CAS 16357-59-8

2-Etossi-1-(etossicarbonil)-1,2-diidrochinolina

Descrizione:

2-Etossi-1-(etossicarbonil)-1,2-diidrochinolina è un composto organico caratterizzato dalla sua struttura unica, che include un nucleo di chinolina modificato con gruppi funzionali etossilici ed etossicarbonilici. Questo composto tipicamente mostra proprietà associate sia a sistemi aromatici che alifatici, contribuendo alla sua potenziale reattività e solubilità in vari solventi organici. La presenza dei gruppi etossilici migliora la sua lipofilia, il che può influenzare la sua attività biologica e interazione con altre molecole. Inoltre, la struttura della diidrochinolina suggerisce che potrebbe partecipare a varie reazioni chimiche, come ossidazione o riduzione, a causa della presenza del doppio legame nel sistema ad anello. Questo composto potrebbe essere di interesse nella chimica medicinale, in particolare per le sue potenziali applicazioni nello sviluppo di farmaci o come intermediario sintetico. Le sue caratteristiche specifiche, come il punto di fusione, il punto di ebollizione e i dati spettrali, sarebbero tipicamente determinate attraverso metodi sperimentali e possono variare in base alla purezza e alle condizioni ambientali.

Formula: C₁₄H₁₇NO₃

InChI: InChI=1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3

InChI key: InChIKey=GKQLYSROISKDLL-UHFFFAOYSA-N

SMILES: C(OCC)(=O)N1C=2C(C=CC1OCC)=CC=CC2

Sinonimi:

• 1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester
• 1,2-Dihydro-2-ethoxy-1-quinolinecarboxylic acid e
• 1-(Ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline
• 2-Ethoxy-1(2H)-quinolinecarboxylic acid ethyl ester
• 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
• 2-Ethoxy-N-(ethoxycarbonyl)-1,2-dihydroquinoline
• EEDQ~N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
• Ethyl 1,2-dihydro-2-ethoxy-1-quinolinecarboxylate
• Ethyl 2-ethoxy-1(2H)-quinolinecarboxylate
• N-Carbethoxy-2-ethoxy-1,2-dihydroquinoline
• N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
• NSC 147831
• ethyl (2R)-2-ethoxyquinoline-1(2H)-carboxylate
• ethyl (2S)-2-ethoxyquinoline-1(2H)-carboxylate
• ethyl 2-ethoxyquinoline-1(2H)-carboxylate
• ethyl N-(2-ethoxy-1,2-dihydroquinoline)carboxylate

1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

CAS: 16357-59-8

Formula: C₁₄H₁₇NO₃

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 247.29

Ref: 3B-E0363

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99%

CAS: 16357-59-8

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is an irreversible membrane-bound receptor antagonist. It is used in synthetic chemistry, discovery, process RD. It also acts as coupling reagents.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. So

Formula: C₁₄H₁₇NO₃

Purezza: 99%

Colore e forma: Crystals or powder or crystalline powder, White to cream

Peso molecolare: 247.29

Ref: 02-A13724

EEDQ

CAS: 16357-59-8

EEDQ permits the coupling of acylamino acids with amino acid esters in high yield without concomitant racemization. In a study aiming at the optimization of the coupling of 3,5-dinitrobenzoyl-Leu to 3-aminopropyl-silica (Yang et al.) significant levels of racemization were observed with all the tested coupling reagents except for EEDQ .

Formula: C₁₄H₁₇NO₃

Purezza: > 99%

Colore e forma: Light Beige Powder

Peso molecolare: 247.29

Ref: 01-4015690

1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester

CAS: 16357-59-8

Formula: C₁₄H₁₇NO₃

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 247.2897

Ref: IN-DA001U8Q

Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate

CAS: 16357-59-8

Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate

Formula: C₁₄H₁₇NO₃

Purezza: 99%

Colore e forma: off white crystalline solid

Peso molecolare: 247.29g/mol

Ref: 54-OR61179

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

CAS: 16357-59-8

Formula: C₁₄H₁₇NO₃

Peso molecolare: 247.29

Ref: 7W-GM0340

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

CAS: 16357-59-8

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinolin, also known as EEDQ, is a peptide coupling reagent used to couple acyl amino acids to amino acid esters. EEDQ can be used in a one-step procedure in solution and solid-phase synthesis, achieving good yields with suppression of racemisation. EEDQ is used in the formation of antibody-drug conjugates and DNA-encoded bioconjugates formed from the reaction of an amine, a carboxylic acid and a DNA fragment. EEDQ is also an irreversible dopamine-receptor antagonist (see N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline for Pharmaceutical and Diagnostic Industries).

Formula: C₁₄H₁₇NO₃

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 247.29 g/mol

Ref: 3D-FE40640

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

CAS: 16357-59-8

Formula: C₁₄H₁₇NO₃

Purezza: 95%

Colore e forma: Solid, Powder or Crystalline Powder or Granules or Chunks

Peso molecolare: 247.294

Ref: 10-F003625

EEDQ extrapure, 99%

CAS: 16357-59-8

Formula: C₁₄H₁₇NO₃

Purezza: min. 99%

Colore e forma: White to off-white, Crystalline powder

Peso molecolare: 247.30

Ref: SR-62813

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

Prodotto controllato

CAS: 16357-59-8

Applications 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is used in the synthesis of Glycochenodeoxycholic Acid 3-Sulfate Disodium Salt which is a bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Parmentier, G. , et al.: Steroids, 30, 583 (1977), Tserng, K.Y., et al.: Lipids, 13, 479 (1978),

Formula: C₁₄H₁₇NO₃

Colore e forma: Neat

Peso molecolare: 247.29

Ref: TR-E891880

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

CAS: 16357-59-8

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline is a transcriptional regulator that is structurally related to the 2-adrenergic receptor agonist, clonidine. It binds to the 5HT2 receptor and has been shown to have antimicrobial properties. N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline has been shown to inhibit viral resistance in animals infected with influenza A virus. This drug also inhibits prolactin release in rats and humans through its binding to dopamine receptors. NEDQ is an inhibitor of human serum prolactin release.

Formula: C₁₄H₁₇NO₃

Purezza: Min. 99.0 Area-%

Peso molecolare: 247.30 g/mol

Ref: 3D-E-5001

EEDQ

CAS: 16357-59-8

EEDQ: irreversible dopamine antagonist; specifically reacts with carboxyl groups, couples acylamino acids without racemization.

Formula: C₁₄H₁₇NO₃

Colore e forma: Solid

Peso molecolare: 247.29

Ref: TM-T71923