CAS 16808-86-9

6,14-Etenomorfinano-7-metanolo, 17-(ciclopropilmetil)-4,5-epossi-18,19-diidro-3-idrossi-6-metossi-α,α-dimetil-, cloridrato (1:1), (5α,7α)-

Descrizione:

6,14-Etenomorfinano-7-metanolo, 17-(ciclopropilmetil)-4,5-epossi-18,19-diidro-3-idrossi-6-metossi-α,α-dimetil-, cloridrato (1:1), (5α,7α)-, identificato dal numero CAS 16808-86-9, è un composto sintetico appartenente alla classe degli alcaloidi morfinani. Questa sostanza presenta una struttura molecolare complessa caratterizzata da più gruppi funzionali, inclusi gruppi metanolo, epossido e idrossile, che contribuiscono alle sue proprietà farmacologiche. Si incontra tipicamente nel contesto di ricerche relative agli analgesici e potenziali agenti terapeutici a causa della sua interazione con i recettori oppioidi. La presenza del gruppo ciclopropilmetile può influenzare la sua affinità di legame e selettività, impattando la sua efficacia e profilo di sicurezza. Come sale cloridrato, è probabile che sia più solubile in acqua, facilitando il suo utilizzo in varie formulazioni. Le precauzioni di sicurezza e gestione sono essenziali, così come per molti composti di questa classe, a causa dei potenziali effetti psicoattivi e delle considerazioni normative.

Formula: C₂₆H₃₅NO₄·ClH

InChI: InChI=1S/C26H35NO4.ClH/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25;/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3;1H/t18-,19-,22-,24-,25+,26-;/m1./s1

InChI key: InChIKey=UNPUINKKJUSSDZ-UVGWPQHUSA-N

SMILES: O(C)[C@@]12[C@]3([C@]45[C@@]([C@](N(CC6CC6)CC4)(CC7=C5C(O3)=C(O)C=C7)[H])(C[C@@H]1[C@@](C)(C)O)CC2)[H].Cl

Sinonimi:

• (5alpha,7alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-6,14-ethenomorphinan-7-methanol hydrochloride
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride (1:1), (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride, (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 18,19-dihydro-17-(cyclopropylmethyl)-alpha,alpha-dimethyl-4,5-epoxy-3-hydroxy-6-methoxy-, hydrochloride, (5-alpha,7-alpha)-
• 6,14-endo-Ethanetetrahydrooripavine, 21-cyclopropyl-7-alpha-(1-hydroxy-1-methylethyl)-, HCl
• 6,14-endo-Ethanotetrahydrooripavine, 21-cyclopropyl-7α-(1-hydroxy-1-methylethyl)-, hydrochloride
• Diprenorphine hydrochloride
• Revivon

Diprenorphine Hydrochloride (1 mg/ml in Methanol)

Prodotto controllato

CAS: 16808-86-9

Formula: C₂₆H₃₅NO₄·ClH

Colore e forma: Single Solution

Peso molecolare: 462.02

Ref: TR-KIT4458

Diprenorphine-d3 Hydrochloride

Prodotto controllato

CAS: 16808-86-9

Applications Labelled Diprenorphine (D492100). Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Formula: C₂₆H₃₃D₃ClNO₄

Colore e forma: Neat

Peso molecolare: 465.04

Ref: TR-D492102

Diprenorphine Hydrochloride

Prodotto controllato

CAS: 16808-86-9

Applications Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Formula: C₂₆H₃₅NO₄·ClH

Colore e forma: Neat

Peso molecolare: 462.02

Ref: TR-D492100

Diprenorphine hydrochloride

Prodotto controllato

CAS: 16808-86-9

Diprenorphine hydrochloride is a drug that belongs to the class of opioids. It is used as an antidote for opioid overdose and has been shown to be effective in reducing the severity of withdrawal symptoms. Diprenorphine hydrochloride has been shown to inhibit P-glycoprotein (P-gp), which is a membrane protein that transports certain substances from the brain back into the blood. This inhibition leads to increased concentrations of dopamine in the brain, which may contribute to its clinical relevance as an anti-psychotic agent. Diprenorphine hydrochloride also has binding affinity for μ-, κ-, δ-, and ν-opioid receptors, which can lead to decreased locomotor activity, antinociceptive effects, and sedation.

Formula: C₂₆H₃₆ClNO₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 462.02 g/mol

Ref: 3D-FD22520