CAS 166108-71-0

Acido 8-(9-fluorenilmetossicarbonilamino)-3,6-diossoottanoico

Descrizione:

Acido 8-(9-fluorenilmetossicarbonilamino)-3,6-diossoottanoico, comunemente noto come Fmoc-D-OAA, è un composto sintetico utilizzato principalmente nella sintesi di peptidi e come gruppo protettivo per amminoacidi. Questa sostanza presenta uno scheletro di acido dioxaoctanoico, che contribuisce alla sua solubilità e stabilità in vari solventi. La presenza del gruppo fluorenilmetossicarbonile (Fmoc) consente la protezione selettiva del gruppo amminico, facilitando l'assemblaggio passo dopo passo dei peptidi. Fmoc-D-OAA è caratterizzato dalla sua capacità di subire deprotezione in condizioni basiche leggere, rendendolo vantaggioso nella sintesi di peptidi in fase solida. Inoltre, il composto mostra una buona compatibilità con vari reagenti di accoppiamento e può essere utilizzato nella sintesi di peptidi bioattivi. La sua struttura include regioni idrofili e idrofobiche, che possono influenzare la sua interazione con i sistemi biologici. In generale, Fmoc-D-OAA è uno strumento prezioso nel campo della chimica organica e della biochimica, in particolare nello sviluppo di terapie basate su peptidi.

Formula: C₂₁H₂₃NO₆

InChI: InChI=1/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)

InChI key: InChIKey=XQPYRJIMPDBGRW-UHFFFAOYSA-N

SMILES: C(OC(NCCOCCOCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2-[2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Ethoxy]-Ethoxy)-Acetic Acid
• 1-(9H-Fluoren-9-Yl)-3-Oxo-2,7,10-Trioxa-4-Azadodecan-12-Oic Acid
• 1-(9H-Fuoren-9-Yl)-3-Oxo-2,7,10-Trioxa-4-Azadodecan-12-Oic Acid
• 12-(9H-Fluoren-9-yl)-10-oxo-3,6,11-trioxa-9-azadodecanoic acid
• 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
• 2-[2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
• 2-[2-[2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)ethoxy]ethoxy]acetic acid
• 3,6,11-Trioxa-9-azadodecanoic acid, 12-(9H-fluoren-9-yl)-10-oxo-
• 8-(9-Fluorenylmethoxycarbonyl-Amino)-3,6-Dioxa-Octanoic Acid
• 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic acid
• 8-(Fmoc-Amino)-3,6-Dioxa-Octanoic Acid
• 8-(Fmoc-amino)-3,6-dioxaoctanoic acid
• 8-Fluorenylmethoxycarbonylamino-3,6-Dioxaoctanoic Acid
• 9-Fluorenylmethoxycarbonyl-8-Amino-3,6-Dioxaoctanoic Acid
• Fmoc-Aeea-Oh
• Fmoc-Aeeac-Oh
• Fmoc-NH-PEG₂-CH₂COOH
• Fmoc-aeea
• Rarechem Em Wb 0032
• (2-[2-(Fmoc-Amino)-Ethoxy]-Ethoxy)-Acetic Acid
• FMOC-[2-(2-AMINO-ETHOXY)-ETHOXY]-ACETIC ACID
• FMOC-8-AMINO-3,6-DIOXAOCTANOIC ACID
• FMOC-O2OC-OH
• 8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoicacid,{2-[2-(Fmoc-amino)ethoxy]ethoxy}aceticacid,1-(9H-Fuoren
• FMOC-MINI-PEG(TM)
• 8-(9-FLUOROENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID
• 8-(9-Fluorenylmethyloxycarbonyl-amino)-3,6-dioxaoctanoic acid, {2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, 1-(9H-Fuoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid, Fmoc-Ado, Fmoc-AEEA
• 8-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3,6-DIOXAOCTANOIC ACID

8-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3,6-dioxa-n-octanoic Acid

CAS: 166108-71-0

Formula: C₂₁H₂₃NO₆

Purezza: >97.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 385.42

Ref: 3B-F0719

(2-[2-(Fmoc-amino)ethoxy]ethoxy)acetic acid, 95%

CAS: 166108-71-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₁H₂₃NO₆

Purezza: 95%

Peso molecolare: 385.42

Ref: 02-H63641

Fmoc-AEEAc-OH

CAS: 166108-71-0

Hydrophilic heterobifunctional spacer useful to attach chromophores. Building block for the synthesis of spacers of defined length.

Formula: C₂₁H₂₃NO₆

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 385.42

Ref: 01-4037914

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS: 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Formula: C₂₁H₂₃NO₆

Purezza: 99.61%

Colore e forma: White Crystal

Peso molecolare: 385.41

Ref: TM-T15304

3,6,11-Trioxa-9-azadodecanoic acid, 12-(9H-fluoren-9-yl)-10-oxo-

CAS: 166108-71-0

Formula: C₂₁H₂₃NO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 385.4104

Ref: IN-DA001WHY

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS: 166108-71-0

Fmoc-8-amino-3,6-dioxaoctanoic acid

Purezza: ≥98%

Peso molecolare: 385.41g/mol

Ref: 54-BUP19698

{2[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid

CAS: 166108-71-0

{2[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid

Formula: C₂₁H₂₃NO₆

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 385.41g/mol

Ref: 54-OR0969

Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid

CAS: 166108-71-0

Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), these types of compounds are more versatile as they have two different anchor points. Fmoc-mini-PEG Fmoc-8-Amino-3,6-Dioxaoctanoic Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules, and nanoparticles. It is enzyme-cleavable via β-glucuronidase, releasing the drug or payload in enzyme-rich environments.

Formula: C₂₁H₂₃NO₆

Purezza: Min. 95%

Peso molecolare: 385.42 g/mol

Ref: 3D-FXX-5521-PI

Fmoc-AEEA

CAS: 166108-71-0

This PEGylated Fmoc linker is used for controlled conjugation of biomolecules. The cleavage occurs under chemical or enzymatic conditions.

Formula: C₂₁H₂₃NO₆

Purezza: Min. 97.5 Area-%

Colore e forma: Powder

Peso molecolare: 385.41 g/mol

Ref: 3D-FF35496

Fmoc-Amino-3,6 dioxaoctanoic acid

CAS: 166108-71-0

Formula: C₂₁H₂₃NO₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 385.416

Ref: 10-F050302

8-(Fmoc-amino)-3,6-dioxaoctanoic Acid

Prodotto controllato

CAS: 166108-71-0

Applications 8-(Fmoc-amino)-3,6-dioxaoctanoic Acid is a hydrophilic, heterobifunctional spacer.
References Koskinen, A., et al.: Bioorg. Med. Chem. Lett., 5, 573 (1995)

Formula: C₂₁H₂₃NO₆

Colore e forma: Neat

Peso molecolare: 385.41

Ref: TR-F603515