

Chromagnol is a drug that inhibits the enzyme protein kinase C (PKC). It has been shown to have inhibitory properties on cardiac muscle cells and whole-cell recordings of heart cells. Chromagnol has also been shown to affect the function of bowel disease, including papillary muscle. Chromagnol has been shown to have effects on cardiac and atrial tissue. This drug may be a potential treatment for autoimmune diseases, such as multiple sclerosis, or other diseases that are caused by PKC overactivity. The mechanisms of action are not fully understood but it is believed that chromanol binds to the cytosolic Ca2+ ion channel, preventing it from opening and releasing Ca2+, which leads to an increase in intracellular Ca2+.

Formula: C₁₅H₂₀N₂O₄S

Purezza: Min. 95%

Peso molecolare: 324.4 g/mol

Ref: 3D-FC166930

Chromanol 293B

CAS: 163163-23-3

slow delayed rectifier K+ current (IKs) blocker

Formula: C₁₅H₂₀N₂O₄S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 324.4

Ref: TM-T22662