CAS 16391-75-6

29-Nordammara-17(20),24-dieno-21-acido oico, 16-(acetilossi)-3,11-diidrossi-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, comp. con 2,2′-iminobis[etanolo] (1:1)

Descrizione:

29-Nordammara-17(20),24-dien-21-acido oico, 16-(acetyloxy)-3,11-diidrossi-, è un composto organico complesso caratterizzato dalla sua unica struttura steroidea, che include più gruppi idrossilici e un gruppo funzionale acetyloxy. Questo composto presenta una stereochimica specifica, denotata dalla sua configurazione dettagliata, che influenza la sua attività biologica e le interazioni. La presenza di 2,2′-iminobis[etanolo] indica che forma un complesso 1:1 con questa ammina, potenzialmente influenzando la sua solubilità e reattività. Il composto è probabile che mostri varie proprietà farmacologiche, date le sue caratteristiche strutturali, che possono includere effetti anti-infiammatori o altri effetti terapeutici. Il suo numero CAS, 16391-75-6, consente un'identificazione precisa nei database chimici. In generale, le caratteristiche di questa sostanza suggeriscono che potrebbe avere applicazioni in chimica medicinale o farmacologia, sebbene specifiche attività biologiche richiederebbero ulteriori indagini attraverso studi empirici.

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

InChI: InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

InChI key: InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H].N(CCO)CCO

Sinonimi:

• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid - 2,2'-iminodiethanol (1:1)
• (3alpha,8alpha,9beta,13alpha,14beta,16beta,17(Z))-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1)
• (4alpha,8alpha,9beta,13alpha,14beta,17Z)-16beta-Acetoxy-3alpha,11alpha-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compound with 2,2'-iminodiethanol (1:1)
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, compd. with 2,2′-iminodiethanol (1:1), (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)
• Diethanolamine fusidate
• Ethanol, 2,2′-iminobis-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oate (salt)

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate

Formula: C₃₁H₄₇NaO₆ / C₃₁H₄₈O₆

Purezza: 81.2% / 77.8%

Colore e forma: White

Peso molecolare: 538.32703 / 516.34509

Ref: 47-118

Diethanolamine Fusidate

CAS: 16391-75-6

Formula: C₃₅H₅₉NO₈

Colore e forma: Solid

Peso molecolare: 621.8449

Ref: IN-DA001UJN

Diethanolamine Fusidate

CAS: 16391-75-6

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Colore e forma: White To Off-White Solid

Peso molecolare: 516.72 105.14

Ref: 4Z-F-5418

Diethanolamine Fusidate

CAS: 16391-75-6

Colore e forma: Neat

Ref: 86-MM3832.00

Diethanolamine Fusidate

CAS: 16391-75-6

Stability Hygroscopic
Applications A bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid (F865500). Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Findon, G. et al.: Lab. Anim. Sci., 41, 462 (1991); Parsons, R.L. et al.: Curr. Chemother. Proc. Int. Cong. Chemother., 10, 384 (1978);

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Colore e forma: Neat

Peso molecolare: 621.84

Ref: TR-D441880

Diethanolamine Fusidate

CAS: 16391-75-6

Diethanolamine Fusidate: orally better-absorbed bacteriostatic antibiotic; inhibits protein synthesis in prokaryotes.

Formula: C₃₅H₅₉NO₈

Colore e forma: Solid

Peso molecolare: 621.86

Ref: TM-T70323

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate is an aminoglycoside antibiotic that inhibits protein synthesis in bacteria by binding to the ribosomes. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Diethanolamine fusidate has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₃₅H₅₉NO₈

Purezza: 95%Min

Peso molecolare: 621.84 g/mol

Ref: 3D-FD173301